1,721,298 research outputs found
Personality traits and attitudes toward the menstrual rhythmicity: a survey conducted in two University Clinics in Northern Italy
No full textNEOADJUVANT CHEMOTHERAPY FOLLOWED BY RADICAL SURGERY VERSUS CONCURRENT CHEMO-RADIOTHERAPY IN THE TREATMENT OF LOCALLY ADVANCED CERVICAL CANCER: A MULTICENTER OBSERVATIONAL RETROSPECTIVE STUDY
No full text[Genital infections as a cause of abortion in the first trimester of pregnancy. Review of the literature].
No full textThe rate of spontaneous abortion from embryo-fetal infection is believed to range from 10 to 15%. This figure, however, is likely to be underestimated because of subclinical abortions occurring at the earliest stages of gestation that go undiagnosed. The actual frequency of infections resulting in 1st trimester spontaneous abortion is therefore unknown, whereas the impact of infectious agents in the TORCH group on the pathogenesis of such event is well known, although the pathogenetic mechanisms are not well understood. A wide range of microorganisms have been isolated by several investigators from the lower genital tract of women with 1st trimester spontaneous abortion. No causative relationship of HIV-1 infection to spontaneous abortion has been established yet. The diagnosis of abortion from infection can only be made retrospectively based on histologic examination of fetal and placental tissue and isolation on culture of the infectious agent assumed to have caused infection
Chlamydia trachomatis and cervical intraepithelial neoplasia.
No full text57 patients with viral condylomata of the uterine cervix and/or cervical intraepithelial neoplasia (CIN) were examined evaluating the presence of Chlamydia Trachomatis (Ct) cervical infection and serum IgG anti-Ct. The prevalence of Ct cervical infection was globally 7.22%, in CIN 3 group the rate was higher (16.67%). In addition, in this group the rate of IgG anti-Ct was significantly higher (66.67% vs 11.76%; p = 0.01) in comparison to the whole group. The role of the association between Human Papillomaviruses and Ct infection was finally discussed
FcyRI (CD64), interleukin 8 and interleukin 17 correlation in pregnancies at risk of pre-term delivery
No full textDealing with premature menopause in women at high-risk for hereditary genital and breast cancer
No full textRisk-reducing salpingo-oophorectomy is the mainstay of ovarian cancer prevention in BRCA mutation carriers. However, premature menopause exerts many short and long-term consequences on the individual health that are preventable with a tailored approach. Even though our level of knowledge on BRCA1 and -2 mutation carriers is still in its infancy, the basic principles governing the management of menopausal symptomatology and the prevention of diseases should be applied, including the use of hormone replacement therapy (HRT), approximately until the age of 50. Indeed, short-term HRT significantly ameliorate quality of life and symptoms associated to vulvo-vaginal atrophy, without displaying an adverse effect on oncologic outcomes in BRCA1 and BRCA2 mutation carriers without a personal history of breast cancer. Premature menopause affects significantly also bone health, cardiovascular parameters and cognition. A standard of care is required in order to identify those women at higher risk of developing chronic conditions at midlife and beyond. Appropriate counseling on both hormonal and non-hormonal treatments is an essential part of a shared decision on the most effective management of women at high-risk for hereditary genital and breast cancer
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