8 research outputs found

    Tek taraflı cerrahi destekli hızlı üst çene genişletmesi

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    İskeletsel tek taraflı posterior çapraz kapanış özellikle yetişkinlerde tedavisi zor bir anomalidir. Genç bireylerde bu problemin çözümünde kolaylıkla uygulanan hızlı maksiler genişletme, yetişkinlerde maksillanın çevre yüz kemikleriyle yaptığı artikülasyonların rijiditesindeki artma nedeniyle maksillada yapılan kortikotomiler yardımıyla uygulanmaktadır. Bu yolla yapılan çift taraflı genişletme darlık olmayan tarafta da genişlemeye sebep olmakta, bu da tedavi süresini uzatmaktadır. Bu olgu sunumunda 16 yaşında, tek taraflı posterior çapraz kapanışı olan bayan hastada, tek taraflı kortikotomi ve hızlı üst çene genişletmesini takiben yapılan ortodontik tedavi sunulmuştur. Ekspansiyon sonrası darlık olmayan tarafta aşırı bir genişlemeye sebep olmadan, iyi bir okluzyon ve estetik bir gülümseme elde edilmiştir

    Does proclination of maxillary incisors really affect the sagittal position of point A?

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    Objective: To examine the effect of maxillary incisor proclination due to orthodontic treatment upon the sagittal position of point A and evaluate the effect of this possible movement of point A on sella-nasion-point A (SNA) angle. Materials and Methods: A study group was formed from 25 subjects (12 male and 13 female) who had Class II division 2 malocclusion with retroclined upper incisors, and a control group was formed from 25 subjects (12 male and 13 female) who had minor crowding in the beginning of the treatment and required no or minimal maxillary anterior tooth movement. Treatment changes in maxillary incisor inclination, sagittal position of point A, SNA angle, and movement of incisor root apex and incisal edge were calculated on pretreatment and posttreatment lateral cephalographs. Results: Maxillary incisors were significantly proclined (17.33 degrees) in the study group and not significantly proclined (1.81 degrees) in the control group. This proclination resulted in 2.12-mm backward movement of the root apex and 5.76-mm forward movempnt of the incisal edge of maxillary incisors. Point A moved 1.04 mm backward (P = .582) and 0.48 mm (P = .811) forward in the study and control groups, respectively. Incisor root apex and incisal edge almost remained stable in the control group. No significant change was observed in the value of the SNA angle in both the study and control groups. Conclusions: Proclination of maxillary incisors accompanied by backward movement of incisor root apex caused posterior movement of point A. However, this posterior movement does not significantly affect the SNA angle

    Kilroy spring kullanılarak gömülü üst kanin sürdürülmesi

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    Gömülü üst kanin dişlerin ortodontik olarak sürdürülmesi, birçok ortodontist tarafından zor bir tedavi olarak değerlendirilmektedir. Gömülü dişlerin sürdürülmesi sırasında komşu dişlerde meydana gelebilecek kök rezorbsiyonları, rutin tedavi teknikleri dışında farklı mekaniklere ihtiyaç duyulması, ankraj gereksinimlerinin fazla ve farklı olması gibi nedenler tedavinin güçlüğüne sebep olarak sayılabilir. Bu çalışmada, Kilroy spring isimli gömülü kaninlerin sürdürülmesi amacıyla dizayn edilmiş, devamlı kuvvet uygulayan ve tüm üst dişlerden ankraj alan bir aparey kullanılarak tedavi edilen 2 vaka sunulmaktadır

    Comparative analysis of pomological and phytochemical characteristics in white- and red-fleshed pitaya (Hylocereus spp.), with molecular docking insights into key bioactive compounds

