738 research outputs found

    commento agli artt. 18, 19 e 21 del Reg. 2016/679/UE

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    Commentario agli artt. 18 (diritto di limitazione di trattamento), 19 (obbligo di notifica in caso di rettifica o cancellazione dei dati personali o limitazione di trattamento) e 21 (diritto di opposizione) del Regolamento 2016/679/U

    Evaluation and prognostic significance of premature ventricular contractions in patients without structural heart disease

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    Introduction: Premature ventricular contractions (PVCs) are a common form of arrhythmia associated with poor prognosis in patients with structural heart disease. However, their prognostic impact on healthy individuals is unclear. There is also a lack of evidence about risk stratification of this group through cardiac imaging and electrocardiographic features. With this project we wanted to study whether patients with PVCs in which structural heart disease had thoroughly been excluded, have a worse prognosis than a control population. Moreover, we wanted to investigate whether PVC morphology and/or PVC duration are associated with the clinical outcome. Finally, we explored whether cardiac magnetic resonance imaging (CMR) and advanced echocardiographic parameters could unmask signs of structural heart disease in patients with high PVC-burden and normal echocardiogram.Methods: To study the prognostic impact of PVCs, we identified 807 patients with no history of structural heart disease, normal echocardiography and exercise test and verified PVCs. During a follow-up period of 5.2 years, we compared the clinical outcome–in terms of total mortality and cardiovascular morbidity–with a population matched by sex and age. To explore whether electrocardiographic features have a prognostic significance among healthy PVC-patients, we identified 541 patients to which we had access to PVC recording on 12-lead ECG and analysed PVC morphology and QRS width.For the studies focusing on diagnostic evaluation through advanced cardiac imaging, we included patients with a PVC burden of at least 10,000 beats/day and with normal results at exercise test and echocardiography. They underwent additional investigation with CMR (study 2) or advanced echocardiographic parameters that are normally not included in clinical praxis (study 3).Results: Healthy PVC-patients had a generally favourable prognosis, showing no worse clinical outcome than the sex- and age-matched control group that had not undergone investigation to rule out heart disease. However, patients with high PVC-burden showed signs of myocardial dysfunction when advanced imaging techniques were used, despite normal results at standard investigation that included echocardiogram.Sub-group analysis based on PVC-morphology showed that PVC originating from the outflow tract and the right ventricle was associated with a more favourable prognosis than intra cavity- and left ventricular PVCs respectively. Analysis of PVC-duration– measured as QRS-width during PVC–showed no impact on clinical outcome.Conclusions: PVC patients who had undergone a thorough medical examination with normal results did not have a worse outcome than matched controls during a median follow-up time of 5.2 years.PVC duration did not seem to be associated with the clinical outcome in our study including 541 patients with different sites of origin. However, PVCs with a morphology originating from the outflow tract and the right ventricle were associated with a better outcome.CMR and comprehensive advanced echocardiography could identify signs of myocardial dysfunction in patients with high PVC burden and normal findings at standard echocardiography. The clinical significance of these imaging findings needs to be assessed by larger longitudinal studies.List of scientific papersI. Scorza R.; Jonsson, M.; Friberg, L.; Rosenqvist, M.; Frykman, V. Prognostic implication of Premature Ventricular Contractions in patients without structural heart disease. EP Europace. 2022; euac184. https://doi.org/10.1093/europace/euac184 II. Scorza, R.; Jansson, A.; Sörensson, P.; Rosenqvist, M.; Frykman, V. Magnetic Resonance Detects Structural Heart Disease in Patients with Frequent Ventricular Ectopy and Normal Echocardiographic Findings. Diagnostics. 2021 Aug 20;11(8):1505, 11, 1505. https://doi.org/10.3390/diagnostics11081505 III. Scorza, R.; Shahgaldi, K.; Rosenqvist, M.; Frykman, V. Evaluation of patients with high burden of premature ventricular contraction by comprehensive transthoracic echocardiography. Int J Cardiol Heart Vasc. 2022 Sep 15;42:101124. https://doi.org/10.1016/j.ijcha.2022.101124 IV. Scorza, R.; Jonsson, M.; Corander, J.-M.; Rosenqvist, M.; Frykman, V. Prognostic impact of morphology and duration of Premature Ventricular Contractions in a population without structural heart disease. [Submitted]</p

