51 research outputs found
Post traumatic epilepsy : An analysis of interesting spectrum of cases at a tertiary care neurosurgical centre
No full textObjective: We present some unusual cases of post traumatic epilepsy managed in the high care unit of a tertiary care neurosurgical centre. They were thouroughly evaluated to determine the cause of post traumatic epilepsy. The pathogenesis of Post Traumatic Epilepsy which provides insights into neural injury, rewiring and regeneration paradigms is discussed.
Materials and methods: Six male patients aged 19-35 years who suffered head injury and suffered post traumatic epilepsy were enrolled & observed during their hospital stay. They underwent neuroimaging and EEG monitoring to rule out other causes of epilepsy. Two patients were lost due to death.
Results: All patients suffered Parenchymal injury. Seizure spectrum included not only motor but also autonomic manifestations. The Autonomic manifestations were more resistant to antiseizure medication but responded to SOS treatment Seizure threshold is probably reduced during episodes of wound site infection, URTI or urinary infections
Conclusion: The mechanisms causing seizures in TBI patients are incompletely understood. In our set of patients, the common thread that runs through these cases is that they all had severe brain insults followed by post traumatic epilepsy. Cortical lesions seem important in the genesis of the epileptic activity, and early seizures are likely to have a different pathogenesis than late seizures
Rationalising health care in india : Challenges & strategies
No full textAn overview of health care delivery in India is essential, if we are to plan and to improve health care delivery and the indices of health in the coming decades. The health sector in India is a mix of private and government services. While some health care indices appear dismal, several others, including life expectancy are heartening. A balance between regulation and free enterprise is possibly the best option. In this paper we provide a glimpse of health and health related statistics & a n overview of the public health care delivery systems. In the end, we offer suggestion on rationalisation of health care delivery to provide maximum services for the majority of our population within the budget of an optimal health care system outla
Mathai-Quillen forms and Lefschetz theory
No full textMathai-Quillen forms are used to give an integral formula for the Lefschetz number of a smooth map of a closed manifold. Applied to the identity map, this formula reduces to the Chern-Gauss-Bonnet theorem. The formula is computed explicitly for constant curvature metrics. There is in fact a one-parameter family of integral expressions. As the parameter goes to infinity, a topological version of the heat equation proof of the Lefschetz fixed submanifold formula is obtained. As the parameter goes to zero and under a transversality assumption, a lower bound for the number of points mapped into their cut locus is obtained. For diffeomorphisms with Lefschetz number unequal to the Euler characteristic, this number is infinite for most metrics, in particular for metrics of non-positive curvature.First author draf
On a Generalized Entropy Measure Leading to the Pathway Model with a Preliminary Application to Solar Neutrino Data
No full textAn entropy for the scalar variable case, parallel to Havrda-Charvat entropy, was introduced by the first author, and the properties and its connection to Tsallis non-extensive statistical mechanics and the Mathai pathway model were examined by the authors in previous papers. In the current paper, we extend the entropy to cover the scalar case, multivariable case, and matrix variate case. Then, this measure is optimized under different types of restrictions, and a number of models in the multivariable case and matrix variable case are obtained. Connections of these models to problems in statistical and physical sciences are pointed out. An application of the simplest case of the pathway model to the interpretation of solar neutrino data by applying standard deviation analysis and diffusion entropy analysis is provided
Evolution and future trends in battle injuries to the CNS
No full textDespite advances in personal protection, brain and spinal injuries amongst combatants pose significant management challenges. Battle field medical care has evolved over the year. In this article we discuss evolutions of military medicine, study current protocols and outcomes and discuss future perspectives. Mention is also made of some original work by the author
Dynamics of finite-sized light spheres in turbulence
No full textWe report experimental results on the Lagrangian dynamics of finite-size light particles in turbulence. Using an orthogonal camera setup and 3D particle tracking, we study the velocity and acceleration statistics of rigid light spheres in a water tunnel with nearly homogeneous and isotropic turbulence. The Reynolds number (ReY) is varied from 180 to 300, and the study covers a range of size ratios (4 < D/η < 16) for marginally light spheres. We find that the normalised acceleration PDF decreases in intermittency with increasing size ratio - in qualitative agreement with the predictions of the Faxén corrected model. We also present preliminary results on the rotational dynamics of large light spheres in turbulence
Algebra cochains, the bivariant JLO cocycle and the Mathai-Quillen form
No full textThis is a first investigation by the author of the similarity between
Quillen's superconnection formalism, his constructions of (periodic) cyclic
cocycles via algebra cochains on a bar construction, and Kasparov bimodules for
KK-theory. In this article, we do so by deriving a slight extension of the
Mathai-Quillen Thom form via a bivariant JLO cocycle. The main idea (which is
in fact not really new) is that KK-cycles should be thought of as
superconnection forms; these methods will be applied to other contexts
elsewhere
Non-invasive ventilation in the postoperative period: Is there a role?
No full textNon-invasive positive pressure ventilation or non-invasive ventilation (NIV) has emerged as a simpler and safer alternative to invasive mechanical ventilation in patients developing acute postoperative respiratory failure. The benefits of NIV as compared to intubation and mechanical ventilation include lower complications, shorter duration of hospital stay, reduced morbidity, lesser cost of treatment and even reduced mortality rates. However, its use may not be uniformly applicable in all patient groups. This article reviews the indications, contraindications and evidence supporting the use of NIV in individual patient groups in the postoperative period. The anaesthesiologist needs to recognise the subset of patients most likely to benefit from NIV therapy so as to apply it most effectively. It is equally important to promptly identify signs of failure of NIV therapy and be prepared to initiate alternate ways of respiratory support. The author searched PubMed and Ovid MEDLINE, without date restrictions. Search terms included Non-invasive ventilation, postoperative and respiratory failure. Foreign literature was included, though only articles with English translation were used
T-duality of singular spacetime compactifications in an H-flux
No full textWe begin by presenting a symmetric version of the circle equivariant T-duality result in a joint work of the second author with Siye Wu, thereby generalizing the results there. We then initiate the study of twisted equivariant Courant algebroids and equivariant generalized geometry and apply it to our context. As before, T-duality exchanges type II role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; display: inline-block; line-height: normal; font-size: 16.2px; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; position: relative; \u3eIIA and type II role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; display: inline-block; line-height: normal; font-size: 16.2px; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; position: relative; \u3eIIB string theories. In our theory, both spacetime and the T-dual spacetime can be singular spaces when the fixed point set is non-empty; the singularities correspond to Kaluza–Klein monopoles. We propose that the Ramond–Ramond charges of type II role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; display: inline-block; line-height: normal; font-size: 16.2px; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; position: relative; \u3eII string theories on the singular spaces are classified by twisted equivariant cohomology groups, consistent with the previous work of Mathai and Wu, and prove that they are naturally isomorphic. We also establish the corresponding isomorphism of twisted equivariant Courant algebroids
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