62 research outputs found

    sj-pdf-1-neu-10.1177_19714009211049080 - Supplemental material for Acquired pial arteriovenous fistula secondary to cerebral cortical vein thrombosis: A case report and review of the literature

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    Supplemental material, sj-pdf-1-neu-10.1177_19714009211049080 for Acquired pial arteriovenous fistula secondary to cerebral cortical vein thrombosis: A case report and review of the literature by Skander Sammoud, Nadia Hammami, Dhaker Turki, Fatma Nabli, Samia Ben Sassi, Samir Belal, Cyrine Drissi and Mohamed Ben Hamouda in The Neuroradiology Journal</p

    Supplemental material for Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region—Results from the Safe Implementation of Treatments in Stroke (SITS)–Middle-East and North African (MENA)

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    Supplemental Material for Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region—Results from the Safe Implementation of Treatments in Stroke (SITS)–Middle-East and North African (MENA) by Suhail Al Rukn, Michael V Mazya, Faycal Hentati, Samia Ben Sassi, Fatma Nabli, Zakharia Said, Belahsen Faouzi, Husnain Hashim, Foad Abd-Allah, Benhan Mansouri, Selma Kesraoui, Souheil Gebeily, Husen Abdulrahman, Naveed Akhtar, Niaz Ahmed, Nils Wahlgren, Hany Aref, Mohammed Almekhlafi and Tiago Moreira: for the Stroke Emergency Mobile (STEMO) Consortium in International Journal of Stroke</p

    Estudio de los personajes míticos, exóticos y sobrenaturales en las leyendas orientales de Gustavo Adolfo Bécquer

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    Study of the Mythical, Exotic and Supernatural Characters in the Oriental Legends of Gustavo Adolfo Bécquer ABSTRACT: This article aims to shed light on different crossings, interferences, interculturalities   and considerable literary evolution between East and West, that was inherited from remote times creating an influence which look like a pearl necklace where the first pearl complete the next one. Spanish literature has always been inspired by traditional oriental Arabic poetry such as the Qasidah, located in the Andalusian historical past that had its roots in the pre-Islamic Arabic literature of the Jahiliya.  In order for this influence to be justified, we have focused on the legends of Gustavo Adolfo Bécquer, from Seville author inspired by Eastern mythology, especially Arabic and Hindu that he adopted, thanks to his readings of authors such as Conde de Noroña (1760-1816). Famous with his book Asiatic Poems (1833) that opened the taste for what is exotic and for what is oriental. That romanticists like Bécquer used to feed their imaginations creating legendary, exotic, supernatural and, above all, mythical characters from Arab and Hindu mythology, creating, in this way, simultaneously a great diversity and richness of themes nourished by traditions and distant beliefs. RESUMEN: Este artículo tiene como objetivo arrojar luz sobre distintos cruces, interferencias, interculturalidades y evolución literaria considerable entre Oriente y Occidente que se heredó desde tiempos remotos creando una influencia que se asemeja a un collar de perlas donde la primera perla llama a la siguiente. La literatura española siempre se inspiró en la poesía árabe tradicional oriental tal como la qasidah, ubicada en su pasado histórico andaluz que tuvo su raíz en la literatura preislámica árabe del Yahiliya. Para que quede justificada esta influencia, nos hemos focalizado en las leyendas de Gustavo Adolfo Bécquer (1836-1870), un autor sevillano inspirado en la mitología oriental, en especial, árabe e hindú que adoptó gracias a sus lecturas de autores como Conde de Noroña (1760-1816) célebre por su libro Poesías asiáticas (1833), que abrió el gusto por lo exótico y lo oriental, que los romanticistas como Bécquer se sirvieron para alimentar sus imaginaciones creando personajes legendarios, exóticos, sobrenaturales y, sobre todo, míticos de la mitología árabe e hindú, creando, de esta manera, simultáneamente una  gran diversidad y riqueza temáticas nutridas de tradiciones y creencias lejanas.