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    BACKGROUND Cacti, including pitaya (Hylocereus spp.), are rich in antioxidants that will undoubtedly gain importance under ongoing climate change as water resources decline. Yet the molecular basis linking composition to antioxidant function remains incompletely defined. We compared white-fleshed H. undatus and red-fleshed H. polyrhizus across physicochemical traits, integrating correlation, principal component analysis, and molecular docking to a human iron-regulatory protein (IRP1).RESULTS White-fleshed fruits were larger and heavier (length 103.4 mm; width 60.2 mm; weight 204.7 g) than red-fleshed (71.9 mm; 54.5 mm; 126.3 g). Conversely, red-fleshed fruits showed higher total soluble solids (13.47 vs. 9.60 degrees Brix), total phenolics (379.7 vs. 183.0 mg L-1), total flavonoids (303.7 vs. 147.3 mg L-1), and antioxidant activity (52.3% vs. 30.0%). Organic acids and phenolics differed by species (e.g., higher citric acid in red; higher malic acid in white). Correlations indicated that greater soluble sugars were associated with higher phenolic accumulation, consistent with the elevated antioxidant capacity of red-fleshed fruit. The first two principal components explained 83.3% of the total variance (PC1 = 68.8%, PC2 = 14.5%) and separated samples along size/degrees Brix versus phenolic/ antioxidant axes. Docking predicted favorable binding of major acids and phenolics to IRP1, suggesting plausible antioxidant mechanisms.CONCLUSION Findings support species-specific use, with red-fleshed H. polyrhizus serving as a nutrient-dense source of antioxidant compounds, while white-fleshed H. undatus offers advantageous pomological traits. Integrating compositional profiling with multivariate analysis and docking provides mechanistic context and practical implications for breeding, climate-resilient cultivation, and industrial applications. (c) 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.Leibniz Universitat HannoverThe publication of this article was funded by the Open Access Fund of Leibniz Universitat Hannover

    Operational Evaluation of Pilot-Scale Side-Line Treatment Based on Microbial Population and Activity

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    A pilot-scale study conducted in a municipal wastewater treatment plant (WWTP) for short-cut biological nitrogen removal (SBNR) from anaerobic reject water (ARW) was evaluated based on the microbial population and activity to assess optimum operational modes and effective parameters. Two main periods, one- and two-stage sequential batch reactor (SBR) systems, were operated at multiple-feeding mode + high sludge age + ambient temperature (during hot and cold seasons) and two separate process/reactor configurations with back feeding + controlled temperature (20 degrees C, 25 degrees C, 30 degrees C, and 35 degrees C) conditions, respectively. One-stage SBR operation at high temperature, moderate hydraulic retention time (HRT), and multiple-feeding mode promoted high sludge age and bacterial count and activity at the highest level for ammonium-oxidizing bacteria (AOB) and denitrifying bacteria (DB) where other species common in municipal WWTPs, Actinobacteria (filamentous bacteria) and Accumulibacter (phosphate-removing bacteria), dropped substantially in population number. Nitrospira was the only nitrite-oxidizing bacteria (NOB) species detected, ranging at the lowest level during the one-stage SBR operation period, showed a tendency to wash out, and rose in population in the full aerobic SBR of the two-stage operation. An overall bacterial activity and viability loss obtained in the two-stage SBR operation resulted in reduced sludge age values with a severe deterioration in the denitrifying anoxic SBR (AnSBR), which was correlated with the limited level of suitable substrate, thus, starving condition. The contribution of the anaerobic bacteria activity and slowly degrading organic matter oxidation in the one-stage SBR operation was pronounced in the study where the sludge age obtained was found as the most significant parameter in comparison with temperature and HRT.Turkish Scientific and Technological Research Council (TUBITAK, TR) [113Y180]; Konya Administration of Water and Sewerage (TR) [113Y180]This study was conducted within the Research Project (113Y180) supported by the Turkish Scientific and Technological Research Council (TUBITAK, TR) and the Konya Administration of Water and Sewerage (TR). The author thanks Bulent Mertoglu, Bioengineering Department of Marmara University (TR), for carrying out the real-time PCR analyses

    Enhanced solid waste stabilization in aerobic landfills using low aeration rates and high density compaction

