1,359,826 research outputs found
Effects of artificial stacking configurations and biaxial strain on the structural, electronic and transport properties of bilayer GaSe- A first principle study
No full textJoshna Palepu is thankful to UGC (Government of India) for PhD fellowship support through NET JRF. The work is supported by the Start-up Research Grant (SRG) by DST-SERB (Grant No. SRG/2020/000547) awarded to Sayan Kanungo
Sayan Banerjee’s contribution to the Discussion of “Root and community inference on the latent growth process of a network” by Crane and Xu
No full textSayan Banerjee’s contribution to the Discussion of
“Root and community inference on the latent
growth process of a network” by Harry Crane and
Min Xu
Sayan Banerjee
University of North Carolina, Chapel Hill
[email protected]
I congratulate the authors on their elegant and computationally tractable ap-
proach to inference problems in network archaeology. This is one of the few papers
which rigorously analyzes inference for noisy temporal networks. The key idea is
to compute the distribution of the possible arrival orders of vertices given an un-
labeled network realization (online detection) and construct the confidence set for
the root by sorting vertices according to their probability of arriving first given the
observed unlabeled network. A Gibbs type algorithm is provided to compute the
above distribution in O(m + n log n) time (m, n are, respectively, the number of
edges and vertices). Finally, some theoretical guarantees are provided for the size of
the confidence set provided the noise is not too large. I have the following comment
Tumour-promoting role of EMT-inducing transcription factor ZEB1 in mantle cell lymphoma
No full textEpithelial–mesenchymal transition (EMT) is an embryonic trans-differentiation programme that is implicated in organ formation by facilitating the formation of highly motile cells with stem cell capabilities. Most tissues of cells derived from ectoderm or mesoderm retain certain elements of EMT and mesenchymal properties are their differentiation markers. On the other hand, cells of organs derived from endoderm only experience EMT and its reversal (mesenchymal-epithelial transition) at certain phases of development and become differentiated secretory epithelial cells. As de-differentiation is a common feature of cancer progression, acquisition of mesenchymal markers accompanied with the loss of epithelial features can be observed in most carcinomas and considered as the reason of cancer spread (metastasis). For the reasons that (1) more than 85% of all cancers are of epithelial origin and (2) epithelial (differentiated) and mesenchymal (undifferentiated) carcinoma cells are morphologically very different, EMT has been mostly studied in carcinoma setting. However, there is growing evidence suggesting that cancers of organs derived from mesoderm (e.g., hematopoietic malignancies and sarcomas) or ectoderm (e.g., glioblastomas and melanomas) also activate EMT programs to acquire an undifferentiated state and become resistant to conventional therapies
Adverbs in Sayan Turkic
No full textThis paper focuses on the word class "adverb" in Sayan-Turkic - a small Turkic language group of South Siberia - presenting data from the official languages Tuvan and Tofan and from the Sayan varieties spoken in Mongolia and China
Assessment of the thermal pyrolysis characteristics and kinetic parameters of spent coffee waste: a TGA-MS study
No full textThe present study aimed to investigate the pyrolysis characteristics and kinetics of spent coffee waste (SCW) at different heating rates (5-40 degrees C/min) at a temperature ranging from 30 to 800 degrees C in a thermogravimetric analyzer (TGA). First, the physicochemical properties of the SCW were characterized using X-ray diffraction, Fourier transform infrared spectrometry, scanning electron microscopy, and elemental analysis. Then, the thermal decomposition kinetic profiles were modeled using the Coats-Redfern, Flynn-Wall-Ozawa (FWO), Kissinger-Akahira-Sunose (KAS), and Starink models. All the tested models provided accurate fits of the thermogravimetric analysis data with acceptably high R-2 values. The mean activation energy of the coffee waste was 101.8, 96.7, and 97.1 kJ/mol for the FWO, KAS, and Starink models, respectively. Finally, the evolved gases detected during the decomposition by TGA coupled with a mass spectrometer (MS) primarily consisted of water, methane, and carbon dioxide
