117,954 research outputs found
Data and analyses for the paper "The functional architecture of mother-infant communication in Rhesus Macaques and Humans: same but different", by V. Sclafani, L. De Pascalis, L. Bozicevic, A. Sepe, P. F. Ferrari, and L. Murray
No full textData and analyses for the paper "The functional architecture of mother-infant communication in Rhesus Macaques and Humans: same but different", by V. Sclafani, L. De Pascalis, L. Bozicevic, A. Sepe, P. F. Ferrari, and L. Murra
The Charter of public space
No full textThe idea of a Charter of Public Space was launched by Pietro Garau, international curator of the Biennial of Public Space.
The need for a shared definition of public space was what prompted by he international curator of the Biennial of Public Space to launch in 2013 the idea of a “Charter of Public Space”.
A strong push to help turn this concept into reality was the idea, developed in partnership with Marichela Sepe, to present it at a side event during the 2012 World Urban Forum in Naples. During that event, useful inputs were collected. A public-space partnership was also born between INU and UN-Habitat, the main organizer of the Forum. This led to UN-Habitat’s participation in the second Biennial, the signing of an agreement of cooperation with INU, the joint organization of an international Expert Group Meeting on Public Space and Sustainable Urban Development (Rome, January 2014), and INU’s selection as partner in the preparation of a “Global Public Space Toolkit”. The Toolkit, a tool based on the Charter’s three main themes (design, development and management of public spaces) was presented at the 2014 World Urban Forum in Medellin, Colombia.
Immediately after the 2012 WUF in Naples, Lucia Lancerin joined the drafting group and provided a fundamental contribution by inserting the Charter’s project in the nation-wide “Journey to Good Practice Municipalities” conceived to involve local governments in the Biennial’s preparatory process
The effect of protein supplement on the quantity, quality and moult of cashmere fibre in Cashmere goats kept at pasture in Southern Italy.
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Fleece and somatic traits in F1 kids produced by cross-breeding Scottish cashmere male with Mediterranean genetic types of goats
No full textNonlinear Computer Model for the Simulation of Lock-in Vibration on Long-Span Bridges
No full textThe susceptibility of modern bridges to vortex-shedding-induced vibration is a major concern for researchers and designers. The relevance of this phenomenon is associated with the onset of large-amplitude aeroelastic vibration at moderate wind-velocity regimes due to synchronization, that is, lock-in, of the vortex shedding frequencies with those corresponding to the natural modes of the structure. Recent observations, either recorded during the monitoring of full-scale bridges or during experimental tests of deck models in wind tunnels, confirm the importance of these aspects during the operational life of the structure. In this article, a computer model for the simulation of the aeroelastic loading associated with vortex shedding in lock-in regime is presented, for a direct application to dynamic analysis of long-span bridges. This approach is based on earlier work focused on the response of slender vertical cylindrical chimneys to vortex-shedding excitation, which is here extended to noncircular cross sections. The numerical model was employed in conjunction with a finite-element code for time-domain nonlinear simulation of the structural dynamic response. The validation of the procedure is performed through numerical simulation, conducted on two specific bridge examples
MARICHELA SEPE - Planning and Place in the City. Mapping Place Identity (2013)
No full textMARICHELA SEPE
Planning and Place in the City. Mapping Place Identity
Routledge, New York, 2013, 352 p. Englis
HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma.
No full textPiscuoglio S, Zlobec I, Pallante P, Sepe R, Esposito F, Zimmermann A, Diamantis I, Terracciano L, Fusco A & Karamitopoulou E (2012) Histopathology 60, 397-404 HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma Aims: Pancreatic ductal adenocarcinoma follows a multistep model of progression through precursor lesions called pancreatic intraepithelial neoplasia (PanIN). The high mobility group A1 (HMGA1) and high mobility group A2 (HMGA2) proteins are architectural transcription factors that have been implicated in the pathogenesis and progression of malignant tumours, including pancreatic cancer. The aim of this study was to explore the role of HMGA1 and HMGA2 in pancreatic carcinogenesis. Methods and results: HMGA1 and HMGA2 expression was examined in 210 ductal pancreatic adenocarcinomas from resection specimens, combined on a tissue microarray also including 40 examples of PanIN and 40 normal controls. The results were correlated with the clinicopathological parameters of the tumours and the outcome of the patients. The percentage of tumour cells showing HMGA1 and HMGA2 nuclear immunoreactivity correlated positively with increasing malignancy grade and lymph node metastasis. Moreover, HMGA1 and HMGA2 expression was significantly higher in invasive carcinomas than in PanINs. No, or very low, expression was found in normal pancreatic tissue. Conclusions: Our results suggest that HMGA1 and HMGA2 are implicated in pancreatic carcinogenesis and may play a role in tumour progression towards a more malignant phenotype
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