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    Historically, municipal solid waste landfills have been designed and operated as storage facilities with suboptimal degradation under anaerobic conditions resulting in slow waste stabilization, gaseous emissions and leachate formation. This article examines the aerobic bioreactor alternative combining the recirculation of high strength leachate [chemical oxygen demand (COD): 89,000-95,600 mg-l; biological oxygen demand (BOD): 75,700-80,000 mg-l)] with low aeration rates (0.0125-0.05 l-min.kg) at high initial waste compaction (657-875 kg-m3) to promote and control biodegradation of solid waste in laboratory-scale columns (diameter = 60 cm, height = 1 m). Low aeration rates coupled with high initial density demonstrated improved performance with increased levels of stabilization with COD and BOD attenuation reaching up to 96percent, final C:N ratio of 25 and waste settlement up to 55percent. © The Author(s) 2013.Abichou T, 2006, WASTE MANAGE, V26, P1305, DOI 10.1016-j.wasman.2005.11.016; APHA, 1998, STANDARD METHODS EXA; Ballik I., 2009, CDM INVESTMENT NEWSL; Berge ND, 2005, CRIT REV ENV SCI TEC, V35, P365, DOI 10.1080-10643380590945003; Bilgili MS, 2007, J HAZARD MATER, V143, P177, DOI 10.1016-j.jhazmat.2006.09.012; Bilgili MS, 2007, J HAZARD MATER, V145, P186, DOI 10.1016-j.jhazmat.2006.11.014; Bilgili MS, 2006, ENVIRON MANAGE, V38, P189, DOI 10.1007-s00267-005-0179-1; Borglin SE, 2004, J AIR WASTE MANAGE, V54, P815; Borjesson G, 2000, ENVIRON SCI TECHNOL, V34, P4044, DOI 10.1021-es991350s; Donovan SM, 2010, SCI TOTAL ENVIRON, V408, P1979, DOI 10.1016-j.scitotenv.2009.12.011; Edgers L., 1992, P MED C ENV GEOT CES, P177; ElFadel M, 1997, J ENVIRON MANAGE, V50, P1, DOI 10.1006-jema.1995.0131; El-Fadel M, 2002, WASTE MANAGE, V22, P269, DOI 10.1016-S0956-053X(01)00040-X; El-Fadel M., 2001, MUNICIPAL SOLI UNPUB; El-Fadel M, 2000, CRIT REV ENV SCI TEC, V30, P327, DOI 10.1080-10643380091184200; Erses AS, 2008, BIORESOURCE TECHNOL, V99, P5418, DOI 10.1016-j.biortech.2007.11.008; Fricke K, 2005, WASTE MANAGE, V25, P799, DOI 10.1016-j.wasman.2004.12.018; Giannis A, 2008, WASTE MANAGE, V28, P1346, DOI 10.1016-j.wasman.2007.06.024; Hanashima M., 1999, P SARD 99 7 INT WAST, P313; He PJ, 2011, J ENVIRON SCI-CHINA, V23, P1011, DOI 10.1016-S1001-0742(10)60574-8; Hossain M. S., 2010, Geotechnical and Geological Engineering, V28, DOI 10.1007-s10706-009-9299-3; Hossain MS, 2003, J GEOTECH GEOENVIRON, V129, P1151, DOI 10.1061-(ASCE)1090-0241(2003)129:12(1151); IPCC, 2007, CLIM CHANG 2007 PHYS; Ishigaki T, 2005, ENVIRON GEOL, V48, P845, DOI 10.1007-s00254-005-0008-0; Jun D, 2007, J HAZARD MATER, V147, P240, DOI 10.1016-j.jhazmat.2007.01.001; Kim H., 2005, THESIS U FLORIDA US; Kossoy A., 2010, STATE TRENDS CARBON; Kumar S, 2011, CRIT REV BIOTECHNOL, V31, P77, DOI 10.3109-07388551.2010.492206; Larson D. F., 2008, 4761 WORLD BANK DEV; Li XJ, 2008, BIORESOURCE TECHNOL, V99, P359, DOI 10.1016-j.biortech.2006.12.009; Liu CF, 2008, BIORESOURCE TECHNOL, V99, P882, DOI 10.1016-j.biortech.2007.01.013; Mackie KR, 2009, ENVIRON MODELL SOFTW, V24, P1223, DOI 10.1016-j.envsoft.2009.04.003; Mehta R, 2002, J ENVIRON ENG-ASCE, V128, P228, DOI 10.1061-(ASCE)0733-9372(2002)128:3(228); Mertoglu B, 2006, PROCESS BIOCHEM, V41, P2359, DOI 10.1016-j.procbio.2006.06.014; Nikolaou A, 2010, ENVIRON TECHNOL, V31, P1381, DOI 10.1080-09593331003743104; Peterson C, 2009, CDM INVESTMENT NEWSL; Price GA, 2003, WASTE MANAGE, V23, P675, DOI 10.1016-S0956-053X(03)00104-1; Rendra S, 2007, ENVIRON TECHNOL, V28, P609, DOI 10.1080-09593332808618822; Rich C, 2008, WASTE MANAGE, V28, P1039, DOI 10.1016-j.wasman.2007.03.022; Spokas K, 2003, WASTE MANAGE, V23, P599, DOI 10.1016-S0956-053X(03)00102-8; Tchobanoglous G., 1993, INTEGRATED SOLID WAS; Thompson S, 2009, WASTE MANAGE, V29, P2085, DOI 10.1016-j.wasman.2009.02.004; Unnikrishnan, 2010, RESOURCES CONSERVATI, V54, P630; Vigneron V, 2005, WATER SCI TECHNOL, V52, P289; Warith M, 2002, WASTE MANAGE, V22, P7, DOI 10.1016-S0956-053X(01)00014-9; Warith M., 2003, EMIRATES J ENG RES, V8, P61; Yang YF, 2012, WASTE MANAGE RES, V30, P255, DOI 10.1177-0734242X11413328; Zhang HH, 2008, ATMOS ENVIRON, V42, P5579, DOI 10.1016-j.atmosenv.2008.03.01011

