1,087 research outputs found

    Developing a comprehensive conservation and management plan for the Palazzo Imperiale at Ostia Antica, Italy

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    The purpose of this paper is to outline the steps necessary for the development of a comprehensive conservation and management plan for the building known as the Palazzo Imperiale at Ostia Antica in Italy, utilizing a combination of the APPEAR method developed by Warnotte et al, and the values-based approach put forth by Demas. The current condition of the Palazzo is in a deteriorating state, and intervention will be necessary soon if the proposed plan is to be cost effective. Assessing the condition of the structure, its decorative elements (mosaics), its place within the Ostia Archaeological Park, and its future sustainable management will all be considered as components to a successful intervention at this site.M.A.Includes bibliographical referencesIncludes vitaby Todd E. Adam

    The ATP Tour with Todd Martin : A Lucrative Business

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    v, 139 p.The author interned as Small Business Manager for tennis pro, Todd Martin, responsible for transportation arrangements including: flight reservations and cancellations, and ground transportation, filing all the required expense reports and maintained the required documentation for all reported expenses. The author was also responsible for preparing Todd's six racquets for play, reserving practice courts, scheduling a practice partner, supervising his physical conditioning program, as well as such mundane tasks as laundry and grocery shopping, and whatever else Todd requested, or in some cases demanded. NOTE: pages 34-40 are missing.Missing pages 34-40

    Todd Siler : The Art of Thought

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    An attempt to define thought in physical terms initiated Siler's research in philosophy, the sciences and technology. The work resulting from these inquiries is an exploration of the knowledge, metaphors and artistic representations of human thought processes. Illustration of his paintings, collages and installations are accompanied by explanatory notes. Completing the catalogue are two reviews of his work as well as a text by the author on his concept of "neurocosmology". Biographical notes. Bibl. 4 p. Glossary

    Fast Evaluation of Generalized Todd Polynomials: Applications to MacMahon's Partition Analysis and Integer Programming

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    The Todd polynomials tdk=tdk(b1,b2,,bm)td_k=td_k(b_1,b_2,\dots,b_m) are defined by their generating functions k0tdksk=i=1mbisebis1.\sum_{k\ge 0} td_k s^k = \prod_{i=1}^m \frac{b_i s}{e^{b_i s}-1}. It appears as a basic block in Todd class of a toric variety, which is important in the theory of lattice polytopes and in number theory. We find generalized Todd polynomials arise naturally in MacMahon's partition analysis, especially in Ehrhart series computation. We give fast evaluation of generalized Todd polynomials for numerical bib_i's. In order to do so, we develop fast operations in the quotient ring Zp[[s]]\mathbb{Z}_p[[s]] modulo sd+1s^{d+1} for large prime pp. As applications, i) we recompute the Ehrhart series of magic squares of order 6, which was first solved by the first named author. The running time is reduced from 7070 days to about 11 day; ii) we give a polynomial time algorithm for Integer Linear Programming when the dimension is fixed, with a good performance.Comment: 24 pages, 1 figur

    Elevation of granulocyte colony stimulating factor in human AMD donor RPE-choroid

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    Purpose: choroidal inflammation, complement deposition, and accumulation of C-reactive protein (CRP) are involved in age-related macular degeneration (AMD) pathology. The pro-inflammatory signals that regulate immune cell recruitment in the choroid of patients with AMD remain to be determined. We performed cytokine profiling of human AMD and age-matched control donor tissue to identify inflammatory molecules upregulated in AMD tissue.Methods: protein was isolated from 25 AMD and 21 control donor RPE/choroid macular punches. Total protein was quantified, and 50 µg assayed for expression of 40 cytokines using an inflammation array. We validated the elevated expression of granulocyte colony stimulating factor (G-CSF) protein by ELISA in a second cohort of 22 control and 26 AMD donors. To identify an AMD associated stressor responsible for upregulating G-CSF we assayed for changes in G-CSF protein secretion in RPE/choroid organ cultures treated with the monomeric (m)CRP, an inflammatory protein elevated in AMD.Results: using a multiplex array, we identified elevated G-CSF protein in the choroid of AMD donors compared to age-matched non-AMD controls. Differential expression of G-CSF was confirmed via ELISA in an independent cohort of samples (P = 0.01). The mCRP, which is deposited in AMD choroids, increased G-CSF protein secretion in RPE/choroid organ cultures. Single nuclei RNA sequencing identified choroidal endothelial cells and fibroblasts as the primary cell types responsible for increased G-CSF secretion in response to mCRP. The G-CSF receptor is expressed primarily by choroidal macrophages and dendritic cells and anti-G-CSFR colocalizes with anti-CD45 and anti-CD68 in human donor choroid tissue.Conclusions: elevated G-CSF expression in AMD donor tissue as a result of increased levels of mCRP may be involved in immune cell recruitment in AMD contributing to inflammatory stress in the choroid

    I found it on the internet preparing for the e-patient in Oman

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    This research was originally published in SQUMJ. Author(s): Masters, Ken, Ng'ambi, Dick & Todd, Gail. Title: I found it on the internet preparing for the e-patient in Oman. SQU Med J (2010); 10(2): 169-79. © by Sultan Qaboos University Medical Journal.In the Information Age, the communication patterns between doctor and patient are changing. Using Everett Rogers' theory of Diffusion of Innovations, this paper begins by examining the diffusion of the Internet in the world and in Oman. It then considers the emergence of e-patients. The characteristics of e-patients are described in some detail. The paper ends by describing steps that should be taken when teaching medical students in Oman so that they can be prepared for e-patients

    Soft Ground : Ann Newdigate, Leslie Sampson, Ruth Scheuing, Barbara Todd

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    Marzolf notes the historical use of textiles to define and inculcate feminity, and as a site of resistance. The author examines each artist's use of dominant codes and political references. Biographical notes. 10 bibl. ref
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