1,720,975 research outputs found
UJI EFEKTIVITAS ANTIDIARE EKSTRAK ETANOL DAUN GELUGUR (Garcinia atroviridis Griff ex. T Anderson)TERHADAP TIKUS JANTAN PUTIH (Rattus norvegicus) DENGAN LOPERAMIDE SEBAGAI PEMBANDING
Full text linkGelugur leaf (Garcinia atroviridis Griff ex T. Anderson) is a kind of nadir is believed to origanate from the wild forest of Peninsular Malaysia. Gelugur leaves have antidiarrheal compounds in the shapes of tannins and flavonoids to reduce diarrhea. The purpose of this study was to find out the antidiarrheal activity of the ethanolic extract of gelugur leaf in white male rats. The antidiarrheal effect was tested on 15 white male rats with 5 treatment groups, namely, a negative control group of 1% CMC Na, a positive control group of loperamidee hcl, and a treatment group of ethanol extract of gelugur leaves at a dose of 150 miligrams/kgBW, a dose of 300 miligrams/kgBW, and 600 miligrams/kg body weight. Each group was given oral treatment and observations were made on the onset of diarrhea, frequency of diarrhea, and stool consistency. Tests were carried out using an experimental method. The ethanol extract of gelugur leaves was made by maceration method using 96% ethanol. The results of the study on the onset of diarrhea were EEDG 600 miligrams/kgBB (60 minutes), a good decrease in diarrhea frequency was indicated by EEDG 600 miligrams/kgBB (4 times), a good decrease in stool weight was shown by EEDG 600 miligrams/ kgBB (0,7757 grams), good consistency was also shown in the EEDG 600 miligrams/kgBB (soft stools. The data were statistically analyzed using One Way Anova. The results of data analysis from the three EEDG groups affected the decrease in diarrhea because the sig value <0.05 Based on One Way Anova analysis, the five most effective treatments were loperamidee, 600 miligrams/kgBB, EEDG at 300 miligrams/kgBB, EEDG at 150 miligrams/kgBB, and CMC Na 1%. The conclusion in this study is that EEDG 600 miligrams/kgBB has antidiarrheal activity induced by oleum recini when compared with EEDG concentrations of 150 miligrams/kgBB and 300 miligrams/kgBB
FORMULASI DAN eval_UASI SEDIAAN SHAMPOO EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum) SEBAGAI PENUMBUH RAMBUT PADA TIKUS PUTIH
Full text linkDaun Cengkeh (Syzygium aromaticum) memiliki khasiat untuk mengatasi permasalahan pertumbuhan rambut. Yang dimana senyawa yang terkandung didalam daun cengkeh adalah eugenol yang berkhasiat sebagai penumbuh rambut. Tujuan dari penelitian iniadalah mengetahui sebuah efektivitas dari suatu sediaan shampoo dengan menggunakan ekstrak etanol daun cengkeh sebagai pembantu dalam mengatasi rambut rontok, dengan menggunakan formula 10%, 20%, dan 30%. Ekstrak dibuat dengan metode perendaman menggunakan pelarut etanol 96%. Hewan uji pada penelitian rambut/bulu dicukur yang dimana akan diuji menggunakan 5 ekor tikus yang masing masing bulunya telah dicukur dengan ukuran 3x3 cm. Kelompok pertama (kontrol positif), kelompok kedua (kontrol negatif), kelompok ketiga (Shampoo Ekstrak Etanol Daun Cengkeh 10%), kelompok 4 (Shampoo Ekstrak Etanol Daun Cengkeh 20%) dan kelompok kelima (Shampoo Ekstrak Etanol Daun Cengkeh 30%). Parameter dalam penelitian ini adalah diameter sebagai pertumbuhan rambut. Hasil penelitian ini menunjukkan bahwa shampoo dari ekstrak etanol daun cengkeh dengan konsentrasi 30% adalah formulasi sediaan yang paling efektif dalam pertumbuhan rambut pada tikus jantan. Sediaan shampoo ekstrak etanol daun cengkeh kurang efektif dibandingkan dengan shampoo Clear pada pertumbuhan rambut
FORMULASI GEL MOISTURIZER DARI DAUN KELAKAI SEBAGAI UPAYA PEMBERDAYAAN TANAMAN LOKAL UNTUK KOSMETIK ALAMI MASYARAKAT DI DESA NAMORAMBE TAHUN 2025
