68 research outputs found
Multiple recurrences in Pityriasis rosea - A case report with review of the literature
No full textPityriasis rosea (PR) is a common benign cutaneous disorder of children and young adults. The etiology of this condition is still unknown. Despite the common occurrence, second episode of PR is noted only in 1-3% of the cases. Multiple recurrences (three or more episodes) are extremely uncommon and to the best of our knowledge, only few patients have been reported in the literature. Due to the benign nature of the disease, these recurrences may be either underestimated or unreported. Till date, there are no predisposing factors identified for the occurrence of these multiple episodes. We report a case of pityriasis rosea in an 11-years-old male with three episodes with review of the literature
Update on the Management of Vitamins and Minerals in Cystic Fibrosis
No full textAdvancements in respiratory and nutrition management have significantly improved the survival of patients with cystic fibrosis (CF). With the availability of several nutrition interventions such as oral/enteral nutrition supplements, enteric-coated pancreatic enzymes, and water-miscible CF-specific vitamin supplements, frank vitamin deficiencies—with the exception of vitamin D—are rarely encountered in current clinical practice. Whereas they were previously considered as micronutrients, our current understanding of fat-soluble vitamins and minerals as antioxidants, immunomodulators, and disease biomarkers has been evolving. The impact of highly effective modulators on the micronutrient status of patients with CF remains elusive. This narrative review focuses on the updates on the management of fat-soluble vitamins and other micronutrients in CF in the current era and identifies the gaps in our knowledge
Entomopathogenic Fungi for the Management of Calopepla leayana on Gmelina arborea
No full textEntomopathogenic fungi, Beauveria bassiana and Metarhizium anisopliae were isolated and identified as natural pathogens of Calopepla leayana. Both the species of fungi were effective against the larval and adult stages of C. leayana causing white and green muscardine diseases respectively. It was also found that B. bassiana was more pathogenic to the pest as compared to M. anisopliae. The susceptibility of larvae and adults was negatively associated with the age and positively associated with the fungal spore concentration. In all the stages from I instar to adult, the highest mortality was observed in 10% of 1x109 spores/ml concentration of B. bassiana among 1, 2.5, 5 & 10% of 1x109 spores/ml concentration. It was also reflected in probit analysis that the concentration of spores required to kill fifty percent of the population was ranges from 0.09% to 5.98% of 1x109 spores/ml concentration of B. bassiana and 1.02% to 9.72% of 1x109 spores/ml concentration of M. anisopliae. The larvae of I instar have shown highest mortality, which gradually decreased with the increase in age or decrease in the concentration of fungal spores. Mass production of B. bassiana using different substrates was attempted to harvest ample amount of spores. This study revealed that spore production was directly proportional to the mycelial weight and incubation period. From the seven substrates tested, wheat flour was identified as one of the suitable substrates for the mass production of B. bassiana. A field trial was conducted to test their efficacy under field conditions. 72-93% mortality was observed in field conditions.-----------------------------------------------------------------------------------------------------Division of Bioprospecting, Institute of Forest Genetics and Tree Breeding, Coimbatore-641002, Tamilnadu, India*Corresponding author, Email: [email protected] This Article As: N. Senthilkumar and S. Murugesan. 2010. Entomopathogenic Fungi for the Management of Calopepla leayana on Gmelina arborea. J. Ecobiotechnol. 2(3): 01-0
Utility of fecal elastase-1 in estimating pancreatic function in cystic fibrosis – A scoping review
No full textScoping Revie
Utility of fecal elastase-1 in estimating pancreatic function in cystic fibrosis – A scoping review
No full textScoping Review
Background and Rationale
In people with cystic fibrosis (pwCF), approximately 85% have exocrine pancreatic insufficiency (EPI). The gold standard test for evaluating EPI is direct pancreatic function testing using endoscopic pancreatic stimulation test. Even though it is the standard test, it is obsolete in clinical practice due to its invasiveness. The commonly used indirect tests include coefficient of fat absorption (CFA) and quantitative fecal elastase-1 (FE-1) estimation (1). CFA is nonspecific for pancreatic function as the results could be affected in other causes of malabsorption or maldigestion. Further, it is cumbersome as the stool collection involves for 72 hours and dietary intake of fat also should be tightly controlled. FE-1 is commonly used noninvasive test commonly utilized to estimate the pancreatic status (function) in pwCF. The cut-off values utilized widely ranges between 100-200 ug/gm of stool with lower cut off provide higher specificity for EPI. However, there is limited literature regarding its diagnostic accuracy in CF and multiple challenges in addressing several questions such as when to estimate the pancreatic function, what cut-off value to use and the diagnostic accuracy of the test.
Here in, we intend to explore the diagnostic accuracy of FE-1 using a scoping review methodology, and also will compare the utility of FE-1 with other methods of EPI such as the coefficient of fat absorption (CFA), endoscopic pancreatic stimulation test, stool chymotrypsin, etc. Due to the variabilities in the cut off, wide range of patient population (neonates, infants, children and adults), and also the availability of different diagnostic methods to compare, we intend to carry out a scoping review. Again, given these limitations, a formal quality assessment will not be done here (unlike in systematic review) (2-3)
Utility of fecal elastase-1 in estimating pancreatic function in cystic fibrosis – A scoping review
No full textScoping Revie
Crystal growth, piezoelectric, non-linear optical and mechanical properties of lithium hydrogen oxalate monohydrate single crystal
No full textThe prevalence of platelet activating factor acetylhydrolase single nucleotide polymorphisms in relationship to necrotizing enterocolitis in Northwest Louisiana infants
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