19 research outputs found
Semiquinone Radical Intermediate in Catecholic Estrogen-Mediated Cytotoxicity and Mutagenesis: Chemoprevention Strategies with Antioxidants
No full textEffects of Hypoxia on Radiation-Responsive Stress-Activated Protein Kinase, p53, and Caspase 3 Signals in TK6 Human Lymphoblastoid Cells.
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Damage to liposomal lipids: protection by antioxidants and cholesterol-mediated dehydration
No full textThe Role of Hydration in Stabilization of Liposomes: Resistance to Oxidative Damage of PEG-Grafted Liposomes
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Usu venisse hoc : unity and purpose of rhetoric in the Bellum Africum
Full text linkThis report seeks to bring better understanding specifically to the rhetoric of the Bellum Africum and how that understanding sheds new light on the political atmosphere in the aftermath of the assassination of Julius Caesar. Through a literary analysis of various vignettes, monologues, and examples of adaptations of Caesar’s own rhetorical style within the Bellum Africum, I look to prove that the work’s anonymous author consciously sought to create a unified rhetorical program throughout his text which aids the image of the Caesarian cause as it stands at his time of writing in 44/3 BCE. I have found that he does this through a multi-part strategy: he took advantage of the circumstances of the African War, especially Scipio’s alliance with Juba, to reframe the civil war as defense from foreign aggression and to downplay Caesar’s own monarchical tendencies before his death; pulling from his own military background, he focused in especially on matters of military and political procedure to most vividly contrast the ‘Romanness’ of the values of the Caesarians and the opposing Pompeians; he divided the legacy of the original Optimates from that of the contemporary Pompeians, casting them as a disconnected and inferior set of political leaders; lastly, he amplified the pragmatic nature of Caesar’s clementia, dramatized Caesar’s emotional loyalty to the state and its people, and introduced religious connection to Caesar’s idea of felicitas to elevate Caesar and shift Caesar’s original model as servant to the Republic to appear more like a singular leader or savior of the Republic.Classic
Molecular and cellular assessment of Ginkgo biloba extract as a possible ophthalmic drug
No full textWe have investigated the biochemical and cell biological basis of the reported beneficiary effects of the leaf extracts of the plant Ginkgo biloba, which has been used as a possible ophthalmic drug. The antioxidant, antimicrobial, anti-apoptotic and cytoprotective properties of the standardized extract called EGb761 were assayed. Chemical stresses were induced in cells using alloxan or dexamethasone, and the effect of EGb761 on them was studied using the MTT and TUNEL assays. Its ability to modulate the activities of some antioxidant enzymes was tested in vitro. In addition, cataract was induced in rats through selenite injection, and the effect of EGb761 administration on the progression of cataract was studied using slit lamp examination. Ginkgo biloba was found to be an excellent antioxidant. It readily scavenges reactive oxygen and nitrogen radicals and inhibits oxidative modifications that occur to proteins in vitro. It enters intact cells and protects them from alloxan-mediated and light-mediated stress, and the nuclear DNA from single strand breaks. It also effectively inhibits chemically induced apoptosis. It does not modulate the activities of endogenous antioxidant enzymes, nor does it have any significant antimicrobial activity. Unlike some other plant extracts, it is not phototoxic. In experiments wherein selenite cataract was induced in laboratory rats, treatment with the extract significantly retards the progression of lens opacification in vivo. Ginkgo biloba's inherent antioxidant, antiapoptotic and cytoprotective action and potential anticataract ability appear to be some of the factors responsible for its beneficial effects
γ-Irradiation Damage to Liposomes Differing in Composition and Their Protection by Nitroxides
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