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Indicatori di pregressa esposizione ad amianto
No full textAssessment of occupational and environmental asbestos exposure is based on measurement of
airborne asbestos fibre concentration as for other pollutants. Unfortunately, there is a lack of data
regarding many working sectors. Therefore, biomarkers of exposure can be often used effectively.
In particular this is true in the health surveillance of asbestos-exposed workers that should take
into account the intensity, latency and duration of exposure.
In practice identification of asbestos bodies and fibres in the lung tissue is possible in case of surgical
cancer resection or autopsy. Today in the diagnosis of asbestosis lung biopsy is almost never
practiced, because most cases of asbestosis are asymptomatic disease diagnosed radiologically.
Obviously, performing biopsy for study or legal purposes is not feasible.
Mineralogical analysis of bronchoalveolar lavage fluid (BALF) represents a method of considerable
utility for assessing asbestos exposure. This analysis includes the identification of asbestos bodies
by light microscopy and asbestos fibres by scanning or transmission electron microscopy. A number
of studies demonstrated that mineralogical analysis of BALF represents a reliable method for
assessing asbestos exposure even after many years from the end of exposure. Its use in the diagnosis
of asbestos-related diseases is generally accepted. The limits of the method is represented by
the considerable interlaboratory variation that makes it difficult to compare the results obtained in
different laboratories. For this reason, each laboratory should have its own reference values in order
to compare the results with data obtained with the same technique in exposed populations
and controls
Valutazione del rischio da amianto mediante determinazione dei corpuscoli e delle fibre nel liquido di lavaggio broncoalveolare
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Contributo allo studio del rischio da asbesto in operai e in soggetti non professionalmente esposti
No full textSpecie reattive dell’ossigeno indotte dall’addizione di sepiolite e vermiculite (espansa e non) a sospensioni di fagociti, polimorfonucleati umani e macrofagi alveolari bovini.
No full textPresenza di fibre di asbesto nel liquido di lavaggio broncoalveolare in soggetti non professionalmente esposti
No full textL'esperienza della medicina del lavoro senese nella sorveglianza sanitaria degli ex esposti ad amianto
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