35 research outputs found
Active surveillance for prostate cancer: an update
No full textThis is the author accepted manuscript. The final version is available from Wiley via the DOI in this record. An increasing number of men diagnosed with localised prostate cancer has been accompanied by more men being considered for active surveillance as a management option. Here the author provides an update on recent developments in active surveillance and changes to NICE guidance
Knowledge and attitudes of General Practitioners and sexual health care professionals regarding human papillomavirus vaccination for young men who have sex with men
No full textMen who have sex with men (MSM) may be at higher risk for human papillomavirus (HPV)-associated cancers. Healthcare professionals’ recommendations can affect HPV vaccination uptake. Since 2016, MSM up to 45 years have been offered HPV vaccination at genitourinary medicine (GUM) clinics in a pilot programme, and primary care was recommended as a setting for opportunistic vaccination. Vaccination prior to potential exposure to the virus (i.e. sexual debut) is likely to be most efficacious, therefore a focus on young MSM (YMSM) is important. This study aimed to explore and compare the knowledge and attitudes of UK General Practitioners (GPs) and sexual healthcare professionals (SHCPs) regarding HPV vaccination for YMSM (age 16–24). A
cross-sectional study using an online questionnaire examined 38 GPs and 49 SHCPs, including 59 (67.82%) females with a mean age of 40.71 years. Twenty-two participants (20 SHCPs, p < 0.001) had vaccinated a YMSM patient against HPV. GPs lack of time (25/38, 65.79%) and SHCP staff availability (27/49, 55.10%) were the main reported factors preventing YMSM HPV vaccination. GPs were less likely than SHCPs to believe there was sufficient evidence for vaccinating YMSM (OR = 0.02, 95% CI = 0.01, 0.47); less likely to have skills to identify YMSM who may benefit from vaccination (OR = 0.03, 95% CI = 0.01, 0.15); and less confident recommending YMSM vaccination (OR = 0.01,
95% CI = 0.00, 0.01). GPs appear to have different knowledge, attitudes, and skills regarding YMSM HPV vaccination when compared to SHCPs
Recruiting Marginalised groups to a Randomised Control Trial: TRANSFORM(ing) methods and approaches for the prostate Screening Trial
No full textA large trial, the TRANSFORM trial, has been launched to find the best way to screen men for prostate cancer (blood test, genetic testing or MRI scan) https://prostatecanceruk.org/research/transform-trial [prostatecanceruk.org]. We will provide information on our approach to recruiting marginalised groups (ethnic minority groups and people with a learning disability for example) to a Randomised Control Trial and how co-production and co-researchers have supported the development of our approach to date. The initial focus will be to evaluate patient participation in (uptake of) the screening programmes for prostate cancer following different types of invitation methods before moving to full trial
INVESTIGATION OF THE RELATIONSHIP BETWEEN SOCIOEMOTIONAL DEVELOPMENT AND INTELLECTUAL DEVELOPMENT OF DEVELOPMENTALLY DISABLED AND NORMAL BLACK CHILDREN
No full textSource: Dissertation Abstracts International, Volume: 39-01, Section: A, page: 2200.Ph.D. American University 1977.Englis
Prostate cancer treatment choices: the GP’s role in shared decision-making
No full textThis is the author accepted manuscript. The final version is available from the Royal College of General Practitioners via the DOI in this recor
Lymphoma for GPs across the cancer continuum
No full textThis is the author accepted manuscript. The final version is available from SAGE Publications via the DOI in this recordLymphomas are a diverse and relatively common cancer type in the UK. Early diagnosis of
lymphoma is vital for improving patient outcomes. The majority of patients diagnosed with
lymphoma have a life expectancy of at least five years. Lymphoma treatments can have
long-term health consequences, and patients with a history of lymphoma have a higher risk
of subsequently developing other cancers. More robust evidence for the early diagnosis of
lymphoma in primary care has been published in recent years, and the classification of
lymphoma has recently been updated by the World Health Organization (WHO). This article
is focused on the diagnosis of lymphoma in adolescents and adults, and the on-going care
needs for all patients who are being treated for lymphoma or have survived a diagnosis of
lymphoma. Further information about lymphoma and other cancers in children can be
found in the InnovAiT article by Dr Jennifer Kelly from 2017
Active surveillance for prostate cancer: an update
No full textAn increasing number of men diagnosed with localised prostate cancer has been accompanied by more men being considered for active surveillance as a management option. Here the author provides an update on recent developments in active surveillance and changes to NICE guidance
Fertility among blacks in the southern black belt 1950 to 1970, 1977
No full textFertility of the ninety-size counties of the Southern black belt was examined in light of the demographic and socio-economic factors of the area. Measures of fertility, family income, population change, and female labor force participation were made to test two hypotheses. These hypotheses were based on the theoretical framework from the review of literature. Data were collected from the United States Census and Vital Statistics for 1950 and 1970. Fertility was found to be high in the black belt in both years with a decrease seen in 1970. The unique structure of the black belt, demographically and socio-economically, was found to influence the measure of fertility. However, both the history and the forementioned factors were found to be important in studying the fertility of the black belt
Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients
No full textBackground. The association between hypoalbuminaemia and a new diagnosis of cancer is as yet unknown.Objective. This study aimed to assess whether unexplained hypoalbuminaemia was associated with an increased risk of subsequent new cancer diagnosis within the next 12 months.Methods. A cohort study was performed using a large UK database of adult primary care patients. Patients with a serum albumin test, either low or normal, were followed for 12 months for a new diagnosis of non-skin cancer. Logistic regression was used to assess for relationships between hypoalbuminaemia and cancer diagnoses.Results. A total of 100 122 participants had at least one albumin test result. Of these, 5753 (5.75%) had a result <35g/l, of whom 1634 developed cancer within 12 months. Of the 94 116 patients with normal albumin values, 13 906 developed cancer. Hypoalbuminaemia was associated with an increased risk of subsequent cancer diagnosis within 12 months (odds ratio [OR]: 2.29; 95% confidence interval [CI]: 2.15–2.43). This association was smaller in magnitude after controlling for other conditions known to affect albumin levels (OR: 1.29; 95% CI: 1.12–1.49).Conclusions. Low albumin levels were associated with an increased risk of cancer. This finding needs to be confirmed in other primary care populations
Telehealth interventions for primary prevention of cardiovascular disease: A systematic review and meta-analysis
No full textObjectiveTo assess the effectiveness of telehealth interventions in the primary prevention of cardiovascular disease in adult patients in community settings.MethodsSystematic literature review of randomised controlled trials comparing the effectiveness of telehealth interventions to reduce overall cardiovascular disease (CVD) risk and/or to reduce multiple CVD risk factors compared with a non-telehealth control group was conducted in June 2013. Study quality was assessed using the Cochrane Risk of Bias tool. Fixed and random effects models were combined with a narrative synthesis for meta-analysis of included studies.ResultsThree of 13 included studies measured Framingham 10-year CVD risk scores, and meta-analysis showed no clear evidence of reduction in overall risk (SMD − 0.37%, 95% CI − 2.08, 1.33). There was weak evidence for a reduction in systolic blood pressure (SMD − 1.22 mm Hg 95% CI − 2.80, 0.35) and total cholesterol (SMD − 0.07 mmol/L 95% CI − 0.19, 0.06). There was no change in High-Density Lipoprotein cholesterol or smoking rates.ConclusionThere is insufficient evidence to determine the effectiveness of telehealth interventions in reducing overall CVD risk. More studies are needed that consistently measure overall CVD risk, directly compare different telehealth interventions, and determine cost effectiveness of telehealth interventions for prevention of CVD
