86,731 research outputs found
Development of membrane sensitivity to the parthenogenetic agent calcium ionophore A23187 during meiotic maturation in the hamster oocyte
No full textThe response to the parthenogenetic agent Ca-ionophore A23187 was studied in hamster oocytes undergoing meiotic maturation, by using electrophysiological techniques. Following germinal vesicle breakdown, the activating agent induces a long-lasting hyperpolarization accompanied by an increased membrane conductance. The duration of the response progressively shortens during the long metaphase I stage. Terminal metaphase I oocytes respond to A23187 by a hyperpolarization that is very similar to that seen in metaphase II oocytes. The ionic mechanism of the change in the membrane sensitivity to A23187 during meiotic maturation is discussed
Testing for heterogeneity of preferences in randomized experiments: a satisfaction-based approach applied to multiplayer prisoners’ dilemmas
No full textWe use experimental data from the ‘vote with the wallet’ multiplayer prisoner’s dilemma to investigate with a finite mixture approach the effect of a responsible purchase on players’ satisfaction. We find clear-cut evidence of heterogeneity of preferences with two groups of players that differ significantly in terms of effects of the responsible choice on satisfactio
A new conceptual modeling framework for a distributed object-based industrial simulation system (DOBIS).
No full textDifferent simulation applications require different levels of model detail. As the complexities and flexibilities of manufacturing systems are ever increasing, the flexibility of simulation system to model real world systems with arbitrary levels of detail becomes important. Existing simulation systems provide predefined models that limit their flexibility. In this thesis, the author develops a conceptual modeling strategy that combines the Event-Scheduling strategy and the Object-Oriented paradigm. A basic element is developed to model any resource and is mapped to an extended Parallel DEVS formalism. This strategy provides general framework and system requirements for further computerized development. Such a system is able to implement recursive hierarchical modeling, which provides the environment to model real world systems at any level of detail. The basic element also provides simplified functions and syntaxes that make the system easy to learn and maintain. A two-layer object construction framework is also discussed to pushing down "low-level" aspects of simulation to the systems level, and away from the user. Several examples are developed in this thesis, which illustrate DOBIS has the potential to outperform existing systems in several aspects.Dept. of Industrial and Manufacturing Systems Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis2001 .G355. Source: Masters Abstracts International, Volume: 41-04, page: 1168. Adviser: F. Salustri. Thesis (M.A.Sc.)--University of Windsor (Canada), 2002
The impact of health expenditure on the number of chronic diseases
No full textWe investigate the impact of health expenditure on health outcomes on a large sample of Europeans aged above 50 using individual and regional level data. We find a negative and significant effect of lagged health expenditure on subsequent changes in the number of chronic diseases. This effect varies according to age, health behavior, gender, income, and education. Our empirical findings are confirmed also when health expenditure is instrumented with parliament political composition
The relationship between corruption and chronic diseases: evidence from Europeans aged 50 years and older
No full textObjectives: Do people living in more corrupted countries report worse health? We answer this question by investigating the relationship between country-level corruption and the number of chronic diseases for a sample of Europeans aged above 50. Methods: We link a rich panel dataset on individual health and socio-demographic characteristics with two country-level corruption indices, analyse the overall relationship with pooled ordinary least squares and fixed-effect models, explore heterogeneous effects driven by country and individual factors, and disentangle the effect across different public sectors. Results: Individuals living in more corrupted countries suffer from a higher number of chronic diseases. The heterogeneity analysis shows that (1) health outcomes are worsened especially for respondents living in relatively low-income countries; (2) the health of females and people with poor socio-economic status is more affected by corruption; (3) the corruption–health negative link mainly occurs for cardiovascular diseases and ulcers; (4) only corrupted sectors linked with healthcare are associated with poorer health. Conclusions: We inform the policy debate with novel results in establishing a nexus between corruption and morbidity indicators
Deborah Meier (1931-)
No full textil saggio affronta l'esperienza pedagogica di Deborah Meier. Pedagogista americana è stata direttrice della rete di scuole primarie di Central Park East a New York e parte della Coalition of Essential Schools. Ancora in attività, è un punto di riferimento a livello nazionale del dibattito pubblico americano sull'educazione primaria
The vote with the wallet game: Responsible consumerism as a multiplayer prisoner's dilemma
No full textSocially responsible consumers and investors are increasingly using their consumption and saving choices as a 'vote with the wallet' to award companies that are at vanguard in reconciling the creation of economic value with social and environmental sustainability. In our paper, we model the vote with the wallet as a multiplayer prisoner's dilemma, outline equilibria and possible solutions to the related coordination failure problem in evolutionary games, apply our analysis to domains in which the vote with the wallet is empirically more relevant, and provide policy suggestions
A war is forever: The long-run effects of early exposure to World War II on trust
No full textThis paper examines the long-term effect of conflict on trust by using changes in places and timing of combats during World War II. We focus on the pre-school period, an important life stage for the formation of trust and an age where war exposure may persist throughout life. We find robust evidence that individuals exposed to combats in the first six years of life display lower trust and social engagement well into adulthood. In light of the well-known relationship between trust and collective action, our results lend credence to the theory that violent conflict inhibits well-functioning government in long run
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