9,344 research outputs found
sj-docx-1-bbi-10.1177_11779322211055892 – Supplemental material for Prognostic Value Estimation of BRIP1 in Breast Cancer by Exploiting Transcriptomics Data Through Bioinformatics Approaches
No full textSupplemental material, sj-docx-1-bbi-10.1177_11779322211055892 for Prognostic Value Estimation of BRIP1 in Breast Cancer by Exploiting Transcriptomics Data Through Bioinformatics Approaches by Umama Khan and Md. Salauddin Khan in Bioinformatics and Biology Insights</p
Chapter 14: MD Anderson Publications and Publication Ethics
No full textDr. Goepfert has served on a number of editorial boards and is keenly interested in the educational dissemination of information critical to cancer research. In this section he talks about some of MD Anderson’s publications and also addresses some controversies with publication. He first raises the ethical issue of how authorship is assigned to a manuscript going out for publication. Today there are guidelines for assigning authorship, but twenty years ago, he explains, some department chairs at MD Anderson reviewed all manuscripts going for publication and insisted on being listed as first author of an article, whether they made any contribution to the research or not. Dr. Goepfert contrasts his own practice of putting his name on a paper only if he has contributed. Dr. Goepfert then shifts subjects and describes several MD Anderson educational publications, beginning with Cancer Bulletin, distributed free to all physicians across Texas.https://openworks.mdanderson.org/mchv_interviewchapters/2010/thumbnail.jp
sj-pptx-1-evb-10.1177_11769343231182258 – Supplemental material for Beta, Delta, and Omicron, Deadliest Among SARS-CoV-2 Variants: A Computational Repurposing Approach
No full textSupplemental material, sj-pptx-1-evb-10.1177_11769343231182258 for Beta, Delta, and Omicron, Deadliest Among SARS-CoV-2 Variants: A Computational Repurposing Approach by Mohammad Mamun Alam, Sumaiya Binte Hannan, Tanvir Ahmed Saikat, Md Belayet Hasan Limon, Md Raihan Topu, Md Jowel Rana, Asma Salauddin, Sagar Bosu and Mohammed Ziaur Rahman in Evolutionary Bioinformatics</p
A SPATIAL ANALYSIS ON THE PROVISION OF URBAN PUBLIC SERVICES AND THEIR DEFICIENCIES: A STUDY OF SOME SELECTED BLOCKS IN KHULNA CITY, BANGLADESH
No full textIn most of the cities in Bangladesh, there is a considerable lacking in providing public services comparing with the demand. This study aims to identify the deficiencies in providing public services in three selected blocks of Khulna city, Bangladesh. Blocks are considered here as an individual small administrative unit within the jurisdiction of Khulna City Corporation. First the study identified the spatial concentration of the services among the blocks. The comparative situation of the blocks in terms of public services was viewed by location quotient method and Gini coefficient and neighbourhood standard were consider to identify the deficiencies. The study found that two of the blocks are comparatively developed while the other one lag far behind the mean level of development of the city. Lastly on the basis of population and space standard, required facilities for each of the blocks were calculated.Urban Services, Defficiencies, Spatial Analysis, Khulna City.