Full text linkTanaman kelakai (Stenochlaena palustris) merupakan salah satu tanaman lokal yang juga tumbuh di lokasi sekitar masayarakat khusnya di desa namorambe yang memiliki potensi besar untuk dikembangkan sebagai bahan dasar kosmetik alami. Kandungan antioksidan dan senyawa aktif dalam daun kelakai menjadikannya cocok sebagai bahan pelembap sekaligus pelindung kulit dari paparan sinar matahari. Namun, pemanfaatannya dalam bentuk produk bernilai ekonomi masih sangat terbatas. Kegiatan ini bertujuan untuk memformulasikan gel moisturizer dari ekstrak daun kelakai dan memberikan penyuluhan serta pelatihan kepada masyarakat sekitar mengenai pembuatan produk kosmetik alami berbasis tanaman lokal. Metode pelaksanaan meliputi sosialisasi, pelatihan formulasi, dan uji kualitas sederhana terhadap produk yang dihasilkan. Hasil kegiatan menunjukkan bahwa masyarakat sangat antusias dalam mengikuti pelatihan dan mampu memproduksi gel moisturizer secara mandiri. Diharapkan, kegiatan ini menjadi langkah awal dalam pemberdayaan ekonomi lokal melalui pemanfaatan sumber daya alam yang berkelanjutan
FORMULASI SEDIAAN CREAM DAN UJI AKTIVITAS ANTIBAKTERI PADA EKSTRAK ETANOL KOMBINASI KULIT PISANG (Musa paradisiaca) DAN KULIT NANAS (Ananas comosus) TERHADAP BAKTERI PENYEBAB JERAWAT Propionibacterium acnes
Full text linkBackground: Acne vulgaris is a chronic inflammatory skin disease with a complex pathogenesis, involving sebaceous glands, follicular hyperkeratosis, bacterial overgrowth, immune and inflammatory responses. Objective: This formulate the ethanol extract of banana peel and pineapple peel into cream preparations and to test the effective antibacterial activity of the combination of banana peel and pineapple peel ethanol extract cream against Propionibacterium acnes. Methods: This research was conducted experimentally with maceration extraction using 70% ethanol as solvent. Acne cream is made with a concentration ratio between (Banana peel: Pineapple peel) namely F1 (Cream Base), F2 (5%:15%), F3 (7.5%:12.5%), F4 (10%:10% ), F5 (12.5%:7.5%), F6 (15%;5%), F7 (20%:0%) and F8 (0%;20%). Then, the physical stability test was carried out in the form of organoleptic test, viscosity test, pH test, homogeneity test, spreadability test and cream type test. Followed by testing the bacteria Propionibacterium acnes in Na media. Results: The antibacterial activity test on F3 showed that the diameter of 20.18 mm was relatively larger than F1 of 0mm, F2 of 18.63 mm, F4 of 18.38 mm, F5 of 16.48 mm, F6 of 18.28 mm, F7 of 13.91 mm and The F8 is 16.11 mm. Conclusion: Cream preparations from formula 1 to formula 8 the cream stability organoleptic test, viscosity test, pH test, homogeneity test, test spreadability and cream type test. The cream preparation in formula 3 has the widest diameter for antibacterial activity compared to other formulas
SOSIALISASI DAN EDUKASI KHASIAT DAUN TEH HIJAU (Camelia sinensis L.) DALAM SEDIAAN HAIR TONIC UNTUK PERTUMBUHAN DAN PERAWATAN RAMBUT DI DESA SUDIREJO KECAMATAN NAMORAMBE
Full text linkThis activity aims to educate the community in Sudirejo village about the efficacy of using hair tonic from herbal ingredients, namely from green tea leaves. Where green tea leaves have a strong polyphenol antioxidant content that can prevent hair loss, accelerate hair growth, and can maintain hair health nutrition. This activity involves pharmacists, This activity is expected to increase the understanding of the Sudirejo community about the efficacy of green tea leaves for hair health, and in this activity it is expected to provide information and learning to them about how to process and apply green tea leaves to hair so that people can make their own hair tonic preparations with green tea ingredients. The methods used include presentations, pre-tests and post-tests, interactive discussions, and distribution of educational materials. The results of observations showed an increase in participant awareness of the efficacy of green tea leaves after socialization. This study is expected to encourage hair health pattern
