19,850 research outputs found
Topical chemotherapy for ocular surface squamous neoplasia: current status.
No full textBr J Ophthalmol. 2010 May;94(5):532-5. Epub 2009 Sep 23.
Topical chemotherapy for ocular surface squamous neoplasia: current status.
Sepulveda R, Pe'er J, Midena E, Seregard S, Dua HS, Singh AD.
SourceDepartment of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Abstract
Although there are no randomised trials directly comparing topical chemotherapeutic agents mitomycin-C, 5-fluorouracil, and interferon-alpha2b, published studies indicate equal efficacy of these agents for treatment of non-invasive ocular surface squamous neoplasia (80%-88%). 5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient.
PMID: 19776089 [PubMed - indexed for MEDLINE
Book Review: "Mystic Echoes: Stories Rooted in Sikh Spiritual Realms" (Book Author: Dr. Devinder Pal Singh; Book Reviewer: Prof. Hardev Singh Virk)
No full textDr. Devinder Pal (DP) Singh joined the Physics Department in 1983 as an Ad-hoc Lecturer to teach Physics and complete his doctorate degree in Physics (Acoustics). I found him as a dedicated teacher and researcher. Upon moving to Canada as an immigrant, he initiated a new venture, the “Center for Understanding Sikhism”. A similar organization, the “Institute for Understanding Sikhism,” was established in 1999 by Dr. D. S. Chahal in Montreal. I was perplexed as to why a hardcore physicist was meddling in Sikhism. My curiosity was satisfied after reviewing his book, “Science and Sikhism: Conflict or Coherence.” I started rating him as one of the greatest exponents of Sikhism (Sikhi) in the modern age.
The Foreword “A Sacred Mirror: Seeing Ourselves Through Sikh Narratives” is by Bhai Harbans Lal, Ph.D., D. Litt (Hons). Bhai Lal appreciates the technique used by D. P. Singh: “It brings the living essence of Gurbani into our day-to-day existence. These are not abstract theological exercises, nor are they simply nostalgic tales of rural life. Instead, they are powerful spiritual parables, immersive narratives that reveal how the universal truths embedded in Sikh teachings manifest in the hearts, struggles, and transformations of everyday people”.
The author introduces his UNIQUE work in the Preface “Bridging the Temporal and the Timeless” as follows: “The stories in Mystic Echoes: Stories Rooted in Sikh Spiritual Realms emerge from the convergence of profound spiritual reflection, lived experience, and the enduring resonance of Sikh philosophy. They are not merely works of fiction, but narrative expressions of spiritual truths rooted in the teachings of the Sikh Gurus”. Further, D. P. Singh explains the relevance and importance of chosen topics: “Each story in Mystic Echoes is an attempt to explore a specific spiritual theme from within the Sikh tradition: Naam (Divine Name), Hukam (Divine Order), Haumai (Ego), Maya (Worldly Illusion), Raza (Divine Will), Sunn (Primal Void), Sahaj (Equilibrium), Bhaau and Bhae (Devotional Love and Reverent Fear), Nadar (Grace), Wismad (Wondrous Bliss), Anhad Naad (Unstruck Melody), Chautha Pad (Fourth State), Dasam Duar (Tenth Gate), Panj Tat (Five classical elements), and Daya (Compassion) among others
Book Review: "Mystic Echoes: Stories Rooted in Sikh Spiritual Realms" (Book Author: Dr. Devinder Pal Singh; Book Reviewer: Prof. Hardev Singh Virk)
No full textDr. Devinder Pal (DP) Singh joined the Physics Department in 1983 as an Ad-hoc Lecturer to teach Physics and complete his doctorate degree in Physics (Acoustics). I found him as a dedicated teacher and researcher. Upon moving to Canada as an immigrant, he initiated a new venture, the “Center for Understanding Sikhism”. A similar organization, the “Institute for Understanding Sikhism,” was established in 1999 by Dr. D. S. Chahal in Montreal. I was perplexed as to why a hardcore physicist was meddling in Sikhism. My curiosity was satisfied after reviewing his book, “Science and Sikhism: Conflict or Coherence.” I started rating him as one of the greatest exponents of Sikhism (Sikhi) in the modern age.
The Foreword “A Sacred Mirror: Seeing Ourselves Through Sikh Narratives” is by Bhai Harbans Lal, Ph.D., D. Litt (Hons). Bhai Lal appreciates the technique used by D. P. Singh: “It brings the living essence of Gurbani into our day-to-day existence. These are not abstract theological exercises, nor are they simply nostalgic tales of rural life. Instead, they are powerful spiritual parables, immersive narratives that reveal how the universal truths embedded in Sikh teachings manifest in the hearts, struggles, and transformations of everyday people”.
The author introduces his UNIQUE work in the Preface “Bridging the Temporal and the Timeless” as follows: “The stories in Mystic Echoes: Stories Rooted in Sikh Spiritual Realms emerge from the convergence of profound spiritual reflection, lived experience, and the enduring resonance of Sikh philosophy. They are not merely works of fiction, but narrative expressions of spiritual truths rooted in the teachings of the Sikh Gurus”. Further, D. P. Singh explains the relevance and importance of chosen topics: “Each story in Mystic Echoes is an attempt to explore a specific spiritual theme from within the Sikh tradition: Naam (Divine Name), Hukam (Divine Order), Haumai (Ego), Maya (Worldly Illusion), Raza (Divine Will), Sunn (Primal Void), Sahaj (Equilibrium), Bhaau and Bhae (Devotional Love and Reverent Fear), Nadar (Grace), Wismad (Wondrous Bliss), Anhad Naad (Unstruck Melody), Chautha Pad (Fourth State), Dasam Duar (Tenth Gate), Panj Tat (Five classical elements), and Daya (Compassion) among others
Link stability estimation based on link connectivity changes in mobile ad-hoc networks
No full textDear Wang,
Re: Link Stability Estimation Based on Link Connectivity Changes in Mobile Ad-hoc Networks
I have not been able to assess if this is an author version peer-reviewed or is it an author version non peer reviewed. Could you please clarify this so I can proceed to add your paper to Spiral. Spiral digital repository only accept peer-reviewed papers.
