1,721,108 research outputs found
Trichoscopy. Illustrated atlas. Ediz. per la scuola
This book is a guide to the trichoscopic diagnosis of the most frequent hair diseases. Rich in photographs, it allows immediate visualization of the trichoscopic signs, useful for a comparison with the real aspects observed during clinical practice.
The pathogenesis of the various signs is indicated so that the reader is able to interpret the symptoms and the extent of the problem in the most appropriate way.
Contains indications on the correct magnifications for optimal visualization of the hair, skin and vessels; and the usefulness of dry or interface trichoscopy.
It is only with knowledge of the physiology and pathology of hair, and with practical experience, that one learns to diagnose and manage alopecia and trichoscopy helps in all three processes
Tricoscopia. Atlante illustrato. Ediz. illustrata
Questo libro è una guida alla diagnosi tricoscopica delle più frequenti malattie dei capelli. Ricco di fotografie, consente un’immediata visualizzazione dei segni tricoscopici, utile per un confronto con gli aspetti reali osservati durante la pratica clinica. Dei diversi segni è indicata la patogenesi affinché il lettore sia in grado di interpretare nel modo più opportuno i sintomi e l’entità del problema. Contiene indicazioni sugli ingrandimenti corretti per la visualizzazione ottimale dei capelli, della cute e dei vasi; e l’utilità della tricoscopia a secco o con interfaccia. È solo con la conoscenza della fisiologia e della patologia dei capelli, e con l’esperienza pratica, che si impara a diagnosticare e gestire le alopecie e la tricoscopia aiuta in tutti e tre i processi
Alopecia areata (AA) and treatment with simvastatin/ezetimibe: Experience of 20 patients
case series to evaluate the effectiveness of simvastatin/ezetimibe in patients with alopecia areat
Visualization of hair bulbs through the scalp: A trichoscopic feature of erosive pustular dermatitis of the scalp
Erosive pustular dermatitis of the scalp (EPDS) typically affects elderly people with scarring alopecia. Videodermoscopy (VD) of the scalp has never been assessed in the diagnosis of EPDS. To evaluate the trichoscopy features of EPDS, we carried out a retrospective analysis of VD images obtained in the scalp of ten patients who affected by EPDS and were compared with those obtained from a series of thirty patients who affected by other type of scarring alopecia. The most specific VD feature was thus represented by evident hair bulb in the scarring scalp, observed in all patients
Tinea Incognita following the Use of an Antipsoriatic Gel
Tinea incognita is a dermatophyte infection of the skin whose clinical presentation has been modified by the misuse of steroids or, as has been described recently, calcineurin inhibitors. We report a case of pustular psoriasis treated with an antipsoriatic cream, composed of topical steroids and a vitamin D3 derivative, which gave rise to a tinea incognita. Our case underlines that clinical features of fungal infection can be modified by the increasing use of self-prescribed topical therapies, usually applied to treat incorrectly 'self-diagnosed' diseases. Moreover, we suggest that a mycological examination should be performed in every atypical presentation of skin lesion, and to rule out tinea pedis, in any disease of the feet that requires topical application of steroids
Early Visible Improvements during K101-03 Treatment: An Open-Label Multicenter Clinical Investigation in Patients with Onychomycosis and/or Nail Psoriasis.
