250,948 research outputs found
Interview with Samuel C. McCulloch
No full textProfessor Emeritus of HistoryFounding Dean of History, 1963Chair of UCI Academic Senate, 1978-1980UCI Historian, 1988Digitized 2013 by Avant Productions, Inc
On the Hodge conjecture for products of certain surfaces
No full textIn this thesis we prove the Hodge conjecture for products of smooth projective surfaces S(_1) x S(_2), where S(_2) = A is an Abelian surface and S (_1) is such that P(_g)(S(_1)) = 1, q = 2. We hereby provide new examples in dimension 4 where the Hodge conjecture holds
Acute Ethanol Administration Rapidly Increases Phosphorylation of Conventional Protein Kinase C in Specific Mammalian Brain Regions in Vivo
No full textBackground
Protein kinase C (PKC) is a family of isoenzymes that regulate a variety of functions in the central nervous system including neurotransmitter release, ion channel activity, and cell differentiation. Growing evidence suggests that specific isoforms of PKC influence a variety of behavioral, biochemical, and physiological effects of ethanol in mammals. The purpose of this study was to determine whether acute ethanol exposure alters phosphorylation of conventional PKC isoforms at a threonine 674 (p-cPKC) site in the hydrophobic domain of the kinase, which is required for its catalytic activity.
Methods
Male rats were administered a dose range of ethanol (0, 0.5, 1, or 2 g/kg, intragastric) and brain tissue was removed 10 minutes later for evaluation of changes in p-cPKC expression using immunohistochemistry and Western blot methods.
Results
Immunohistochemical data show that the highest dose of ethanol (2 g/kg) rapidly increases p-cPKC immunoreactivity specifically in the nucleus accumbens (core and shell), lateral septum, and hippocampus (CA3 and dentate gyrus). Western blot analysis further showed that ethanol (2 g/kg) increased p-cPKC expression in the P2 membrane fraction of tissue from the nucleus accumbens and hippocampus. Although p-cPKC was expressed in numerous other brain regions, including the caudate nucleus, amygdala, and cortex, no changes were observed in response to acute ethanol. Total PKC? immunoreactivity was surveyed throughout the brain and showed no change following acute ethanol injection
"The Duel" by Samuel C. Edger, 31 March 1832
No full textAn essay, possibly by Samuel C. Edger (or Samuel C. Edgar), relaying the story of a pistol duel in London between "Wilson" and "Trevor." Possibly a school assignment at the American Literary, Scientific and Military Academy (in Norwich, Vermont) or Jefferson College (in Washington, Mississippi), although association with either school is uncertain; dated 31 March 1832.Transcription by Raymond Bouchard. Transcriptions may be subject to error
Samuel Bancroft, Jr., c. 1910
No full text1 photographic printPhotograph of Samuel Bancroft, Jr., c. 1910
Reverend Samuel C. Alexander
No full textPhotograph of Rev. Samuel C. Alexander. Labeled ""Le Rue Lemer 206 Market St. Harrisburg PA"" on front, handwritten note on back reads ""Rev. Samuel C. Alexander S. D. Please return to Miss S. C. Alexander Millerstown Pennsylvania"
Mrs. Samuel C. Alexander
No full textPhotograph of Mrs. Samuel C. Alexander, printed note reads ""Lenneys Studio Market St. Newport PA"", typed label reads ""Mrs. Samuel C. Alexander Wife of the Co-founder: Rev. S. C. Alexander"
Professor Samuel K. Talmadge to James C. Furman
No full textA two page letter and envelope from Professor Samuel K. Talmadge to James C. Furma
[Amnesty Letter] ID246 / Waugh, Samuel C.
No full textThis letter was written by Samuel C. Waugh to President Andrew Johnson in response to the President's Amnesty Proclamation of 29 May 1865. The writer indicates his county of residence as Ashe Co., NC and states his occupation as Farmer
Reverend Samuel C. Alexander
No full textPhotograph of Rev. Samuel C. Alexander, handwritten note on back reads ""S. C. Alexander"
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