30/11/12 author has confirmed peer reviewe
INFRARED THERMOTHERAPY. FROM LABORATORY TO CLINIC
No full textThermotherapy by the transpupillary route is an effective outpatient eye-salvaging therapy for intraocular tumors. It does not require surgery, it can be repeated, and it does not affect the healthy structures of the eye. Thermotherapy by the transscleral route is under investigation and may have potential in the treatment of choroidal melanomas. The indications for chemoreduction, thermochemotherapy, and thermotherapy for retinoblastoma remain under investigation
When Peer-to-Peer comes Face-to-Face: Collaborative Peer-to-Peer Computing in Mobile Ad hoc Networks
No full textThis paper motivates and describes the notion of mobile ad hoc information systems. Such a system consists of a decentralized and self-organizing network of autonomous, mobile devices that interact as peers. Connectivity is determined by distance between devices; as hosts change their physical location they establish pair-wise communication links based on mutual proximity. We describe application scenarios for mobile ad hoc information systems and identify technical challenges of a generic software infrastructure. Moreover, we present the goals and architecture of Proem, a peer-to-peer system and development platform for mobile ad hoc applications. Proem has successfully been used as instructional tool in an advanced software engineering course on peer-to-peer computing
Performance Evaluation for Ad hoc Routing Protocol in Vehicular Ad hoc Network (VANET)
No full textIn this paper we researched about different ad hoc routing protocols for VANET. The main aim of our study was to identify which ad hoc routing technique has better execution in highly mobile environment of VANET. To measure the performance of routing protocols in VANET, we considered two different situations i.e. city and highway. Routing protocols were selected carefully after carrying out literature review. The selected protocols were then evaluated through simulation in terms of performance metrics i.e. throughput and packet drop. From results, we observe that A-STAR shows better performance in form of high throughput and low packet drop as compare to AODV and GPSR in city environment, while GPSR shows better performance as compare to AODV in both highway and city environment of VANET
Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration.
No full textOBJECTIVE: To quantify the regional and global cerebral atrophy rates and assess acceleration rates in healthy controls, subjects with mild cognitive impairment (MCI), and subjects with mild Alzheimer disease (AD). METHODS: Using 0-, 6-, 12-, 18-, 24-, and 36-month MRI scans of controls and subjects with MCI and AD from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, we calculated volume change of whole brain, hippocampus, and ventricles between all pairs of scans using the boundary shift integral. RESULTS: We found no evidence of acceleration in whole-brain atrophy rates in any group. There was evidence that hippocampal atrophy rates in MCI subjects accelerate by 0.22%/year2 on average (p = 0.037). There was evidence of acceleration in rates of ventricular enlargement in subjects with MCI (p = 0.001) and AD (p < 0.001), with rates estimated to increase by 0.27 mL/year2 (95% confidence interval 0.12, 0.43) and 0.88 mL/year2 (95% confidence interval 0.47, 1.29), respectively. A post hoc analysis suggested that the acceleration of hippocampal loss in MCI subjects was mainly driven by the MCI subjects that were observed to progress to clinical AD within 3 years of baseline, with this group showing hippocampal atrophy rate acceleration of 0.50%/year2 (p = 0.003). CONCLUSIONS: The small acceleration rates suggest a long period of transition to the pathologic losses seen in clinical AD. The acceleration in hippocampal atrophy rates in MCI subjects in the ADNI seems to be driven by those MCI subjects who concurrently progressed to a clinical diagnosis of AD
Rajpardia BICKEL & MARTIN & AGNIHOTRI & SINGH 2022, gen. nov.
No full textGenus Rajpardia Bickel gen. nov. Type species. Rajpardia grimaldii Bickel sp. nov. Etymology. Rajpardia is a derived from the place name Rajpardi, a quarry where Cambay amber occurs. The gender is feminine. Diagnosis. [This generic diagnosis is based on a single damaged male specimen and emphasizes characters considered to be of generic importance.] Body length about 1.0 mm; head large; postcranium apparently concave; postpedicel reniform, and partially enclosing distal pedicel; arista apical; TI with distinct row of 3 short ad setae along distal third and some short apicoventral setae; both FII and FIII with anterior preapical seta; epandrium rounded subrectangular; hypandrium forming rounded hood; surstylus short and triangular; cercus digitiform with apical toothlike seta.Published as part of BICKEL, DANIEL J., MARTIN, JOHN, AGNIHOTRI, PRIYA & SINGH, HUKAM, 2022, Dolichopodidae (Diptera) from the Eocene amber deposits of Cambay and Kutch Basins, India, pp. 475-486 in Palaeoentomology 5 (5) on page 483, DOI: 10.11646/palaeoentomology.5.5.9, http://zenodo.org/record/733377
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