2,310 research outputs found
Correlation Study between Laboratory Performance and Internship Grades of BS Information Technology and BS Computer Science Students in Lemery Colleges S.Y. 2021-2022
Abstract: The computer lab is very important to the student’s education. Every institution or university should have this as a key resource, especially for tech-related programs like BS Information Technology and BS Computer Science. The purpose of the study is to evaluate the connection between students with BSs in information technology and computer science's laboratory performance and internship grades. The main goal of the study is whether a student's success in the lab during their first year of college has an impact on how well they do in their practicum or internship. The descriptive-correlational study approach was used to demonstrate the laboratory performance of the SY 2021–2022 BSIT and BSCS graduating class. Performance indicators (PI) and the marks they got from the firms during their internships were used to demonstrate this performance. 35 graduates of the BS in information technology and 16 graduates of the BS in computer science from the academic year 2021–2022 are taking part in this study. It was concluded that there is a strong correlation between laboratory performance and academic internships under corporate supervision. These results contribute to a better significance of performance indicator assessment in laboratory procedures. The second goal is to raise the standards of the quality indicators used to evaluate and track students' computer lab performance. The research recommended integrating academic success and student output at work to create more meaningful data for quality improvement.
Keywords: Practicum, Correlation, Computer Laboratory, Performance Indicators.
Title: Correlation Study between Laboratory Performance and Internship Grades of BS Information Technology and BS Computer Science Students in Lemery Colleges S.Y. 2021-2022
Author: Rindel L. Noche, Lovelita D. De Ramos
International Journal of Computer Science and Information Technology Research
ISSN 2348-1196 (print), ISSN 2348-120X (online)
Vol. 11, Issue 1, January 2023 - March 2023
Page No: 39-41
Research Publish Journals
Website: www.researchpublish.com
Published Date: 10-February-2023
DOI: https://doi.org/10.5281/zenodo.7628761
Paper Download Link (Source)
https://www.researchpublish.com/papers/correlation-study-between-laboratory-performance-and-internship-grades-of-bs-information-technology-and-bs-computer-science-students-in-lemery-colleges-sy-2021-2022International Journal of Computer Science and Information Technology Research, ISSN 2348-1196 (print), ISSN 2348-120X (online), Research Publish Journals, Website: www.researchpublish.co
p73 and p63 regulate the expression of fibroblast growth factor receptor 3
p53, p63 and p73 make a family of transcription factors that play a vital role in development and cancer. All p53 family members have more than one promoter producing Transactivating (TA) and Dominant Negative (ΔN) isoforms and their mRNAs are subjected to extensive splicing at 3' end to produce multiple protein products. p53 is usually inactivated by point mutations during tumorigenesis, whereas the expression levels and p63 and p73 are modulated to give tumor cells a selective advantage. In this study, aiming to find novel targets of the p53 family members, we identified FGFR3 as a gene transcriptionally controlled by p63 and p73. FGFR3 has been implicated in development and tumor biology as activating mutations of this gene was described in skeletal disorders, non-invasive skin conditions and superficial bladder cancers. We found that TAp73, TAp63 and DeltaNp63 was capable of inducing FGFR3. siRNA mediated downregulation of DeltaNp63 decreased endogenous FGFR3 protein levels. Our findings of this new link between p53 family proteins and FGFR3 may help understanding the transition of superficial bladder cancers to an invasive phenotype
p73 and p63 regulate the expression of fibroblast growth factor receptor 3
p53, p63 and p73 make a family of transcription factors that play a vital role in development and cancer. All p53 family members have more than one promoter producing Transactivating (TA) and Dominant Negative (DeltaN) isoforms and their mRNAs are subjected to extensive splicing at 3' end to produce multiple protein products. p53 is usually inactivated by point mutations during tumorigenesis, whereas the expression levels and p63 and p73 are modulated to give tumor cells a selective advantage. In this study, aiming to find novel targets of the p53 family members, we identified FGFR3 as a gene transcriptionally controlled by p63 and p73. FGFR3 has been implicated in development and tumor biology as activating mutations of this gene was described in skeletal disorders, non-invasive skin conditions and superficial bladder cancers. We found that TAp73, TAp63 and DeltaNp63 was capable of inducing FGFR3. siRNA mediated downregulation of DeltaNp63 decreased endogenous FGFR3 protein levels. Our findings of this new link between p53 family proteins and FGFR3 may help understanding the transition of superficial bladder cancers to an invasive phenotyp
Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation article