Introduction: Onychomycosis and nail psoriasis can be embarrassing to patients, so improving the appearance of affected nails should be one of the key short-term goals of treatment. Methods: An 8-week open-label multicenter study was conducted to assess whether K101-03, a marketed topical treatment containing propylene glycol, glycerol, urea, and lactic acid, could produce rapid cosmetic improvements in affected nails. Adult patients with a big toenail or thumbnail (the “target” nail) affected by onychomycosis (n = 72) or psoriasis (n = 34) or both (n = 1) applied K101-03 to their affected nails once a day for 8 weeks. During and after treatment, patients rated the overall appearance of their target nail on a 4-point scale. They also assessed whether thickening, discoloration, brittleness, and softness of the target nail had improved since baseline. Adverse events (AEs) that occurred between the first application of K101-03 and the end of treatment were recorded and categorized according to severity and relationship to K101-03. Results: After 8 weeks of K101-03 treatment, 92.2% of patients (95% confidence interval [CI] 87.06-97.40) reported at least some improvement in the target nail. After 1 week of treatment, 78.3% of patients with onychomycosis (95% CI 68.53-87.99) reported at least some improvement in the target nail, and 55.1% of them reported that discoloration of their target nail had improved. Three patients reported a total of 5 AEs, none of which were judged to be related to K101-03. Conclusions: In summary, K101-03 was well tolerated in patients with onychomycosis or nail psoriasis and rapidly improved their nails
Optimal management of nail disease in patients with psoriasis
Bianca Maria Piraccini, Michela Starace Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy Abstract: Psoriasis is a common skin disease, with nail involvement in approximately 80% of patients. Nail psoriasis is often associated with psoriatic arthropathy. Involvement of the nails does not always have relationship with the type, gravity, extension, or duration of skin psoriasis. Nail psoriasis can occur at any age and all parts of the nails and the surrounding structures can be affected. Two clinical patterns of nail manifestations have been seen due to psoriasis: nail matrix involvement or nail bed involvement. In the first case, irregular and deep pitting, red spots of the lunula, crumbling, and leukonychia are seen; in the second case, salmon patches, onycholysis with erythematous border, subungual hyperkeratosis, and splinter hemorrhages are observed. These clinical features are more visible in fingernails than in toenails, where nail abnormalities are not diagnostic and are usually clinically indistinguishable from other conditions, especially onychomycosis. Nail psoriasis causes, above all, psychosocial and aesthetic problems, but many patients often complain about functional damage. Diagnosis of nail psoriasis is clinical and histopathology is necessary only in selected cases. Nail psoriasis has an unpredictable course but, in most cases, the disease is chronic and complete remissions are uncommon. Sun exposure does not usually improve and may even worsen nail psoriasis. There are no curative treatments. Treatment of nail psoriasis includes different types of medications, from topical therapy to systemic therapy, according to the severity and extension of the disease. Moreover, we should not underestimate the use of biological agents and new therapy with lasers or iontophoresis. This review offers an investigation of the different treatment options for nail psoriasis and the optimal management of nail disease in patients with psoriasis. Keywords: biologics, nail psoriasis, topical therapy, systemic therap
PEDUNCULATED GINGIVAL LESIONS IN AN ADOLESCENT BOY
LESIONE PEDULìNOCLATA IN UN ADOLESCENTE QUIZ CAS
Le unghie dei piedi. Manuale pratico per la gestione delle onicopatie. Ediz. ampliata
Le malattie delle unghie rappresentano un settore specialistico della dermatologia e sono spesso poco conosciute. In particolare, le onicopatie dei piedi rappresentano oggi un campo in cui dermatologo e podologo collaborano al fine di garantire un’ottimale gestione del paziente, che può così beneficiare di diagnosi e terapia di competenza specialistica, ma anche di trattamenti periodici da parte del podologo.
L’intento di questo libro è fornire una visione schematica e immediata delle patologie ungueali, facilitata dalla presenza di numerose fotografie, per rendere il lettore in grado di effettuare una pronta diagnosi e gestire il paziente nel modo più opportuno.
In questa seconda edizione è stato aggiunto un focus sulle unghie delle mani, che possono presentare patologie esclusive e diverse da quelle dei piedi
Dermoscopy, reflectance confocal microscopy and optical coherence tomography for the diagnosis of lichen simplex chronicus localized on the scalp
Introduction & Objectives: Lichen simplex chronicus (LSC) is characterized by lichenified plaques that occur as a result of constant scratching or rubbing of the skin. The scalp is one of the most common locations involved by this chronic condition. No data on reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) of LSC on the scalp exist, while the useful of dermatoscopy for the diagnosis of this disease was described in three cases.
The aim of this study was to evaluate features of LSC at dermoscopy, reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) in order to provide a rapid non-invasive bed-side diagnosis.
Materials & Methods: A clinical assessment, digital dermatoscope examination, RCM and OCT were performed in two patients with LSC of scalp. The diagnosis of LSC was confirmed histologically.
Results: We show that dermatoscopy, RCM and OCT can be useful tools for the diagnosis of LSC. We also correlate the dermatoscopic, RCM and OCT signs with the pathological features observed in transversely sectioned scalp biopsies from affected scalp of these two patients.
Conclusions: Dermoscopy, RCM and OCT provide useful information for a rapid diagnosis of LSC of scalp and for the identification of biopsy site
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