215 research outputs found

    Lithics from Thung Binh 1 (clockwise from upper left): Short axe, flake tools (photo by author).

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    Lithics from Thung Binh 1 (clockwise from upper left): Short axe, flake tools (photo by author).</p

    Lithics from Thung Binh 3 (clockwise from upper left): Core tool, flake tools (photo by author).

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    Lithics from Thung Binh 3 (clockwise from upper left): Core tool, flake tools (photo by author).</p

    Intrahepatic expression of hepatitis B virus antigens: Effect of hepatitis C virus infection

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    Abstract Coinfection with hepatitis B and C viruses (HBV, HCV) is not uncommon, but the expression of HBV antigens in the liver of patients with concomitant HCV infection has not been investigated. This study aimed to evaluate the effects of concomitant HCV infection on the intrahepatic expression of HBV antigens in chronic hepatitis. HBV surface and core antigens (HBsAg, HBcAg) were immunohistochemically evaluated and semiquantitatively scored in liver biopsy specimens from patients with chronic hepatitis, comprising 17 cases with dual HBV/HCV infection and 25 with HBV infection alone. The prevalence of HBV Ag expression proved significantly lower in the group with dual infection. In the presence of active HBV replication (HBV DNA-positive serum) the prevalence of HBsAg and HBcAg immunoreaction was similar in the two groups, though a significantly lower percentage of cells expressed HBcAg in the group of coinfected patients. HBV Ag was not detected at all among HBV DNA-negative/HCV RNA-positive cases. In conclusion, these observations suggest that HCV might influence HBV antigen expression in the liver and that either partial or complete suppression might occur

    Contemporary Issues in Liver Pathology

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    Verslag behorende bij het processchema: Azijnzuuranhydride uit azijnzuur volgens het keteen-proces

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    Document(en) uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science

    Thung Phudson

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    The author illustrates that the garden of Fortune cape jasmine (Gardenia Jasminoides) --a kind of flower called Phudson in Thai-- was once located in Lopburi near one of the palaces of King Narai. But there is currently no evidence of the flower garden left, apart from records from the French missionary's chronicles

    Kon cha thung Suriyothai

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    The author writes about Prince Chatrichaloem Yukhon, a Thai outstanding filmmaker, and his previous famous films

    Use of a perforated balloon catheter to deliver concentrated heparin into the wall of the normal canine artery

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    A perforated catheter was used to deliver either horseradish peroxidase or fluoresceinated heparin under pressure to the canine arterial wall. Depth of penetration of the media by horseradish peroxidase was dependent on perfusion pressure. At 5 bar pressure for 1 min, the entire media showed a reaction product for horseradish peroxidase. Fluoresceinated heparin delivered under the same conditions could be demonstrated to traverse the entire media as well.A pressure of 5 bars caused medial necrosis at 48 h after perfusion, even when the perfusing solution was saline. (This did not differ from the effect of standard angioplasty at the same pressure.) However, heparin at 5,000 U/ml did not cause medial alteration at 48 h when delivered at the lower pressure of 500 mm Hg. It is feasible to deliver heparin over 1 min in high concentration to the arterial wall by means of this balloon catheter. This method may permit the use of commercially prepared heparin in high concentration as an antiproliferative agent to control the problem of restenosis after angioplasty

    Molecular Signature of Early Hepatocellular Carcinoma

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    The advances in imaging techniques and establishment of screening and surveillance protocols for high-risk populations for hepatocellular carcinoma (HCC) have led to the detection of small hepatic nodules in patients with chronic liver diseases, but in general the prognosis for HCC remains poor. Early detection of HCC or detection of small/early HCC followed by appropriate treatment is the key to significantly alter the prognosis and significantly decrease tumor-related deaths. Recent advances in gene profiling have led to a better understanding in early hepatocarcinogenesis and have suggested several possible molecular signatures which are able to separate early HCCs from their precursors, the dysplastic nodules. The continued search for new and more accurate molecular signatures must be translated into the clinical setting, where they can advance screening and surveillance of high-risk patients in the detection of early HCC.</jats:p
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