FORMULASI SEDIAAN HAIR TONIC EKSTRAK ETANOL DAUN TEH HIJAU (Camellia sinensis L.) SEBAGAI PENUMBUH RAMBUT TERHADAP KELINCI JANTAN (Oryctolagus cuniculus)
Full text linkBackground: hair loss is less or more hair than normal, with or without visible thinning. Green tea leaf minoxidil, whixh contains flavonoid compounds that may prevent hair loss, can be used to treat hair loss. Objective: this study aims to confirm whether green tea leaf ethanol extract can be used as a hair restorer that meets the requidments of physical stability, and to investigate the efficacy of green tea leaf extract hair restorer compared with minoxidil on hair growth purpose. Methods: This study used an experimental method that was macerated using 96% ethanol as a solvent. The formula was made into 3 concentrations, namely 2.5%; 5%; 7.5% compared with the drug minoxidil as a positive control. The three formulas were first evaluated to meet the requirements for hair tonic stability, then the hair effectiveness test was carried out with the test animal being a male rabbit. Results: the group that had the highest effectiveness on hair growth in rabbits was minoxidil which had an average value on the 7th, 14th and 21st days of 4.9 ; 6.3 ; 7.9 followed by the third formula which has a concentration of 7.5% as much as 4.5; 5.2 ; 6.5. While the negative control which was only applied with a hair tonic base only had hair growth 1,4; 1,9 ; 2,3. Conclusion: The preparation of hair tonic formula 1 to formula 3 met the requirements for physical stability, namely, pH test, viscosity test and organoleptic test. The preparation of hair tonic ethanol extract of green tea leaves (Camellia sinensis L.) showed that the 7.5% concentration was more effective in accelerating hair growth compared to formulas 1 and 2, and also showed that the 7.5% concentration had almost the same effectiveness as minoxidil (positive control)
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN KRIM BODY LOTION YANG MENGANDUNG EKSTRAK ETANOL AMPAS KOPI (Coffea arabica L.)
Full text linkBackground: The phenomenon of beauty as part of a woman's lifestyle, its existence has been felt since centuries ago. Body lotion is a cosmetic preparation in the form of a liquid emulsion that is used on the hands and body with the aim of moisturizing and softening the skin. Coffee grounds are a by-product of coffee processing. Coffee grounds contain a number of fatty acids, amino acids, polyphenols, minerals, polysaccharides and flavonoid compounds that function as a source of natural antioxidants. Purpose: to formulate and evaluate body lotion preparations of Coffea arabica L extract and to determine its effectiveness on dry skin. Methods: coffee grounds were extracted by maceration using 96% ethanol as solvent and concentrated with a rotary evaporator. Arabica L coffee extract was formulated with concentrations of 5%, 10%, and 15% using a body lotion base consisting of stearic acid, triethanolamine, mineral oil and aquadest. Evaluation of the quality of the preparations included homogeneity, viscosity, stability and pH during 4 weeks of storage. Examination of moisture content, number of pores and blemishes on the skin of volunteers was carried out every week for 4 weeks. Results: All body lotion preparations were homogeneous, stable during storage for 4 weeks, viscosity 3105-5180 cp, pH 6.9-7.3, and not irritating. Increased skin moisture, decreased pores and blemishes using a body lotion preparation with a concentration of 15% was the same as the positive control. All body lotion preparations with Coffea arabica L extract can increase skin moisture. Conclusion: The most effective body lotion formula that is treat dry skin namely the preparation with 15% Coffea arabica L concentration and not significantly different from the positive contro
PENYULUHAN PEMANFAATAN TANAMAN HERBAL DI LINGKUNGAN SEKITAR SEBAGAI OBAT TRADISIONAL DI SMA NEGERI 1 PANCUR BATU
