1,720,964 research outputs found
Valore diagnostico e prognostico del coinvolgimento del sistema nervoso in pazienti con infezione da HIV-1.
No full textCorrelati elettrofisiologici (EEG e BAEP) durante ipossia ipossica nel coniglio in condizioni di mantenuta perfusione cerebrale
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ELECTROPHYSIOLOGICAL STUDY (VEP,BAEP) IN HIV-1 SEROPOSITIVE PATIENTS WITH AND WITHOUT AIDS
No full textOne hundred-twenty nine HIV-1 seropositive patients (39 females, 90 males) were studied by means of pattern visual evoked potential (VEP) and brainstem auditory evoked potential (BAEP) recording. Utilizing the criteria of the Centers for Disease Control the patients were clinically defined and then subdivided into four groups : group A included patients of category II (n : 11); group B patients of category III (n : 29); group C patients of category IVa and IVc2 (n : 55) and group D patients belonging to the other subgroups of category IV (n : 34). EP were altered in 26.35% of the entire group with a marked prevalence of BA EP alterations (21.7%) rather than of VEP (4.65%). A considerable amount of BA EP abnormalities (24.13%) were found in patients with persistent generalized lymphadenopathy (group B). A significant increase of BAEP mean interpeak latencies were observed in group B, C, D patients when compared with those of the control group. On the whole, EP were altered in 20.65% of the neurologically asymptomatic patients. EP alterations may precede any clinical manifestation and can be found during the earlier phases of HIV-1 infection
Charcot-Marie-Tooth disease in Molise, a central-southern region of Italy: An epidemiological study
No full textAn epidemiological survey of Charcot-Marie-Tooth disease (CMT) was conducted in Molise, a central-southern region of Italy, from March 1998 to June 2000. Fifty-eight cases of CMT in 13 unrelated families were identified within the selected area. The prevalence of all subtypes of CMT was 17.5/100,000. All families underwent a biomolecular analysis to disclose the duplication at gene locus 17p11.2 in order to ascertain the diagnosis of CMT type 1A. Our data revealed that 64% of all the observed patients had CMT1A, thus confirming the high prevalence of duplication of the 17p11.2 locus. Copyright (C) 2002 S. Karger AG, Basel
Studio dei potenziali evocati multimodali in pazienti in differenti stadi dell'infezione da HIV-1.
No full textEffects of spontaneous chronic hypoglycemia on central and peripheral nervous system in insulinoma patients before and after surgery: a neurophysiological follow-up.
No full textLow dosage clozapine effects on L-dopa induced dyskinesias in parkinsonian patients
No full textObjectives - The aim of this study was to investigate the clinical efficacy of clozapine, an atypical neuroleptic, on L-dopa induced dyskinesias of Parkinson's disease. Material and methods - In an open study, a group of 10 PD patients was treated with low dosage clozapine (mean 30 mg/day) for a 4-month period and L-dopa dyskinesias were evaluated in basal conditions and during clozapine treatment after the usual morning dose of clozapine. We utilized the AIMS for evaluation of dyskinesias and UPDRS for the assessment of motor performances. Results - Clozapine produced a significant (P<0.05) reduction of dyskinesias 1 week after the therapy onset. This effect was more pronounced at the end of the 2nd week and remained stable through the following months. We did not observe significant variations of motor performances. Conclusion - A low dose of clozapine appears to be beneficial for patients with L-dopa induced dyskinesias that do not respond to other drugs and therapeutic measures
Prognostic value of early auditory evoked potentials (BAEPS) in experimental hypoxia in the rabbit.
No full textLa neuromielite ottica: Sindrome o malattia?
No full textAbstract
The association of unilateral or bilateral optic neuritis and acute or subacute transverse myelitis is known as neuromyelitis optica. It is a rare demyelinating disorder of unknown aetiology, which rarely occurs in western countries. Since its first descriptions (Devic, 1894) II, the problem concerning its nosographic position in the spectrum of the demyelinating diseases is at the present time unresolved, mainly regarding those cases presenting also cerebral involvement. We presented a longitudinal study of a case of neuromyelitis optica who suddenly developed cerebral signs such as delirium followed two weeks later by an episode of blurred vision and pyramidal weakness to the lower limbs. Five years later, the patient's status consisted of a spastic paraparesis along with an optic atrophy. At the onset, the cerebrospinal fluid analysis disclosed lymphocytic pleocytosis, moderate increase in protein, blood-brain barrier damage and oligoclonal bands which were successively normalized. Serial MRI revealed stable disseminated demyelinating areas. The relationship between neuromyelitis optica and demyelinating diseases is discussed hypothesizing the existence of a wide spectrum of the same disease group ranging from multiple sclerosis to neuromyelitis optica
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