173,755 research outputs found

    Hepatitis C virus infection: Review and implications for the dentist

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    The purpose of this report was to review the current literature on hepatitis C virus infection, with particular attention to the aspects of interest for dental health care staff

    How many individuals must be screened to reduce oral cancer mortality rate in the Western context? A challenge

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    OBJECTIVE: Controlling oral cancer (OC) through screening is appealing. Advantages of this are as follows: OC is often preceded by visible premalignant lesions, earlystage survival is threefold greater than late-stage survival, and visual screening is inexpensive. Disadvantages of this are as follows: high frequency of false positives, undemonstrated cost-effectiveness, and irregular screening attendance by high-risk individuals. Screening effectiveness in Western countries has not been proven, because of low OC prevalence, which disproportionally increases the number of individuals needed to screen (NNS) to decrease mortality. This study estimated the NNS to obtain an evident decrease in OC mortality rate in the UK. METHODS: Data gathered from reliable databanks were used. NNS to detect one case (NNScase) was estimated using a Bayesian approach. NNS to prevent one death (NNSdeath) was assessed multiplying NNScase by the number of cases that must be screen-detected to prevent one death. NNS to decrease mortality rate by 1% (NNSmortality) was assessed multiplying NNSdeath by 1% of annual OC deaths. RESULTS: NNSmortality was overall 1 125 000 (95% confidence interval – 95CI, 690 000–1 870 000), males 551 000 (95CI, 337 000–916 000), and females 571 000 (95CI, 347 000–942 000). CONCLUSIONS: An OC visual screening campaign capable of producing an evident decrease in mortality rate in the UK requires a large number of adults to be annually and regularly screened

    Release Rates for [t] in VCV Sequences Estimated from Aerodynamic Data

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    According to Stevens, "quantitative data must be obtained on rates of release and closure of articulators". Here, we use aerodynamic data in an orifice equation to estimate the rate of increase in the cross-sectional constriction area for [t] in different vowel contexts for 10 English speakers. Analyses of the results indicate that in most cases, the rate of release of [t] is significantly faster when an open vowel follows than when a close vowel follows

    An articulatory-acoustic-aerodynamic analysis of [s] in VCV sequences

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    Previous studies of the effect of vowel context on fricatives show seeming contradictions in the case of /s/: acoustic analysis shows the greatest context effect, while aerodynamic analysis shows relatively little effect, for the same subject. In this study, aerodynamic, acoustic, and articulatory data for the same subject producing /s, z/ in a variety of contexts were compared systematically. The strong acoustic effect of the /u - u/ context exists with /z/ as well as /s/, and appears to arise from a whistle-like source mechanism caused by lip rounding; the main tongue constriction does not appear to be immune to vowel context. Our interpretation of aerodynamic data as constrictions in series can be generalized to include the influence of lip rounding, thus: for this speaker and for these speaker-like sequences, the area of the vocal tract constriction for /s/ is independent of the vowel context but the overall aerodynamic effect does vary with lip rounding. Our aerodynamic and acoustic data seem to be consistent; both support the view that some rounding extends into the /s/ fricative
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