Endometrial cancer is one of the most common gynaecological cancers in developed countries. Its incidence has increased 20% over the last decade and the death rate has increased >100% over the past two decades. Current models for prediction of prognosis and treatment response are suboptimal, and as such biomarkers to support clinical decision-making and contribute to individualised treatment are needed. In this study, we show that the E3-ubiquitin ligase PIR2/RNF144B is a potential targetable biomarker in endometrial cancer. At transcript level, it is expressed both in normal endometrium and tumour samples, but at protein level, it is expressed in tumours only. By using endometrial cancer cell lines, we demonstrated that PIR2/RNF144B is stabilised via phosphorylation downstream of GSK3β and this is necessary for the proliferation of endometrial cancer cells, in the absence of oestrogenic growth stimuli. Here, inactivation of GSK3β activity is associated with loss of PIR2/RNF144B protein and consequent inhibition of cell proliferation. Our results, therefore, substantiate PIR2/RNF144B as a novel candidate for targeted therapy in endometrial cancer.</p
P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis
The p73 protein, a member of the p53 family, has both developmental and tumorigenic functions. Here we show that p73 is cleaved by caspase-3 and -8 both in vitro and in vivo during apoptosis elicited by DNA-damaging drugs and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor ligation. TAp73 and some of its cleavage products are localized to mitochondria. siRNA-mediated downregulation of p73 expression induced a small but significant change in the susceptibility of HCT116 cells to TRAIL-induced apoptosis. A transcription-deficient mutant of TAp73 enhanced TRAIL-induced apoptosis suggesting that p73 protein has transcription-independent functions during death receptor-mediated apoptosis. Additionally, recombinant p73 protein induced cytochrome c release from isolated mitochondria providing evidence that nonnuclear p73 may have additional functions in the progression of apoptosis
Recommended from our members
Jetting, In-Nozzle Meniscus Motion and Nozzle-Plate Flooding in An Industrial Drop-on-Demand Print Head
The state of the ink film at and near the nozzles of a drop-ondemand(DoD) print head during jetting has a direct impact on
printing performance and reliability. We have developed highspeed imaging apparatus and analytical techniques to investigate
the ink film dynamics on an industrial print head nozzle-plate in real-time. In addition to a direct correlation between the jet
emergence velocity and drive voltage, drive-dependent variations in the oscillation of the ink meniscus in adjacent nozzles were also observed. Using a ray-tracing model to analyze the meniscus shape, the meniscus oscillations for both printing and nonprinting nozzles were found to be complex and involve elements such as pre-oscillation and high-order surface waves. The flooding of non-firing nozzles, deliberately caused by the application of maximum drive voltage to a neighboring nozzle, has been recorded and analyzed dynamically. The build-up of fluid in an annulus around the nozzle (flooding rate) has been characterized and compared with models for the net ink flow
through the nozzle
The microRNA and p53 families join forces against cancer
The product of the TP53 gene, p53, is one of the most recognised and extensively studied molecules that protects multicellular organisms from cancer. The well-deserved fame of p53 stems from the nature of its function – to coordinate an appropriate cellular response to various forms of genotoxic stress through cell cycle arrest, senescence and/or apoptosis. Given the importance of this role, it is not, perhaps, surprising that p53 was found to be inactive in more than half of human cancers. It should be noted that p53 does not work alone but cooperates with two ancestral proteins of the same family, p63 and p73. Aiming to broaden our understanding of the function of the p53 family of proteins in cancer, the mini-symposium held in the University of Leicester provided an opportunity for scientists and clinicians to exchange knowledge and expertise and to establish new collaborations. The main focus of this event was on the recently emerged link between the p53 family members and microRNA during cancer development
PhD, BS of Animal Science, and Faculty Member Based on Indonesia Education System
Academic degrees include PhD and BS of Animal Science -- Other. The author got these academic degrees based on Indonesia Education System, and according to the Minahasa culture or motto. However, the author got the degrees in the author's institution established by the author in 1984. The faculty member is in Animal Science -- Other
PhD, BS of Animal Science, and Faculty Member Based on Indonesia Education System
Academic degrees include PhD and BS of Animal Science -- Other. The author got these academic degrees based on Indonesia Education System, and according to the Minahasa culture or motto. However, the author got the degrees in the author's institution established by the author in 1984. The faculty member is in Animal Science -- Other
Search for LFV in Bs Decays
The flavor changing neutral current process is forbidden at tree level in the Standard Model (SM) and can only proceed via suppressed loop level diagrams.In the recent years, some deviation in the experimental measurements of Lepton Flavor Universality in B decays (i.e., b→ sℓℓ and b→ cℓν ) from the SM prediction and some theoretical models hint that there are lepton flavor violating interactions.Therefore, observation of the Lepton Flavor Violation (LFV) in B decays would be a clear signal of physics beyond the SM.We report herein the sensitivity study of Bs→ ℓτ(ℓ= μ, e) at Belle. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd
- …
