1,790 research outputs found

    R19. Investigation of Taste Masking Efficiency of Caffeine Citrate by Lipids Utilizing Hot Melt Extrusion Technology

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    Corresponding author (Pharmaceutics and Drug delivery): Priyanka Srinivasan, [email protected]://egrove.olemiss.edu/pharm_annual_posters/1018/thumbnail.jp

    Tidal bores, catastrophic flooding in Bangladesh, and the potential usefulness of causeways

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    Through discussion of the worldwide devastation that tidal bores can cause, author Priyanka Joseph, examines the causes and the possible solutions to prevent these destructive waves. The pros and cons of each solution (such as causeways, viaducts, and regulators) are debated as well as their effect on the surrounding areas and environment

    First Results of a Campaign of the Measurement of Polycyclic Aromatic Hydrocarbons in the Sediments of the Hooghly River, West Bengal, India

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    This study presents the first data on a 2018–2021 campaign to monitor polycyclic aromatic hydrocarbon levels, PAHs, in the final stretch of the Hooghly River in West Bengal, India. The range of sedimentary PAHs was 0–47,366 ng/g, higher than the ranges given by the literature for comparable study areas. The assay reveals an outstanding level of PAHs contamination in the fine sediments of the Hooghly River and Sundarban wetland, where the dominance of 4–6 ring PAHs was 83% of the total. The diagnostic ratios based on molecular ratios of PAHs show that the pollution comes mainly from the combustion of petroleum. The ratio of anthracene relative to anthracene plus phenanthrene, ANT/(ANT + PHE), was >0.30, which is higher than the reference discriminant ratio of >0.10, suggesting that PAHs were from the combustion source. In the meantime, fluoranthene over the sum of fluoranthene plus pyrene, FLT/(FLT + PYR), was >0.5 and indicated coal combustion, in agreement with the literature. The mean level of carcinogenic hydrocarbons was at 18% of the total measured PAH, with a peak of 91%, revealing significant potential risk for humans and ecosystems. The toxicity equivalence factors, TEF, of the individual PAHs and the total BaP equivalent toxicity, TEQ, were adopted as a comparison reference of sediment quality. At most sites, toxic effect ranges were classified as high and very high. The results of this research call for public authorities to remedy a situation of severe ecological risk

    A Recipe for Brown Stew

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    By Geeta Budhraja This is the apéritif to what I hope can translate into a larger comprehensive project on the delights of Anglo-Indian cuisine. Born into a family where conversations celebrated food – what to eat, why, the origin of the dish or ingredients, etc. – and a healthy inclination towards fusion, it’s not surprising that Anglo Indian cuisine is by far my all-time favourite. Image courtesy of Ms. Priyanka Sarkar.   My paternal grandfather was Chief Engineer with the Indian Railways..

    Distributed human computation framework for linked data co-reference resolution

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    Distributed Human Computation (DHC) is a technique used to solve computational problems by incorporating the collaborative effort of a large number of humans. It is also a solution to AI-complete problems such as natural language processing. The Semantic Web with its root in AI is envisioned to be a decentralised world-wide information space for sharing machine-readable data with minimal integration costs. There are many research problems in the Semantic Web that are considered as AI-complete problems. An example is co-reference resolution, which involves determining whether different URIs refer to the same entity. This is considered to be a significant hurdle to overcome in the realisation of large-scale Semantic Web applications. In this paper, we propose a framework for building a DHC system on top of the Linked Data Cloud to solve various computational problems. To demonstrate the concept, we are focusing on handling the co-reference resolution in the Semantic Web when integrating distributed datasets. The traditional way to solve this problem is to design machine-learning algorithms. However, they are often computationally expensive, error-prone and do not scale. We designed a DHC system named iamResearcher, which solves the scientific publication author identity co-reference problem when integrating distributed bibliographic datasets. In our system, we aggregated 6 million bibliographic data from various publication repositories. Users can sign up to the system to audit and align their own publications, thus solving the co-reference problem in a distributed manner. The aggregated results are published to the Linked Data Cloud

    Cenchrus ciliaris RepeatExplorer Priyanka Rathore, Bhat, Schwarzacher, Heslop-Harrison, Tomaszewska

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    The repetitive DNA sequence landscape and DNA methylation in chromosomes of an apomictic tropical forage grass, Cenchrus ciliaris Abstract RepeatExplorer supplementary data for manuscript:    Priyanka Rathore1, Paulina Tomaszewska[H(1] [ST(2] 2,3, Trude Schwarzacher2,4, J.S. (Pat) Heslop-Harrison2,4,* and Vishnu Bhat1 1)Department of Botany, Faculty of Science, University of Delhi,  Delhi, India 2)Department of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, United Kingdom 3)Department of Genetics and Cell Physiology, Faculty of Biological Sciences, University of Wrocław, 50-328 Wrocław, Poland 4)Key Laboratory of Plant Resources Conservation and Sustainable Utilization / Guangdong Provincial, Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China *)Corresponding author. E-mail: [email protected] and [email protected] Cenchrus ciliaris is an apomictic, allotetraploid pasture grass widely distributed in tropical and subtropical regions of Africa and Asia. In this work, we aim to investigate the genomic organization and characterize the nature of repetitive DNA sequences in this species. Because of the apomictic propagation, various aneuploid genotypes are found and we analysed here a 2n=4×+3=39 accession. The physical mapping of Ty1-copia and Ty3-gypsy retroelements through fluorescence in situ hybridization with global assessment of 5-methylcytosine DNA methylation through immunostaining revealed the genome-wide distribution pattern of retroelements and their association with DNA methylation. About a third of Ty1-copia sites overlapped or spanned centromeric DAPI positive heterochromatin, while the centromeric regions and arms of some chromosomes were labeled with Ty3-gypsy. Most of the retroelement sites overlapped with 5-methycytosine signals, except some Ty3-gypsy on the arms of chromosomes which did not overlap with anti-5-mC signals. Universal retrotransposon probes did not distinguish genomes of C. ciliaris showing signals in pericentromeric regions of all 39 chromosomes, unlike highly abundant repetitive DNA motifs found in survey genome sequences of C. ciliaris using graph-based clustering. Developed Cluster probes gave strong signals mostly in pericentromeric regions of about half of the chromosomes, and we suggested that they differentiate the two ancestral genomes in the allotetraploid C. ciliaris likely having different repeat sequence variants amplified before the genome came together in the tetraploid. </p
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