1,721,014 research outputs found
Optic nerve involvement in diabetic retinopathy.
No full textThe Authors briefly review the problem of the involvement of optic nerve head in patients affected by diabetic retinopathy. It is suggested that optic nerve damage is always the result of a microvascular disorder involving the optic disc area. Diabetic papillopathy is considered in detail
Fluorescein angiography of the optic nerve head in the elderly.
No full textAbstract
Interpretation of fluorescein angiography of the optic nerve head is somewhat difficult due to its peculiar vasculature. Three early phases can commonly be observed: 1) retrolaminar and prelaminar filling; 2) prelaminar filling; 3) superficial capillary filling. The authors describe the characteristics of the fluorescein angiography of norman optic nerve hed in the elderly. The interpretation of these signs is also discussed
Macular distrophy, maternally inherited diabetes and deafness due to mutation of mitochondrial DNA
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EFFECTS OF IONIZING-RADIATION ON HUMAN CONJUNCTIVAL EPITHELIAL-CELLS - A CLINICAL AND CYTOLOGIC STUDY
No full textIn order to identify early and late modifications induced by ionizing radiation on the conjunctival surface, we studied 10 patients irradiated for paranasal sinus tumors. A clinical and morphological study of conjunctival epithelium (using an impression cytology technique) was performed; 5 patients were examined during and the others after treatment. Actinic conjunctivitis and keratitis, observed during treatment, reappeared within a few months after the end of radiotherapy. At a threshold dose of 25 Gy, chronic nuclear changes and cellular surface disorganization of the conjunctival epithelium were found - these progressed and persisted. Our data support the importance of careful monitoring of such irradiated patients and the benefit of planning a prospective clinical study to evaluate the effects of available drugs (all-trans retinoic acid) in the treatment of these lesions
Presumed ocular histoplasmosis in Europe: a case report.
Full text linkA case of presumed ocular histoplasmosis was diagnosed in a diabetic patient, and an angiographic study of the ocular lesions was carried out. Results of histoplasmin skin test and the specific complement fixation test were negative. The epidemiologic aspects of histoplasmosis in Europe are considered
Do oscillatory potentials and macular recovery time reflect metabolic control of diabetes mellitus?
No full textNot availabl
The role of fluorescein angiography in the interpretation of optic nerve head diseases.
No full textIn normal individuals fluorescein angiography of the optic nerve head has some peculiar signs. Three early phases can be distinguished, they include: 1) retrolaminar and laminar filling, 2) prelaminar filling, 3) superficial capillary filling. A late staining is also part of the fluorescein angiography of a normal disc. Many optic nerve disturbances show changes of the above mentioned angiographic signs. The Authors discuss the fluorescein angiographic pattern of 1) anterior ischemic optic neuropathy, 2) central retinal vein occlusion, 3) papilledema and 4) drusen
Sorsby's pseudo-inflammatory macular dystrophy: laser treatment]
No full textIn 1949, Sorsby described a familial fundus disease with progressive visual loss and bilateral hemorrhages and exudates of the posterior pole. The dystrophy, whose inheritance was apparently autosomal dominant, was called pseudo-inflammatory macular dystrophy because of extensive macular lesions that could suggest a post-inflammatory change. The ophthalmoscopic signs include the presence of diffuse drusen-like deposits with extensive changes of retinal pigment epithelium and focal atrophy of the choriocapillaris, particularly in the posterior pole. Some eyes grow subretinal neovascularization, which appears associated to retinal edema, deep hemorrhages and hard exudates. These cases ultimately result in a disciform macular scar. Atrophy of peripheral fundus is typical of advanced stages. We present the case of three sisters whose fundus lesions resembled Sorsby's pseudo-inflammatory macular dystrophy. In two of them, where there was a great suspicion of macular subretinal neovascularization, the laser treatment seemed to positively condition the course of the disease. In our opinion, even though a generalized atrophy of the choroid and retina cannot probably be avoidable, laser treatment can delay the loss of central vision, by blocking the capillaries from leaking, thus preventing secondary destruction from bleeding and fibrosis
(EURODIAB IDDM) Complications Study Group: Prevalence and management of hypertension in Type 1 diabetes mellitus in Europe.
No full textImpact Factor 2.17
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