Full text linkHerbal plants are plants that have been identified and known based on human observation to have compounds that are useful for preventing and curing disease. Traditional medicine is an ingredient or concoction of ingredients in the form of plant ingredients, animal ingredients, mineral ingredients, extract preparations (galenic), or mixtures of these ingredients which have been used for treatment for generations. Secondary metabolite compounds commonly found in plants are flavonoids, alkaloids, saponins, phenols, tannins, steroids and triterpenoids. Flavonoids are a group of polyphenols and are classified based on their chemical structure and biosynthesis. One of the plants that can be used as traditional medicine is the Sirih cina (Peperomia pellucida L. Kunth) . The aim of this counseling is to increase knowledge about the use of herbal plants and increase students' knowledge about traditional medicine in the surrounding environment as traditional medicine at SMA Negeri 1 Pancur Batu. After participating in this outreach activity, it is hoped that students will be able to increase their knowledge and level of health where students will be able to take part in educating friends and family regarding the importance of using medicinal plants as traditional medicine as an effort to maintain health by utilizing plants around them
UJI EFEKTIVITAS EKSTRAK ETANOL DAUN BANDOTAN (Ageratum conyzoides) SEBAGAI ANTIDIARE
Full text linkDiarrhea is an abnormal stool that is thinner than usual and occurs more than three times a day. Bandotan leaves have antibacterial properties. This study was an experimental study using 25 rats induced with oleumricin and divided into five groups, the negative control group of 1% CMC- Na, the positive control of Loperamide HCl and the group of bandotan leaf ethanol extract doses of 100 mg/kg, 150 mg/kg and 200 mg/kg. Bandotani leaves (Ageratum conyzoides) as samples were extracted by soaking using 96% ethanol then concentrated by spinning. The results of the phytochemical screening of bandotan leaves obtained flavanoid compounds, saponins, tannins, alkaloids. The results of the anti-diarrhea effect with EEDB doses of 100, 150 and 220 mg/kg showed an anti-diarrhea effect in male rats, the best anti-diarrhea effect was the average EEDB dose of 150 mg/kg. compared doses of 100 and 150 mg/kg. Bandotani leaf extract (Ageratum conyzoides) has antidiarrheal activity induced by oleumricin in male white rats
UPAYA MENGOPTIMALKAN EDUKASI SWAMEDIKASI DIARE PADA ANAK DI DESA RIMO MUNGKUR KECAMATAN NAMORAMBE KABUPATEN DELI SERDANG PROVINSI SUMATERA UTARA
Full text linkBackground: Self-medication is the selective use of modern and traditional medicine by individuals to treat disease. The pharmacist's role in this case is very important to ensure that patients receive appropriate, effective and safe medication and treatment in accordance with therapeutic goals. Aim: This service is to change people's mindset and perspective so that patients can better respond to information about children's diarrhea which can be done by themselves using the Cross-diarrhea Treatment Guidelines. Method: This service takes the form of Health Education in the pharmaceutical sector using a cross-sectional design method that explores risk factors and effects through an observational approach or collecting data at the same time. Results: This study shows that post-service patient knowledge about treating diarrhea in children and self-medication for diarrhea in children is superior in terms of correct use of medication, and in terms of correct and correct use of medication in daily life the patient has carried it out correctly. . Conclusion: The role of pharmacists regarding the suitability of self-medication for diarrhea using the Cross Diarrhea Guidelines is positive in providing knowledge and lessons for posyandu mothers in Rimo Mungkur Village, Namorambe Distric
- …
