4 research outputs found
The role of real options in the takeover premia in mergers and acquisitions
No full textThis paper applies a real option framework to suggest that the takeover premia in mergers and acquisitions can be influenced by (a) the pre-bid ownership of target and (b) the real option characteristics of both acquirer and target firms. Our findings show that pre-bid ownership reduces the takeover premia, which is consistent with the argument that pre-bid ownership reduces information asymmetry. However, we find that the takeover premia is higher when both the acquirer and target firms exhibit real option capacity as measured by positive risk-return sensitivity. As a result, an acquirer with real option capacity is willing to pay higher takeover premia for an option embedded in the target firm
Chinese mothers - Western daughters? : cross-cultural representations of mother-daughter relationships in contemporary Chinese and Western women's writing
No full textThis study looks at women's prose narrative representing four major
Chinese communities during the last 30 years, and focuses on the depiction of
mother-daughter relationships among personae within the narrative texts. The
thesis seeks to suggest that mother-daughter relationships within the texts are a
reflection of how a text responds to its mother culture in the course of development.
Narrative prose ranging from self-professed autobiographies to the fictional,
written by Chinese women from American-Chinese communities, Hong Kong,
Taiwan and Mainland China, are examined in a comparative approach within an
ethnical framework. The concept of a national literature is discussed with regard to
different fonns of Chinese-ness.
It is revealed, in the course of this examination, that each group of Chinese
women's writing examined here demonstrates an acute awareness of a link with an
original mother culture, the Chinese orientation. However, recent events both
inside and outside China have inevitably shaped cultural development in these
communities, resulting in splits and diversifications in the individual cultural
consciousness.
Approached from this perspective, the Chinese mother culture gains a new
vitality by virtue of shedding the burden of a long history. Focusing on the
intertextual activities of regional writings, it is shown that represented Chinese-ness
is no longer an unchanged and unchanging phenomenon, but is redefined each
moment through the locus of interactions among independent hybrid communities
Solanum nigrum L. subsp. schultesii (Opiz) Wessely (BR0000010042663)
No full textBelgium Herbarium image of Meise Botanic Garden
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
No full textBackgroundTranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding.MethodsWe did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124.FindingsBetween July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98).InterpretationWe found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial.</div