Promise - Spring 2020
No full textRogers Award honors MD Anderson nursing assistant MD Anderson awards highest nursing honor Low-grade serous ovarian cancer survivor establishes research nonprofit Celebrity Chef Cooking Demo makes young cancer patients sous-chefs for a day Bob’s Encore: hope in the fight against pancreatic cancer Board of Visitors welcomes seven new members Board of Visitors awards highest distinction to longtime member A Conversation with a Living Legend raises 2 million for cancer research, education and prevention Get to know Advance Team’s Laura Nelson Cookbook author leaves her mark on gastric cancer researchhttps://openworks.mdanderson.org/promise/1001/thumbnail.jp
Chapter 09: Creating a New Way of Conducting Research and Caring for Patients in a Changing Environment
No full textIn this chapter, Dr. Dmitrovsky provides an overview of how MD Anderson must operate in the new environment of research and healthcare economics. He begins by explaining that scientific endeavors traditionally rely on decisive discoveries by individual investigators that also reveal opportunities to development treatments. Today, he says, this process moves ahead via team- and interdisciplinary science, and the institution must educate the next generations of researchers in this way of conducting research. At the same time, MD Anderson must operate in a context of a flat NIH budget while responding to the new economics of the Affordable Care Act. Next, he notes that MD Anderson is supporting the education of the next generation by making investments in junior faculty with the R. Lee Clark Fellowship Program. He explains the award (juried by experts outside of MD Anderson). Next Dr. Dmitrovsky notes that reductions are being made to the length and complexity of informed consent forms so faculty can spend less time on paperwork and more time for their primary activities. He then speaks briefly about faculty recruitment and retention efforts. Then Dr. Dmitrovsky talks about strategies used to encourage interdisciplinary investigation. He speaks in detail about finding ways to provide team members with proper recognition for their contributions (when contribution is traditionally measured by first or last author status) and linking credit to faculty promotion. He also talks about empowering team members to initiate investigations and provides some examples.https://openworks.mdanderson.org/mchv_interviewchapters/1641/thumbnail.jp
Chapter 09: Strengthening Biomedical Editing Nationwide and Within MD Anderson
No full textIn this Chapter, first briefly notes his involvement with the Southwest Chapter of the American Medical Writer’s Association and the Council of Biology Editors (with a 22-year membership). He then explains that he had his biggest impact while he served on the Board of Editors in the Life Sciences and in the late 80s worked on the Editorial Certification Examination Development Committee. He describes the examination he helped create to certify competence for editors of biomedical articles and explains the significance of certification. He notes that the Department of Scientific Publications at MD Anderson uses its own battery of tests to evaluate editors’ abilities for abstract reasoning, grammar, and other skills and talents.
Next, Mr. Pagel talks about his Department’s blog, “The Write Stuff,” and two significant projects: his role on the Historical Resources Center Steering Committee, and the development of panel discussions for the Department of Scientific Publications. To begin the discussion of the Steering Committee, he notes that Scientific Publications wrote The First Twenty Years, the first history of MD Anderson. Because of this association with the institution’s history, Mr. Pagel was asked to be part of the Steering Committee when the Historical Resources Center was formed and set as its first goal the publication of an updated institutional history. Mr. Pagel wanted the perspective to be broader than the first book, situating MD Anderson and cancer research in a larger context of other cancer institutions and the history of cancer research. Though not alone in holding this view, he says he had something to do with articulating it for the benefit of the Steering Committee. He describes how James Olsen was selected to be the author and notes other Steering Committee activities.https://openworks.mdanderson.org/mchv_interviewchapters/2275/thumbnail.jp
E. Harold Shryock, MD
No full textA teacher of the ages, administrator, author, lecturer, ambidextrous artist, trick cyclist, Chair of the Department of Anatomy, and Dean of the School of Medicine of Loma Linda University.All descriptions are taken verbatim from: Portraits of Honored Faculty by S. Wesley Kime, MD. Editor Raymond Herber, MD. (Loma Linda, Calif.: Alumni Association of School of Medicine of Loma Linda University, 2005) and are thus not up-to-date as to positions held or contributions made to Loma Linda University Health
Chapter 09: Reflections on Dr. Clifton Mountain and Data Collection Roles at MD Anderson
No full textMrs. Hermes begins this chapter with memories of how much she enjoyed working for Dr. Mountain over the course of 25 years. He taught her how to think about data, she explains, and she was listed as an author on a number of publications on lung cancer [see examples below]. She explains that Dr. Mountain left MD Anderson in 1993, but she continued to work freelance for him. She recalls that he set up the first conference on mathematics at MD Anderson, early in his career sometime in the sixties.
Next she comments on how the unique openness of Houston culture fit well with the bold visions that both R. Lee Clark and Eleanor MacDonald held for oncology. She says that her most important work was on Dr. Mountain’s staging system for lung cancer and she explains why staging the disease presented challenges.
