46 research outputs found
Development and characterization of gelatin-based herbal hydrogels for managing infected wounds
No full text59-69The present study is aimed at evaluating the antioxidant and antimicrobial properties of aqueous extracts of the plants Moringa olifera (drumstick tree or murungai), Sesbania grandiflora (vegetable hummingbird or agati), Basella alba (malabar spinach or pasalai), and then developing herbal hydrogel with gelatin to improve its pharmacological properties and to use it as a primary dressing for managing infected wounds. The aqueous extracts of murungai, agati, pasalai and the herbal hydrogels has been tested in vitro against wound infecting microrganisms by well-diffusion method and micro-dilution method. Both plant extracts and herbal hydrogel are found to inhibit the growth of Gram positive, Gram negative and polymicrobial cultures. According to EN13726, all the three herbal hydrogels manage the simulated exudates effectively. Hence, the hydrogels developed in the present study could be used to manage infection and also moderately exudating wounds
K-core of co-author network (k = 10).
No full text<p>The size of the node denotes the number of papers and the thickness of interconnecting lines (edges) denotes the number of co-authored papers between the authors. Authors having 10 or more co-author links during the study period have been visualized.</p
Mesh materials and hernia repair
No full textHernia incidence has been observed since ancient time. Advancement in the medical textile industry came up with the variety of mesh materials to repair hernia, but none of them are without complications including recurrence of hernia. Therefore individuals once developed with the hernia could not lead a healthy and comfortable life. This drawn attention of surgeons, patients, researchers and industry to know the exact mechanism behind its development, complications and recurrence. Recent investigations highlighted the role of genetic factors and connective tissue disorders being the reason for the development of hernia apart from the abnormal pressure that is known to develop during other disease conditions. This review discusses different mesh materials, their advantages and disadvantages and their biological response after its implantation
Novel mutations in ATPase 8, ND1 and ND5 genes associated with peripheral neuropathy of diabetes
No full textType 2 Diabetes (T2D), being a complex, multi factorial metabolic disorder, its chronic complications development remains puzzled. In this case report, we describe four novel mutations in Cyt b, ATPase 8, ND1 and ND5 genes’ synergistic activity as plausible factors for the secondary complications of a patient with chronic T2D
Monsoonal Landscapes: Territorial adaptation through co-habitation in critical geographies
No full textEmergence of humans as the dominant species of the planet have come along with extreme manipulation of the earth’s systems to sustain this dominance. The Anthropocene has lasted a little over 200 years has perhaps seen the most shift from completely natural systems to requiring an additional man-made system to aid exponential growth of our species. Among earth’s systems, climate is one of the most complex factors determining energy balance of living organisms and determines energy gains and losses from organisms.India encompasses a wide range of complex territories with rich biodiversity living alongside some of the world’s highest population densities. Historically the Indians have lived and adapted to these resource abundant terrains through traditional ecological practices that aligned with the ecological systems and governed the socio-cultural practices. The current globalised world has been built upon with technological, infrastructural, sociological political and capitalistic growth has wretched devastating effects on the environment that supports us. India being a colonised country and exploited for its resources for centuries still holds traces of it in the infrastructural and production systems, in this case in the Periyar-Vaigai river basins. The region characterised by complex terrain, excessive manipulation of landforms and alteration of its resource cycles especially in water cycles by storing water in multiple dams experiences excess water flows during monsoons, causing flooding on its western slopes and proves to be the only hope for drought prone region on its eastern side. Governing such complexities lies with arbitrary administrative borders dividing the control between different states and various different departments controls the flow and management of resource which often falls short of preventing catastrophes or just management of resources.Extreme weather events in the recent past has exasperated the effects in these fragile habitats, thus the project aims to firstly mitigate the risks associated with failing monsoon, further restore the balance of the ecological system in the region. By building back resilience through co-habitation of social-ecological systems, aligned to nature using human knowledge the design aims to place value on nature rather than exploit it. The project envisions the transition from a local adaptation towards building up the system on the regional scale. It deals with primary production, anthropogenic control with respect to grey infrastructure, values and the role of ecosystems in maintain this balance. By synchronising these various systems the projects attempts at bringing back a dynamic equilibrium to this region, through methods like literature reviews, synthetic cartography and research by design.Architecture, Urbanism and Building Sciences | Transitional Territorie
Managing Leadership Development from a Gender Equity perspective: A case study approach in a typical materials company
No full textDiversity, Equity, and Inclusion are one of the latest topics getting attention among companies and universities. This reflects societal representation for gender ratios and many organizations have set goals on gender equality in creating a sustainable and innovative workplace. However, the statistics show that there is sluggish growth for women in managerial positions. This is creating a problem for promoting equity at leadership levels in every organization. Equity and equality are not the same as the former is closer to justice creating the same opportunities for all people with different abilities. Even though organizations can able to promote gender equality and achieve it with a better ratio, there is a struggle to increase women's representation at different leadership levels. The global scenario also shows that the representation of women on board and C-suite (Chief executive level like CEO, CFO, etc) is very low demanding gender equity at leadership levels. Thereby, a case study is performed in Celanese, a materials company that has better gender equality across the organization.This research is executed as an embedded single case study in both the global and Dutch context to understand this scenario and their gender representation at the management level. This is, in particular, to relate gender equality ratio progress and effectiveness for development programs to promote more women leaders supporting equitable workplace. The embedded case study is performed through ethnography research in terms of observations, qualitative interviews, and focused group discussions inside the organization. This approach helps to understand the existing scenario for women's representation and leadership development opportunities in a typical materials company. This is extended for industrial benchmarks at the global level as a comparison of gender equality ratios against their competitors. The leadership interviews with both genders focusing on women leaders are done and the outputs showed the driving factors, challenges, and future requirements to create equity-focused leadership. Further analysis is done to extract the key elements impacting gender equity for leadership development programs.Whereas, focused group discussions are aimed at involving employees at different levels and employees who are closely involved in leadership programs. So, focused group discussion is done with the Young professional group that comprises employees at different levels and Human Resources team who drives leadership programs. These discussions acted as data triangulation for qualitative interviews and provided more insights into leadership development programs from different perspectives. As a result, the existing gaps and challenges for the leadership development of women employees in an organization are studied. Facts derived from the organizational level and qualitative results provided enough reasons for ineffective development programs in supporting equity at leadership levels. This is evident that leadership levels demanded more women employees and necessary driving factors to motivate them. This also emphasized how HR policies and role model representation can contribute better in driving more female employees into leadership levels.However, the missing factor is equitable actions in leadership development programs to create an inclusive environment. Thereby, a leadership development cycle is developed to strengthen various processes making the leadership program as equity-focused and motivating female employees for leadership positions. However, the recommendations are derived using the embedded single case study and explained briefly about a roadmap showing the next future phases for equity at leadership levels and their decision-making impact on innovation. Finally, a leadership development framework is developed showing the possible methods and processes for driving more female employees from the organizational level to the leadership level. This leadership framework shows how women leaders need effective equity-focused development programs using equitable actions considering both social and professional barriers. Using this framework, the practical implications are summarized for promoting women leaders at leadership levels through equity-focused leadership development programs.Management of Technology (MoT