Oxygen and Hydrogen Isotope Compositions of Lithalsa Frozen Core: A Case Study from the Sentsa River Valley, East Sayan
No full textMineral permafrost mounds (lithalsas) have been studied in the Sentsa River valley (East Sayan Mountains, western Buryatia). This is the first detailed study of permafrost in the area based on analysis of cryostructures and distribution of stable isotopes in lithalsa intrusive-segregation ice. The lithalsas predominantly have reticulate or lenticular cryostructures and ice contents over 50-60 %. The lateral and vertical δ¹⁸O and δ²H patterns suggest cascade growth with the large lithalsa formed before the small one. Lithalsas can nucleate and grow during progressive lake shallowing. They feed mainly from ground water during freezing of wet frost-susceptible finegrained soil, or less often, from meteoric or lake water. Lithalsas grow quite rapidly, at tens of centimeters per year, and can reach more than 5 meters high in 50-100 years
GEOCHEMISTRY AND ORIGIN OF THE EASTERN SAYAN OPHIOLITES, TUVA-MONGOLIAN MICROCONTINENT (SOUTHERN SIBERIA)
No full textThe Eastern Sayan ophiolites (1020 Ma) of the Tuva-Mongolian microcontinent are believed to be the most ancient ophiolite of the Central Asian Orogenic Belt [Khain et al., 2002].The Eastern Sayan ophiolites (1020 Ma) of the Tuva-Mongolian microcontinent are believed to be the most ancient ophiolite of the Central Asian Orogenic Belt [Khain et al., 2002]
Dr. César Delgado Sayan
No full textPeriodo de publicaciónIntegridad completaBuen estado de conservaciónDigitalización realizada por Wendy Ochoa Alvarez.Dr. En la fotografía se reconoce de pie a César Delgado Sayan dando un discurso
p73 and p63 regulate the expression of fibroblast growth factor receptor 3
No full textp53, p63 and p73 make a family of transcription factors that play a vital role in development and cancer. All p53 family members have more than one promoter producing Transactivating (TA) and Dominant Negative (ΔN) isoforms and their mRNAs are subjected to extensive splicing at 3' end to produce multiple protein products. p53 is usually inactivated by point mutations during tumorigenesis, whereas the expression levels and p63 and p73 are modulated to give tumor cells a selective advantage. In this study, aiming to find novel targets of the p53 family members, we identified FGFR3 as a gene transcriptionally controlled by p63 and p73. FGFR3 has been implicated in development and tumor biology as activating mutations of this gene was described in skeletal disorders, non-invasive skin conditions and superficial bladder cancers. We found that TAp73, TAp63 and DeltaNp63 was capable of inducing FGFR3. siRNA mediated downregulation of DeltaNp63 decreased endogenous FGFR3 protein levels. Our findings of this new link between p53 family proteins and FGFR3 may help understanding the transition of superficial bladder cancers to an invasive phenotype
ECOLOGY OF CHIROPTERA BATS IN ALTAI-SAYAN REGION OF SOUTHERN SIBERIA
No full textAim. The aim of this work is to summarize the available data on zoogeographic analysis and fauna of the bats of the Altai-Sayan region.Discussion. The chiropterofauna of the AltaiSayan highlands includes the representatives of 13 species. The obtained data on the distribution of bats in the region made it possible for the first time to carry out a zoogeographic analysis of the chiropterofauna of the Altai-Sayan highland. The faunal complex of bats in the study area and adjacent territories is represented by boreal, European and Central Asian species. The cluster analysis by Jaccard coefficient allowed us to distinguish two main chiropterological complexes: Altai-Sayan and Ubsunur. Our boundary between these complexes coincides or is close to the biogeographic boundaries drawn for various groups of vertebrates and invertebrates, as well as plants.Conclusion. Altai-Sayan territory is inhabited by 13 bat species of six genera belonging to Vespertilionidae family. The most common species are the following: eastern water bat – Myotis petax Hollister, 1912; Siberian bat – Myotis sibiricus Kastschenko, 1905; Ikonnikov's bat – Myotis ikonnikov Ognev, 1912; Northern bat – Eptesicus nilssonii Keyserling, Blasius, 1839; Parti-coloured bat – Vespertilio murinus Linnaeus, 1758; Ognev's long-eared bat – Plecotus ognevi Kishida, 1927. In the fauna of the region, the boundary between two chiropterological complexes (Altai-Sayan and Ubsunur) runs through Kurtushibinsk-Usinsk province
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