1,720,988 research outputs found
Airborne Contact Dermatitis® Due to Budesonide by Multiple Proxies
No full textA case of airborne contact dermatitis due to budesonide is reported and discusse
Systemic reaction to polycaprolactone‐based dermal filler: A case report
No full textWe present the case of an acute, severe diffuse adverse reaction to polycaprolactone-based dermal filler. To date, this is the first reported case in the literature
Dermoscopy of vulvar multiple syringomas: a diagnostic aid for a rare entity
No full textDermoscopy of vulvar syringomas shows peculiar features which can represent an excellent support for a non-invasive diagnosis. We report a paradigmatic case
Like Two Little Cowboys: Lucky Luke Dermatitis
No full textWe present 2 pediatric cases of allergic contact dermatitis due to the diaper; considering both clinical aspects and site involved, we diagnosed Lucky Luke dermatitis
Suffering and Quality of Life Impairment in Patients with Eczematous Diseases: Results from an Observational Study Assessing the Relevance of the Involvement of Two Sensitive Body Sites, Namely, the Face and Hands
No full textBackground: quality of life (QoL) impairment by eczematous diseases, with reference to body site involvement, has not been deeply addressed;Objectives: to assess: i) the impact on QoL of eczematous diseases affecting the face or hands; ii) any differences in QoL impairment in the case of face versus hands involvement; iii) sensitivity of Pictorial Representation of Illness and Self-Measure (PRISM) and Dermatology Life Quality Index (DLQI) in measuring disease-related burden; Methods: adults with eczematous diseases of the face or hands were involved. Patients were patch tested and underwent DLQI and PRISM;Results: 143 patients were included, 43.36% with face and 56.64% with hands involvement. PRISM and DLQI scores showed a moderate-to-strong inverse correlation, but PRISM revealed a higher sensitivity in capturing patients' suffering than DLQI, especially in the case of face involvement. Itching was the sole parameter significantly associated with both PRISM and DLQI scores. Conclusions: PRISM appeared to be more accurate in detecting the burden of eczematous diseases involving the face, probably due to the interception of the emotional impact, while DLQI, focusing on patient functioning, was more affected by hands involvement. Site involvement could be a criterion for selecting the best QoL assessment tool
Comparison of cancer risk between neutrophilic dermatoses and plaque psoriasis patients: a cancer registry-based study
No full textThis population-based, retrospective cohort study included all the patients who had received a histological diagnosis of either neutrophilic dermatoses or plaque psoriasis between 1995 and 2015 in the province of Ferrara, northern Italy. It was intended to assess the risk of cancer development based on the Ferrara Cancer Registry dataset.
The study cohort included 278 patients (51.8% males, age at diagnosis ranging from 9 to 93 years, median 54.5), of whom 52 (18.7%) were affected with neutrophilic dermatosis and 226 (81.3%) with plaque psoriasis. The whole cohort experienced a 31% global excess of cancer risk with respect to the age-matched general population living in the same area With respect to the main study objective, the increased cancer risk among patients with neutrophilic dermatoses
(SIR 1.35, CI 95% 0.7–2.4), when compared with the general population, did not differ significantly from that of patients with plaque psoriasis (SIR 1.30, CI 95% 0,9-1,8) both in univariate and multivariate Cox model.
Further studies are expected both to deepen the understanding of the relationship between these inflammatory skin diseases and cancer
Successful treatment of ectropion induced by actinic keratoses with photodynamic therapy: Report of two cases
No full textWe present two cases of ectropion induced by adjacent actinic keratoses which resolved with photodynamic therap
Urticaria: A Narrative Overview of Differential Diagnosis
No full textUrticaria is an inflammatory skin disorder that may occur in isolation or associated with angioedema and/or anaphylaxis. Clinically, it is characterized by the presence of smooth, erythematous or blanching, itchy swelling, called wheals or hives, which greatly vary in size and shape and last less than 24 h before fading to leave normal skin. Urticaria is the consequence of mast-cell degranulation that can be caused by immunological or non-immunological mechanisms. From a clinical point of view, many skin conditions can mimic urticaria and their recognition is mandatory for a correct management and therapeutic approach. We have reviewed all of the main relevant studies which addressed differential diagnosis of urticarial, published until December 2022. The National Library of Medicine PubMed database was used for the electronic research. The present review offers a clinical narrative overview, based on the available literature, of the principal skin disorders that can be misdiagnosed as urticaria (mainly autoinflammatory or autoimmune disorders, drug-induced reactions, and hyperproliferative diseases). The aim of this review is to provide clinicians a useful tool for correctly suspecting and identifying all of these conditions
Angioedema‐like contact dermatitis due to methylisothiazolinone in a mouthwash
No full textMethylisothiazolinone (MI) is an isothiazolinone derivative responsible for sensitization in about 9% of patients referred to patch tests. We report a case in which MI was responsible for an uncommon clinical manifestation, such as an angioedema-like contact dermatitis of the lips and oral cavity due to the use of a mouthwash
Effect of Corticosteroid Phobia on Treatment Adherence and Outcome in Women With Lichen Sclerosus: A Prospective Study
No full textObjective: The phenomenon of topical corticosteroid (TC) phobia (TCP) poses a challenge to the adherence of patients requiring prolonged treatments, particularly those with conditions like atopic dermatitis. Nonadherence to treatment significantly contributes to the inadequate control of diseases. This study aimed to evaluate TCP among women suffering from vulvar lichen sclerosus (VLS) and its potential impact on treatment adherence and therapeutic outcomes. Materials and Methods: This observational, prospective study involved adult patients who received their first histological diagnosis of VLS and underwent a 12-week corticosteroid treatment regimen at our Vulva Unit between June 2022 and September 2023. All participants completed the validated TOPICOP questionnaire, which assesses concerns, worries, and beliefs regarding TC usage. Baseline and 12-week control visit assessments were conducted to evaluate subjective and objective parameters of VLS. Patient adherence to treatment was monitored through diary entries. Results: Among the 50 patients included (with a mean age of 64.9 ± 13.5 years), more than half (58%) had prior experience with TC treatments and 10.3% had used corticosteroids for vulvar symptoms without a precise diagnosis. The median global TOPICOP score was 19.4% (interquartile range = 5.6–36.1), with a corresponding median value of 7.0 (interquartile range = 2.0–13.0). A total of 41 patients (82.2%) adhered to the study treatment, which proved highly effective in alleviating symptoms and improving signs of VLS. Multivariate analysis revealed that neither treatment adherence nor effectiveness were significantly associated with the level of TCP. Conclusions: Among our VLS patients, TCP was relatively low and did not negatively impact treatment adherence to corticosteroids. Moreover, TCP did not influence the effectiveness of TC therapy, as it did not affect adherence
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