    Increased T-bet/GATA-3 and ROR-γt /Foxp3 Ratios in Cerebrospinal Fluid as Potential Criteria for Definite Neuro-Behçet’s Disease

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    When the central nervous system (CNS) is the primary affected site in an initial attack of Behçet’s disease (BD), the differential diagnosis is particularly challenging. Some cases remain unclassified or qualified as probable neuro-Behçet’s disease (NBD). Several cytokines are involved in the immunopathogenesis of this disease; however, studies establishing the differential cytokine pattern between probable and definite NBD are scarce. Twenty-eight parenchymal NBD patients, diagnosed according to the International Consensus Recommendation (ICR) criteria and classified into definite (D-NBD; n = 17) and probable (P-NBD; n = 11), were sampled at their first neurological symptoms, and compared with healthy control subjects (n = 20). Oligoclonal bands (OCB) of IgG were detected by isoelectric focusing on agarose, and immunoblotting of matched serum and cerebrospinal fluid (CSF) sample pairs. T cell cytokines (INF-γ, IL-4, IL-17, and IL-10) and transcription factors related to Th1, Th2, Th17, and T regulatory populations (respectively T-bet, GATA-3, ROR-γt, and Foxp3) were studied by quantitative RT-PCR in peripheral blood mononuclear cells (PBMCs) and CSF cells. Inflammatory cytokines such as IL-6, TNF-α, and IL-1β were also analyzed. CSF OCB pattern 2 was present in only 1 out of 28 neuro-Behçet’s patients who belonged to the P-NBD group. Two D-NBD patients had OCB in CSF showing pattern 4. In the D-NBD CSF samples, IL-17 and IL-10 expressions were significantly elevated compared to P-NBD. Moreover, D-NBD patients had increased levels of T-bet/GATA-3 and ROR-γt/Foxp3 ratios compared to P-NBD. Furthermore, a significant increase of CSF IL-6 in D-NBD, compared to P-NBD and the controls, was found. In addition to the increased IL-6 level, the data obtained suggest the existence in D-NBD patients of a significantly disrupted balance between Th17 effector and T regulatory cells, as reflected by the enhanced ROR-γt/Foxp3 ratio. This could be considered as an additional criterion for definite neuro-Behçet’s disease

    LEAN DESIGN IN CONSTRUCTION INDUSTRY: FROM THEORY TO PRACTICE

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    This paper provides a literature review of over 70 published research articles regarding Lean Design from 2002 to 2018. The review focuses on two aspects. Firstly, it provides a comparison between different definitions and terminologies presented by authors, and secondly gives an analysis of how Lean Design methods/tools apply to the construction industry. Two main issues have been identified and explored in this review. Indeed, there is still a gap between theory and practice concerning the context of the construction industry which makes the implementation process effortful and not clear for the practitioners. One aspect of this gap is reflected by the lack of a standard definition of what Lean Design means. Another aspect is the lack of consensus on a clear terminology of Lean Design. Definitions and interpretations differed from an author to the other with little emphasis on value. Besides, there is a lack of coherence between the proposed Lean Design definitions and the methods/tools used in practice. Thus, the first contribution of this research is providing a better comprehension of current Lean Design literature in the construction sector. The second one consists of presenting the different Lean Design definitions perspectives, and the incoherencies between these perspectives and the methods/tools proposed. Moreover, the last contribution is providing a new Lean Design definition taking into account abovementioned.info:eu-repo/semantics/publishe

    The Evolution of Genetic Variability at the LRRK2 Locus

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    Leucine-rich repeat kinase 2 (LRRK2) c.6055G&gt;A (p.G2019S) is a frequent cause of Parkinson&rsquo;s disease (PD), accounting for &gt;30% of Tunisian Arab-Berber patients. LRRK2 is widely expressed in the immune system and its kinase activity confers a survival advantage against infection in animal models. Here, we assess haplotype variability in cis and in trans of the LRRK2 c.6055G&gt;A mutation, define the age of the pathogenic allele, explore its relationship to the age of disease onset (AOO), and provide evidence for its positive selection
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