She confirms that she was always interested in the implications of basic research for clinical findings. She credits Eleanor MacDonald for helping her to develop her curiosity and questioning style.https://openworks.mdanderson.org/mchv_interviewchapters/2036/thumbnail.jp
Physical model tests on new armour block Crablock for breakwaters to come to preliminary design guidance
No full textIn the design of rubble mound breakwaters, nowadays single layer systems using concrete armour units have become more common practice compared to conventional two layer systems. However, after the introduction of the accropode in eighties, a small number of single layer armour units have been developed over the years; for example core-loc, A-jack, xbloc, accropode-II, cubipod and core-loc II. Recently, a new concrete armour unit called crablock has been invented and applied as one layer system in one damaged breakwater at Al Fujeirah, UAE. In contrast to other existing monolayer units, the shape of this unit is symmetrical which allows placing both in uniform and random pattern. As the crablock unit is still under development, no design guidance exists yet for this concrete armour unit. To use crablock as monolayer system the preliminary design guidance on placement of crablock, stability and wave overtopping are required. This led the present research to investigate the placement pattern, packing density and wave overtopping over slope to come with first design guidance for the application of crablock. It should be mentioned that stability of the crablock against wave attack was also looked at, but that will be reported by Mr. André Broere, an MSc-student at Delft University of Technology. The present research was based on a literature study, small scale dry placement tests and small scale hydraulic tests in a wave flume. Regarding to the review of literature studies on the existing single layer units and crablock, set up of dry placement tests and flume tests have been made for this experimental research. Dry placement tests as well as 2D wave flume tests were carried out at the Fluid Mechanics Laboratory of the Faculty of Civil Engineering and Geosciences at Delft University of Technology, Netherlands. Both placement and hydraulic tests were executed with the use of small units. In total 14 independent placement test series were executed to investigate the placement pattern, placing grid and packing density of crablock. All the tests were performed on a 1:4/3 slope with the use of random and uniform placement in a rectangular as well as in a diamond shaped placing grid. Results of placement tests showed that uniform placement of crablock is achievable with the use of relatively small and smooth under layer in a rectangular placing grid. The performance of regular placement using a conventional under layer with size 1/10th to 1/15th of the size of the armour layer was not so satisfactory. Furthermore, it was found that uniform pattern was hardly reachable in a diamond-shaped grid with conventional under layer. However, irregular placement of crablock was certainly easier to construct and possible to place with higher accuracy compared to uniform placement in a diamond grid. It should be noted that all the tests using a conventional underlayer were performed without the fixation of first row due to the difficulties in placement with model crablock units. If this can be fixated by designing dedicated toe units (both in rotation and location) it may perform better. Still, the large underlayer makes it difficult to place uniformly. Finally, two preferred placing patterns appeared from the placement tests, a regular pattern in a rectangular grid using a relatively small under layer and a random pattern in a diamond grid using a conventional under layer. For the determination of wave overtopping, altogether 14 different test series were performed in a wave flume. In this research, two constant spectral wave steepnesses of 0.02 and 0.04 were tested together with two different orientations of units, two different placing grids and four different packing densities. The preferred placing patterns were constructed in a wave flume on a modelled breakwater cross-section in front of the sloping foreshore of 1:30. Each test series was comprised of number of sub tests for specific wave height and period. In each test series, wave heights and periods were continued to measure until the failure of armour slope. The armour layer was reconstructed prior to start of each test series. The test results of 2D flume tests showed that wave overtopping over crablock slope did not vary much between the different test series with same wave steepness. Nevertheless, it was observed that wave overtopping is little bit higher for longer wave period that means for low steepness compared to short period. Based on test results, it was also found that overtopping behaviour does not really change with the change in packing density and also with different placement pattern of armour layer. Regarding to the comparison of relative overtopping rate over crablock armour between test results and empirical prediction, it was found that that empirical equation with assuming roughness factor of 0.45 underestimate the measured wave overtopping over crablock. However, the comparison between the test results on overtopping percentages and estimation by EurOtop (2007) proved that percentage of waves overtopped over crablock can be well predicted by using empirical formula. Furthermore, the measured wave overtopping over crablock slope was found slightly higher in comparison to CLASH (2004) results on other single layer units. This variation was mainly observed for the test results with low wave steepness. Besides relatively low wave steepness, most of the tests on crablock were performed with relatively longer wave periods in comparison to CLASH (2004) which was also one of the triggering factor for higher overtopping over crablock slope compared to CLASH (2004). Moreover, the use of sloping foreshore (1:30) instead of horizontal one by CLASH (2004) might also influence the overtopping behaviour. The 1:30 slope changed the shape of the waves and the waves at the structure toe showed a clear increase in velocity of the wave crest (near or at breaking) The resulting wave overtopping over crablock slope was also compared with the overtopping over xbloc slope measured by DMC (2003). From the comparison, it was found that wave overtopping over crablock is significantly lower compared to xbloc measurements by DMC (2003). Based on the comparison of wave overtopping over different armour slope with and without Ursell parameter, it was recognised that use of the Ursell parameter may explain wave period differences in some cases, but introduces also unexpected differences.Crabloc
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