17 research outputs found
Vaginal-assisted laparoscopic nerve sparing radical trachelectomy
No full textFertility-sparing surgery has gained popularity in the last three decades for the management of cervical cancer in women under 40 years of age. Radical trachelectomy is a fertility-sparing surgical technique for women who wish to retain their fertility. Vaginal-assisted laparoscopic radical trachelectomy is feasible in selected patients with early cervical cancer. The aim of this video is to present a nerve-sparing vaginal-assisted laparoscopic radical trachelectomy demonstrating pelvic anatomical structures
Robot-assisted laparoscopic transperitoneal infrarenal lymphadenectomy in patients with locally advanced cervical cancer by single docking: Do we need a backup procedure?
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Utilization of the Bologna criteria: a promise unfulfilled? A review of published and unpublished/ongoing trials
No full textPrenatal diagnosis of persistent left superior vena cava: a retrospective study of associated congenital anomalies
No full textWOS: 000462504300004PubMed ID: 31019836Objective: To evaluate persistent left superior vena cava (PLSVC) cases according to associated cardiac, extracardiac, and chromosomal anomalies in the prenatal period and to review their outcomes. Materials and Methods: The data of patients with a prenatal diagnosis of PLSVC between January 2013 and December 2017 were reviewed retrospectively. Results: Data of 32 cases were reviewed. Nineteen (60%) cases were associated with cardiac defects, 5 (15%) were associated with both cardiac and extracardiac defects, and 8 (25%) had no associated anomalies. Two fetuses had karyotype anomalies. All patients with isolated PLSVC survived. Among the cases associated with extracardiac anomalies, cardiac anomalies, and with both extracardiac and cardiac anomalies, the survival rate was 40%, 40%, and 25%, respectively. Outcome was more favorable in cases with isolated PLSVC (100% vs. 40%). Conclusion: Prenatally diagnosed PLSVC is associated with cardiac and extracardiac anomalies in the majority of cases. The prognosis is good in isolated cases, but worsens when accompanied by cardiac or extracardiac anomalies
Clermont-Ferrand versus Vectec uterine manipulator for total laparoscopic hysterectomy
No full textObjective: To compare the operation time and performance of two uterine manipulators used for total laparoscopic hysterectomy (TLH). Material and methods:Design: Retrospective cohort analysis. Design classification: Canadian Task Force Classification II-2. Setting: Tertiary-care university-based teaching hospital and academic affiliated private hospital. Patients: All consecutive patients who underwent for TLH between January 2014 and June 2017. All operations were performed by two expert endoscopic surgeons using one of the following uterine manipulators depending on surgeon preferences: Clermont-Ferrand (CF) or Vectec (VT) MAUT60. Patients were excluded if additional surgeries such as urogynecological procedures were performed, TLH was converted to laparotomy prior to colpotomy, and when their operation records could not be obtained. A total of 169 patients were added to final analysis. Operation time, colpotomy time and the subjective performance of manipulators such as movement of the uterus, visualization of the vaginal fornices, and maintenance of pneumoperitoneum were evaluated by watching un-edited operation videos. Results: A total of 169 patients (83 patients in CF group; 86 patients in VT group) were included in the final analysis. Patients’ baseline characteristics were comparable between groups. Operation time and time required for colpotomy were significantly shorter in the VT group. Lateral movements of the manipulators and elevation of the uterus were better with VT compared to CF (p = .001 for both). Compared to the CF, VT was superior for visualization of the vaginal fornices (p = .004) and maintenance of pneumoperitoneum (p p Conclusion: Laparoscopic hysterectomy assisted with the VT uterine manipulator is associated with shorter operation and colpotomy time. Furthermore, the movements of uterus, visualization of the vaginal fornices, and maintenance of pneumoperitoneum were significantly better with VT compared to the CF manipulator.</p
Mini-laparoscopy versus conventional laparoscopy for the management of endometrial cancer
No full textOBJECTIVE: We aimed to evaluate the feasibility of a mini-laparoscopic surgical approach versus standard laparoscopy. METHODS: 75 patients with endometrial cancer treated by mini-laparoscopic (n=25) or conventional laparoscopic surgery (n=50) at a tertiary-care university-based teaching hospital and academic affiliated private hospital were included. RESULTS: There was no significant difference between the mini-laparoscopy and the conventional laparoscopy group regarding surgical procedures. The mean operation time and the median estimated blood loss were similar (p=0.671 and p=0.158, respectively). No difference was found in terms of the number of lymph nodes removed. No intraoperative complications were observed in both groups. Return to daily routine and the rate of additional analgesia requirement were similar in the groups. The mean duration of hospitalization was 3.6±1.2 days in the mini-laparoscopy group and 4.9±3.6 days in the conventional laparoscopy group (p=0.025). CONCLUSION: We demonstrated that mini-laparoscopic staging could be a competent technique performed regardless of harm by talented surgeons using state-of-the-art instruments. Mini-laparoscopic surgery appears to be a further possibility to minimize surgical trauma by reducing the size of the ports without decreasing the extent and effectiveness of the procedures
Abstract 531: The cGAS-STING pathway as a driver of the immune-reactive microenvironment in small cell carcinoma of the ovary, hypercalcemic type
No full textAbstract 3780: Spatially resolved transcriptional patterns of PARP inhibitor-resistant high grade serous ovarian cancer PDX tissue
No full textAbstract 531: The cGAS-STING pathway as a driver of the immune-reactive microenvironment in small cell carcinoma of the ovary, hypercalcemic type
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