    Corrado Cagli. Transatlantic bridges, 1938-1947

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    In the 1930s the young Italian artist, Corrado Cagli was a rising star of the Scuola Romana, supported by the Fascist regime despite being both Jewish and a homosexual. Following the Racial Laws, he fled first to Paris, and then to the USA, where he remained until 1947. Raffaele Bedarida’s new book, Corrado Cagli – La pittura, l’esilio, l’America (1938-1947) Donzelli Editore, 2018 (soon to be translated into English by CPL Editions), focuses on Cagli’s American exile. While examining Cagli in the context of the artistic and intellectual migration from Europe to the US, Bedarida provides valuable new insight into the specific plight of this Italian Jewish artist, once championed by Fascism and into the complexities of the use of art for cultural diplomacy. The author combines biography, cultural history, and critical analysis in exploring a decisive period in the life and work of a painter whose complex personality and non-signature style, defy classifications. The book also provides thought-provoking and nuanced arguments on the ideologically based ostracism that Cagli encountered upon returning to Italy in the immediate aftermath of the war. Because of his past as a former regime-endorsed artist, his recent American success, his participation in the liberation of Europe from Nazi-Fascism with the American army, and Jewish exile, Cagli simply did not fit into any of the faction of Italy’s post-war heated cultural disputes. Based on extensive original research and written with brio, Bedarida’s book is an essential contribution to a growing field of studies that examine how, by welcoming artist and intellectuals in flight from Nazi-Fascism, the United States had been given what Will Norman has called “custodianship for a civilization.

    Proceedings of the LREC 2020 workshop on Resources and Techniques for User and Author Profiling in Abusive Language (ResT-UP 2020)

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    This volume documents the Proceedings of the 1st Workshop on Resources and Techniques for User and Author Profiling in Abusive Language (ResT-UP), held online on 12 May 2020 as part of the LREC 2020 conference (International Conference on Language Resources and Evaluation). The workshop aimed at bringing together researchers and scholars working on author profiling and automatic detection of abusive language on the Web, e.g., cyberbullying or hate speech, with a twofold objective: improving the existing LRs, e.g., datasets, corpora, lexicons, and sharing ideas on stylometry techniques and features needed for profile information extraction and classification. ResT-UP targeted Profiling scholars and research groups, experts in Statistic and Stylistic Analysis of texts as well as computational linguists who investigate author profile and personality both in short texts (social media posts, blog texts and email) and in long texts (such as pamphlets, (fake) news and political documents). ReST-UP represented an opportunity to share profiling experiments with the scientific community and to show automatic detection techniques of abusive language on the Web. Despite the cancellation of LREC 2020 due to the COVID-19 international emergency, ResT-UP was organized online on Microsoft Teams on May 12th 2020 and the programme included three oral presentations and featured an invited talk by Paolo Rosso. ResT-UP was attended by about fifty representatives of academic and industrial organisations

    Commento all'art. 21 del Regolamento (UE) 2016/679 (regolamento generale sulla protezione dei dati)

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    Commento all'art. 21 del Regolamento (UE) 2016/679 e del decreto italiano di attuazion

    Slavo, romanzo, germanico. A proposito di alcune somiglianze e differenze nello sviluppo fonologico

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    Raffaele Caldarelli Slavic, Romance,Germanic: about some Similarities and Differences in Phonological Development In this paper the author aims at drawing a sketch of some aspects of the early Slavic phonological development, in terms of syllable structure, vocal quantity etc. The natural theory of syllabifi cation is taken into account as well as other factors. He tries also to shed some light on several controversial questions by a brief attempt at making a typological comparison between some aspects of phonological development in Slavic, Romance and Germanic languages. In this frame he discusses mainly some features of syllable structure in Romance and Germanic languages

    Commento art. 18 Regolamento (UE) 2016/679 (regolamento generale sulla protezione dei dati)

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    Commento all'art. 18 del Regolamento (UE) 2016/679 del 27 aprile 2016 (anche in considerazione del Decreto di adeguamento D.Lgs. n. 101/2018) che disciplina il diritto alla limitazione di trattamento dei dati personal
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