62,931 research outputs found
1998 Pollen Calendar - 2-hourly Airborne Pollen Monitoring Station – University of Modena and Reggio Emilia (Botanical Garden/ Geophysical Observatory).
Calendar of the pollen rain from one years - Monitoring Station of Vignola (Modena-Italy
Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example: Breakdown of the multi-shell cytokine network fuels cancer in aged people.
Inflamm-aging is a relatively new terminology used to describe the age-related increase in the systemic pro-inflammatory status of humans. Here, we represent inflamm-aging as a breakdown in the multi-shell cytokine network, in which stem cells and stromal fibroblasts (referred to as the stem cell niche) become pro-inflammatory cytokine over-expressing cells due to the accumulation of DNA damage. Inflamm-aging self-propagates owing to the capability of pro-inflammatory cytokines to ignite the DNA-damage response in other cells surrounding DNA-damaged cells. Macrophages, the major cellular player in inflamm-aging, amplify the phenomenon, by broadcasting pro-inflammatory signals at both local and systemic levels. On the basis of this, we propose that inflamm-aging is a major contributor to the increase in cancer incidence and progression in aged people. Breast cancer will be presented as a paradigmatic example for this relationship
p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes
A wide difference in the susceptibility to undergo in vitro apoptosis exists among individuals, and this fact has potential implications
in predicting the in vivo response to apoptotic agents, such as those employed in chemotherapy. In this report, we addressed
the question whether the natural variability at p53 locus (the proline–arginine substitution at codon 72) affects the capacity
of peripheral-blood mononuclear cells from healthy subjects to undergo in vitro apoptosis in response to the cytotoxic drug cytosine
arabinoside. We found that cells from subjects carrying the arginine/arginine genotype undergo in vitro apoptosis at a higher extent
in comparison to those from arginine/proline subjects. This finding suggests that naturally occurring genetic variability at p53 gene
explains part of the inter-individual difference in the in vitro susceptibility to a chemotherapeutic drug, thus resulting as an eligible predictor marker of in vivo response to chemotherapy and its adverse effects
Cupressaceae/ Taxaceae: 3- Il polline di Cupressaceae negli anni 1990 - 2001 a Vignola.
Andamento polline di Cupressaceae in ari
Cupressaceae/Taxaceae: 2 - Il polline di Cupressaceae e dettaglio su Calocedrus nel 2000 a Modena
Andamento del pollin
Retinoid Receptor Ligands are Potent Anti-inflammatory Agents in Breast Cancer Stem Cells Model
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients
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