1,721,051 research outputs found
The Impact of the Loop Electrosurgical Excisional Procedure for Cervical Intraepithelial Lesions on Female Sexual Function
No full textIntroduction. Very limited knowledge exists concerning the impact of Loop Electrosurgical Excisional Procedure (LEEP) on female sexual function in women with cervical intraepithelial neoplasia Aim. To investigate sexual function in women who underwent LEEP for the treatment of cervical intraepithelial lesions, using a validated questionnaire (Female Sexual Function Index [FSFI]). Main Outcome Measures. FSFI questionnaire on six domains of female sexuality (desire, arousal, lubrication, orgasm, satisfaction, and pain). Methods. Consecutive sexually active women, who underwent LEEP for the treatment of cervical intraepithelial neoplasia were enrolled in this study. All women were asked to complete a copy of FSFI questionnaire, at the time of LEEP and after 6 months. We finally compared the results of the pre-LEEP questionnaire and the post-LEEP questionnaire for each patient. Results. A total of 67 sexually active women undergoing LEEP for the treatment of cervical intraepithelial lesions were enrolled. Nine of these patients (13.4%) completed only the questionnaire regarding their sexual function before LEEP; thus we did not include them for final analysis. In our study population, data showed a sexual function overall unchanged after LEEP; only the variable "desire" (sexual interest) became significantly worse (P = 0.02). Conclusions. LEEP for the treatment of cervical intraepithelial lesions doesn't affect women's sexuality, when compared with sexual function before surgery. In our study, all FSFI sexual function domains but desire, did not show significant change after LEEP. Serati M, Salvatore S, Cattoni E, Zanirato M, Mauri S, Siesto G, Cromi A, Ghezzi F, and Bolis P. The impact of the Loop Electrosurgical Excisional Procedure for cervical intraepithelial lesions on female sexual function. J Sex Med 2010;7:2267-2272
Preliminary study of Saccharomyces cerevisiae from wines produced in traditional Georgian amphoras
No full text
Characterization of Saccharomyces cerevisiae strains involved in spontaneous fermentation of traditional Georgian wines
No full text
Risk factors for recurrence of genital prolapse
No full textPurpose of review To review the available evidence regarding those risk factors potentially predicting a recurrence of pelvic organ prolapse (POP). Recent findings POP is a very common condition in parous women, requiring very often a surgical treatment which may need to be repeated in up to 29% of cases. In the past few years, researchers have focused their attention on the evaluation of risk factors involved in either POP development or recurrence. Recent papers have reported the importance of genetic factors that could be responsible for an inherited weakness of the pelvic floor, predisposing to POP occurrence and/or recurrence. Moreover, a history of genital prolapse at the time of an elective hysterectomy, as well as an inappropriate reconstructive surgical procedure, can predict and be associated with POP development. Summary POP recurrence can be associated with a combination of predisposing, inciting, and intervening factors. Based on actual knowledge, it is not possible to weight or score the importance of each single risk factor reported in literature for the development of POP recurrence. Larger series (collected with validated diagnostic and therapeutic tools) and longer follow-up are, therefore, needed to draw definitive conclusions on this issue
Female Urinary Incontinence at Orgasm: A Possible Marker of a More Severe Form of Detrusor Overactivity. Can Ultrasound Measurement of Bladder Wall Thickness Explain It?
No full textIntroduction. Coital incontinence (CI) during orgasm is a form of urinary incontinence possibly because of detrusor overactivity (DO), as the underlying pathophysiological condition. Women with this symptom usually show a pharmacological lower cure rate than those with DO alone. The ultrasound measurement of the bladder wall thickness (BWT) allows an indirect evaluation of detrusor muscle thickness, giving a potential index of detrusor activity. Aim. We wanted to understand if CI at orgasm could be a marker of severity of DO by comparing BWT in women with both DO and CI at orgasm vs. women with DO alone. In addition we aimed to confirm if CI during orgasm is related to antimuscarinics treatment failure. Methods. This is a prospective cohort study performed in two tertiary urogynecological referral departments, recruiting consecutive patients seeking treatment for symptomatic DO. Main Outcome Measures. All patients were thoroughly assessed including physical examination, urodynamic evaluation, and BWT measurement according to the International Continence Society/International Urogynecological Association and ICI recommendations. Solifenacine 5 mg once daily was then prescribed and follow-up was scheduled to evaluate treatment. Multiple logistic regression (MLR) was performed to identify risk factors for treatment failure. Results. Between September 2007 and March 2010, 31 (22.6%) and 106 (77.4%) women with DO with and without CI at orgasm were enrolled. Women complaining of CI at orgasm had significantly higher BWT than the control group (5.8 +/- 0.6 mm vs. 5.2 +/- 1.2 mm [P = 0.007]). In patients with CI at orgasm, the nonresponder rate to antimuscarinics was significantly higher than controls (P = 0.01). After MLR, CI at orgasm was the only independent predictor decreasing antimuscarinics efficacy (odds ratio [OR] 3.16 [95% CI 1.22-8.18], P = 0.02). Conclusions. Women with DO and CI at orgasm showed a significantly higher BWT values and worse cure rates than women with DO alone. CI at orgasm could be a marker of a more severe form of DO. Serati M, Salvatore S, Cattoni E, Siesto G, Soligo M, Braga A, Sorice P, Cromi A, Ghezzi F, Cardozo L, and Bolis P. Female urinary incontinence at orgasm: A possible marker of a more severe form of detrusor overactivity. Can ultrasound measurement of bladder wall thickness explain it? J Sex Med 2011;8:1710-1716
- …
