1,721,016 research outputs found
Intraoperative sentinel node detection by an innovative imaging probe.
No full textIntraoperative sentinel node detection by an innovative imaging probe.
Campisi C, Soluri A, Stella S, Valenti G, Scopinaro F.
SourceInstitute of Biomedical Technologies, National Research Council, Rome. [email protected]
Abstract
Intraoperative tumor detection has been used in many applications, and today the sentinel node technique is a widely employed surgical procedure in breast cancer. Different detector systems are employed but several problems have been reported in clinical practice, in particular the difficulty to accurately detect the sentinel node within the axillary soft tissue. The problem is even greater for abdominal and thoracic tumors. We propose an innovative Imaging Probe (IP) able to visualize on a monitor the primary tumor and secondary lesions if appropriately radiolabeled. The IP can be optimally applied for minimally invasive surgery in breast cancer treatment, and a preliminary experience related to 15 patients and 20 sentinel nodes is reported here. We compared the results obtained with the IP to those obtained with an Anger camera and a traditional scintillation detector, and found them to be very promising. In particular the surgeon's work is greatly facilitated by direct visual guidance instead of a generic acoustic signal.
PMID:12369557[PubMed - indexed for MEDLINE
Clinical use of an imaging probe in breast cancer surgery.
No full text1. Tumori. 2002 May-Jun;88(3):S35-7.
Clinical use of an imaging probe in breast cancer surgery.
Scafè R, Soluri A, Amanti C, Burgio N, Capoccetti F, David V, Stella S, Scopinaro F.
ENEA-CR Casaccia, Rome, Italy.
Abstract
AIMS:
Portable cameras allow easy transfer of the detector, and thus of radioisotope imaging, to the operating room. In this paper we describe our preliminary experience in radionuclide imaging of breast cancer with a 22.8 x 22.8 mm(2) field-of-view minicamera called "Imaging Probe" (IP).
METHODS:
Breast cancer detection by IP was performed to guide biopsy, in particular open biopsy, or help fine-needle or core-needle positioning when the main guidance method was ultrasonography or digital radiography. 99mTc Sestamibi (MIBI) was injected 1 h before imaging and biopsy to 14 patients with suspected or known breast cancer. Scintigraphic images were acquired before and after biopsy in each patient. The surgeon was allowed to take into account scintigraphic images as well as previously performed mammograms and ultrasonography.
RESULTS:
High-resolution IP images were able to guide biopsy toward cancer or toward washout zones of cancer which are thought to be chemoresistant in seven patients out of 10. Four patients in whom IP and MIBI were unable to guide biopsy were found not to have cancer.
CONCLUSIONS:
Our study confirms the ability of IP to guide breast biopsy even when our minicamera has to be handled manually by trained physicians during surgery.
PMID: 12365382 [PubMed - indexed for MEDLINE
[Current role of surgery in the combined treatment of neoplastic diseases].
No full textLa chirurgia oncologica, proprio per la sua complessità in relazione ai diversi organi interessati,
a situazioni le più varie e al suo carattere curativo o palliativo, tende non infrequentemente a
basarsi su conoscenze ormai superate dai rapidi progressi scientifici-tecnologici, talora sostenute
da dogmi con pochi fondamenti scientifici.
Proprio riflettendo sugli aspetti più innovativi che hanno caratterizzato in questi ultimi anni
l’evoluzione delle conoscenze sul trattamento multimediale della malattia neoplastica, non possiamo
non riconsiderare il ruolo che in esso attualmente svolge la chirurgia. Tale ruolo ovviamente
si modifica costantemente in relazione ai progressi degli altri trattamenti ed in funzione dei progressi
e limiti della chirurgia stessa
Probe for detection of gamma rays for laparoscopy or intracavitary tumour localization.
No full textEuropean Patent Offic
Attuale ruolo della chirurgia nel trattamento multimediale della malattia neoplastica
No full textG Chir. 2008 Jan/Feb;29(1/2):5-7
Descrizione: Gamma camera miniaturizzata ad alta risoluzione spaziale.
No full textUfficio ITA brevett
Miniaturized gamma camera with very high spatial resolution.
No full textFederal Patent Bureau (U.S.A
Mammotone breast cancer biopsy: combined guided with X-ray stereotaxis and imaging probe
No full text
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