    Determinants of optimal aerobic bioreactor landfilling for the treatment of the organic fraction of municipal waste

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    Historically, municipal solid waste landfills have been designed and operated as disposal facilities with suboptimal degradation under anaerobic conditions, resulting in slow waste stabilization and generation of landfill gas rich in methane and high strength leachate. Recently, aerobic bioreactor landfilling is being promoted as a promising method that enhances waste stabilization while producing a relatively weaker leachate and no methane generation. The authors review transformation processes and benefits associated with aerobic bioreactor landfilling. Factors affecting the operation of aerobic bioreactor landfills were detailed and performance indicators were defined with technical and operational considerations. The article emphasizes conditions for economic viability of the technology and concludes with outlining existing gaps and future research needs to improve the understanding and performance of aerobic bioreactor landfilling. © 2014 Copyright © Taylor and Francis Group, LLC.Abichou T, 2006, WASTE MANAGE, V26, P1305, DOI 10.1016-j.wasman.2005.11.016; Agadag O. N., 2005, CHEMOSPHERE, V59, P871; Agadag O. 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    Readmission Rates Within the First 30 and 90 Days After Severe Copd Exacerbations (race Study)

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    Chronic obstructive pulmonary disease (COPD) frequently results in hospital readmission and contributes to increased morbidity and mortality. This multicenter prospective study aimed to identify factors that increase the risk of readmission within 30 to 90 days of severe COPD exacerbation. A total of 415 patients admitted to the emergency department (ED) or general pulmonology ward after discharge due to severe exacerbations from 13 tertiary centers in Turkey were included. Of the participants, 346 (83.4%) were male and 69 (16.6%) were female, with an average age of 69.0 ± 9.1 years. Readmissions within 30 and 90 days after the initial hospitalization occurred in 176 (42.4%) and 191 (46%) patients, respectively. Prospective data collection focused on exacerbation severity, disease severity, and the utility of initial admissions. Factors for 30 to 90 day readmission were analyzed using univariate and multivariate regression models. A 30-day readmission correlated significantly with Hospital Anxiety Depression Scale scores above 16 [odds ratio [OR] 95% confidence intervals [CI]: 1.9 (1.1-3.6); P = .042], severe exacerbation history in the previous year [OR 95% CI: 1.7 (1.1-2.9); P = .038], hospital-acquired pneumonia [OR 95% CI: 1.9 (1-4.1); P = .049)], and frequent antibiotic use in the previous year [OR 95% CI: 1.8 (1.2-2.7); P = .007]. Risk factors for 90-day readmissions included: Grades 3 to 4 tricuspid regurgitation [OR 95% CI: 2.2 (1.1-4.4); P = .024], 2 or more moderate COPD exacerbations [OR 95% CI: 1.9 (1.2-3.1); P = .010], severe exacerbation history in the previous year [OR 95% CI: 2.5 (1.5-4.2); P = .001], immunosuppression [OR 95% CI: 2.7 (1.2-5.7); P = .013], frequent antibiotic use the previous year [OR 95% CI: 1.5 (1-2.4); P = .048], hospitalization via the ED [OR 95% CI: 1.6 (1.1-2.6); P = .028]. To mitigate complications and readmissions, patients with a history of frequent severe COPD exacerbations, high anxiety and depression scores, frequent antibiotic requirements, immunosuppression, tricuspid regurgitation, hospital-acquired pneumonia, and those admitted to the ED should be prioritized for remote monitoring after initial discharge. © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.Turkish Thoracic Societ
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