537 research outputs found
Christina Gillis, author of Writing on Stone: Scenes from a Maine Island Life,
No full textChristina Gillis, author of Writing on Stone: Scenes from a Maine Island Life, delves into old letters written by Maine writer Ruth Moore in the 1950s. Moore was selling her family\u27s Gotts Island house to Phyllis and Richard Strauss, Gillis\u27s sister and brother-in-law
The 'true use of reading' : Sarah Fielding and mid eighteenth-century literary strategies.
No full textPhDThe aim of this thesis is to explore, by examining her life and
works, how Sarah Fielding (1710-68) established her identity as an author.
The definition of her role involves her notions of the functions of
writing and reading.
Sarah Fielding attempts to invite readers to form a sense of ties
by tacit understanding of her messages. As she believes that a work
of literature is produced through collaboration between the writer and
the reader, it is an important task in her view to show her attentiveness
toward reading practice. In her consideration of reading, she has two
distinct, even opposite views of her audience: on the one hand a familiar
and limited circle of readers with shared moral and cultural values and
on the other potential readers among the unknown mass of people. The
dual targets direct her to devise various strategies. She tries to
appeal to those who can endorse and appreciate her moral values as well
as her learning. Her writings and letters testify that she is sensitive
to the demands of the literary market, trying to lead the taste of readers
by inventing new forms.
The thesis opens with an overview of Sarah Fielding's career,
followed by a consideration of her critical attention to the roles of
reading. I go on to examine the narrative structures and strategies
she deploys, with a particular emphasis on her use of the epistolary
method. The following chapter deals with her attention to the reading
of the moral message tangibly embodied in her educational writing. It
is followed by an analysis of the activity which earned her a reputation
as a learned woman. Various as the forms of her works are, they invariably
reflect her attempt to balance herself between the two demands of
inventiveness and familiarity
A Looking Forward: Phil's Final Weeks
No full textAlexandra Gillis is a teacher and educational researcher living in the city of Vancouver, on the territorial lands of the Musqueam, Squamish and Tsleil-Waututh peoples, amidst mountains and ocean of Canada’s west coast. She has published Thinking Woman (2006) and is co-author, with John Benton and Philip McShane, of Introducing Critical Thinking (2005). She currently works for the Ministry of Education
Excitation-contraction coupling in fish cardiomyocytes
No full textExcitation of the fish cardiac myocyte with an action potential causes intracellular Ca2+ levels to rise, which initiates contraction. This sequence of events is termed “excitation-contraction coupling”. Cardiomyocytes contract when intracellular Ca2+ concentrations rise and Ca2+ binds to the contractile element, the cellular machinery responsible for powering the contraction. This binding allows the formation of cross-bridges between the actin thin filament and the myosin thick filament under the regulation of the troponin complex (troponin I, troponin T, and troponin C) and tropomyosin. To end contraction and begin relaxation, Ca2+ levels inside the myocyte must fall. The Ca2+ transient is the rise and fall of Ca2+ with each contraction-relaxation cycle. In fish, the Ca2+ fluxes which generate the Ca2+ transient can be of both extra- or intracellular origin. The rate and magnitude of the Ca2+ transient determines the rate and strength of heart contraction. The contraction-relaxation cycle is the cellular correlate of the heartbeat.</p
Astronomical and magnetic observations executed on the Congo Free State territory by A. Delporte and L. Gillis: F. Folie's report
No full textThe author establishes a report on A. Delporte and L. Gillis’ work on the astronomical and magnetic observations executed on the Congo Free State territory.L’auteur établit un rapport sur un travail de A. Delporte et L. Gillis sur les observations astronomiques et magnétiques exécutées sur le territoire de l'Etat Indépendant du Congo
Depression and Gender: The Expression and Experience of Melancholy in the Eighteenth Century
No full textThis thesis investigates the life and work of six eighteenth-century writers, two male and four female. It explores their experience of depression through their letters and other autobiographical material, and examines the ways in which they represent melancholy in their poetry and prose. The subject of Chapter Two is Thomas Gray, whose real life persona as the lonely intellectual is also identifiable in his poetry. The Scottish poet Robert Fergusson is studied in Chapter Three. Fergusson’s lively and vigorous mind was shattered in the months leading up to his death, during which time some of his writing became darkly nihilistic. Chapter Four looks at Anne Finch, Countess of Winchilsea, a lifelong depressive who often wrote about her feelings of despair in her poetry. Chapter Five explores Lady Mary Wortley Montagu. She was a courageous and controversial figure, but despite her resilience, on occasion in her letters she reveals her vulnerability and susceptibility to low spirits, a mood which is sometimes expressed in her creative writing. Sarah Scott, whose life and work have not yet been considered in relation to the subject of melancholy, is examined in Chapter Six. Her novel includes several low-spirited and depressed female characters who are continually seeking asylum from a hostile world. Chapter Seven analyses Charlotte Smith, a mother of twelve children whose unhappy marriage ended in separation. Smith wrote extensively about her depression in her letters, prefaces, poetry and novels.
This study shows that the women in particular use their writing on melancholy and depression to express their discontent with the confined way in which they are often expected to live out their lives
Integrated responses of the heart to acute changes in temperature
No full textAn acute change in physiological temperature can have a significant impact on heart function in fish, and as a result, the delivery of blood to the tissues. A decrease in temperature causes a reduction in the rate of pacemaker firing, an increase in action potential duration, and a decrease in the sensitivity of the myofilaments to Ca2+. Comparatively, an increase in physiological temperature can increase the rate of pacemaker firing, decrease the duration of action potential duration and increase the sensitivity of the myofilaments to Ca2+. These direct effects of temperature on cardiac function can be reduced as a result of adrenergic stimulation. However, too much of an increase in temperature can cause the heart to effectively stop working. As fish approach this temperature (upper lethal temperature) the counter movement of Na+ and K+ across the myocyte membrane becomes imbalanced, and this can lead to cardiac arrhythmias and the collapse of heart function.</p
- …
