1,721,021 research outputs found
Autoimmune hyperthyroidism in two adolescents with DiGeorge/velocardiofacial syndrome (22q11 deletion)
Familial clustering of juvenile thyroid autoimmunity: higher risk is conferred by human leukocyte antigen DR3-DQ2 and thyroid peroxidase antibody status in fathers.
Adult height in short normal girls treated with gonadotropin-releasing hormone analogs and growth hormone.
Ectopic Intrathyroidal Thymus in Children: A Long-Term Follow-Up Study
Background: Ectopic intrathyroidal thymus has recently been reported in children as a cause of surgery and/or invasive diagnostic procedures when mistaken for a thyroid nodule. Thymus has a unique appearance at ultrasound (US). Methods: We report a follow-up study (mean 34 months, range 6-84) performed by US on 9 children (5 females) with a mean age of 6.3 +/- 3.2 years with intrathyroidal thymic inclusions diagnosed by US as 'incidentalomas'. None has palpable nodules. Results: Intrathyroidal thymic inclusions appeared on US as a hypoechoic area, with regular linear or punctuate internal hyperechoic echoes. The 2 oldest patients (13 and 17 years) showed a regression in both size and hypoechogenicity of thymic inclusions over time - reflecting the normal thymic involution with advancing age. Conclusions: Indeed, the lack of progression seen in our 9 patients over a mean time of 34 months confirmed the substantially benign and self-limited nature of this process. The increasing use of thyroid ultrasonography in children may result in an increased detection of intrathyroidal thymic inclusions - an embryologic anomaly that should be considered in the differential diagnosis of thyroid nodules in children and adolescents. Copyright (C) 2010 S. Karger AG, Base
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