21,390 research outputs found
The modern bowel preparation in colonoscopy
No full textAdequate bowel preparation is essential for optimal colonoscopy. Suboptimal bowel preparation occurs in 25percent to 40percent of cases and is associated with canceled procedures, prolonged procedure time, incomplete examination, increased cost, and missed pathology. There are several effective formulations for colon cleansing with a good safety profile. Split dosing should be implemented whenever possible in an effort to enhance tolerance and adherence, and improve mucosal visibility and overall quality of the examination. 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Effects of intradermal injection of atrial natriuretic peptide.
No full textAtrial natriuretic peptide (ANP) causes mast cell degranulation in rats in vivo and in vitro but is bronchodilator in humans. The aim of this study was to investigate the wheal and flare dose-response to intradermal injection of alpha-human ANP in normal humans. Eight normal subjects received five 30 microliters injections containing 1, 10, 39, 78, 117 pmol ANP and one each of normal saline, histamine 675 pmol and substance P 30 pmol. Maximum ANP flare response was greater but not significantly than that to saline at 1.55 +/- 0.6 (mean +/- s.e. mean) compared with 0.42 +/- 0.17 cm2, but much less than to histamine 9.86 +/- 0.97 or to substance P 12.5 +/- 1.2. Maximum ANP wheal response was significantly greater than that to saline at 0.38 +/- 0.08 compared with 0.18 +/- 0.05 cm2 (difference between means 0.20, 95% CI 0.05, 0.35), but much less than to histamine 0.75 +/- 0.06 or to substance P 1.05 +/- 0.08 cm2. No dose-response to ANP was demonstrated, though responses to the highest dose differed significantly from those to the lowest dose studied. We conclude that human cutaneous responses to ANP differ from those of animals and that the skin is less responsive than other tissues in humans
Recurrent massive haemorrhage from an endoscopically inevident isolated rectal varix
No full textAnorectal varices are identified endoscopically in up to 40percent of patients with liver cirrhosis [Misra SP, Dwivedi M, Misra V. Prevalence and factors influencing haemorrhoids, anorectal varices, and colopathy in patients with portal hypertension. Endoscopy 1996;28:340-5] but are an infrequent cause of bleeding and their management remains controversial. We present a patient with chronic hepatitis C virus infection who developed recurrent haemorrhage from an isolated, endoscopically inevident rectal varix in the absence of clinical or endoscopic evidence of portal hypertension. The difficulties in diagnosis and management of anorectal varices are highlighted. © 2006 Editrice Gastroenterologica Italiana S.r.l.Dhiman RK, 1999, GASTROINTEST ENDOSC, V49, P218, DOI 10.1016-S0016-5107(99)70490-6; HASKAL ZJ, 1994, RADIOLOGY, V191, P183; Hidajat N, 2002, AM J ROENTGENOL, V178, P362; Kojima Takayuki, 1996, Japanese Journal of Gastroenterology, V93, P114; Misra SP, 1996, ENDOSCOPY, V28, P340, DOI 10.1055-s-2007-1005477; Misra SP, 2002, ENDOSCOPY, V34, P195; Misra SP, 1999, ENDOSCOPY, V31, P741; POLIO J, 1986, SEMIN LIVER DIS, V6, P318, DOI 10.1055-s-2008-1040614; Sato T, 2003, HEPATOL RES, V27, P158, DOI 10.1016-S1386-6346(03)00203-1; Sharara AI, 2001, NEW ENGL J MED, V345, P669, DOI 10.1056-NEJMra003007; WANG M, 1985, AM J GASTROENTEROL, V80, P779; WAXMAN JS, 1984, DIS COLON RECTUM, V27, P749, DOI 10.1007-BF02554608; Yamanaka T, 2002, HEPATO-GASTROENTEROL, V49, P941; YEH T, 1994, GASTROENTEROLOGY, V107, P116532
Angiomyolipoma of the colon
No full text[No abstract available]Chen JS, 2003, DIS COLON RECTUM, V46, P547, DOI 10.1097-01.DCR.0000059656.11419.6F; HIKASA Y, 1989, Gastroenterologia Japonica, V24, P407; Maesawa C, 1996, AM J GASTROENTEROL, V91, P1852; Maluf H, 1999, MODERN PATHOL, V12, P113220
An unusual cause of jejunojejunal intussusception
No full text[No abstract available]Bays D, 2004, DIGEST DIS SCI, V49, P1677, DOI 10.1023-B:DDAS.0000043385.44842.c8; SHIMER GR, 1984, AM J CLIN PATHOL, V81, P7080
Protecting Animals 36: Author Witi Ihimaera
No full textIn this very special episode of Knowing Animals I am joined by beloved New Zealand author Witi Ihimaera. Witi has written many books featuring nonhuman animals. He offers us a non-colonial lens through which to think about the human/nonhuman relationship
The usefulness of PPD testing in inflammatory bowel disease patients before infliximab therapy
No full text[No abstract available][Anonymous], 2000, AM J RESP CRIT CARE, V161, pS221; Mow WS, 2004, CLIN GASTROENTEROL H, V2, P309, DOI 10.1053-S1542-3565(04)00060-6; Uthman I, 2004, CLIN RHEUMATOL, V23, P279, DOI 10.1007-s10067-004-0873-z21
Solitary rectal ulcer syndrome: Endoscopic spectrum and review of the literature
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Endoscopy in the patient on antithrombotic therapy
No full textPURPOSE OF REVIEW: The management of antithrombotics during the periendoscopic period is a common clinical problem. This review focuses on recent literature addressing this issue, primarily on articles published from 2009 to 2012. RECENT FINDINGS: A large proportion of the studies retrieved focused on the effect of antithrombotics on bleeding risk following diagnostic endoscopy, polypectomy, endoscopic mucosal resection, and submucosal dissection, whereas studies involving other endoscopic procedures were scarce. Recent American and European guidelines direct the management of antithrombotic therapy in patients undergoing endoscopy according to the procedure's risk of bleeding and the patient's thromboembolic risk. The difficulty in determining a priori the need for endotherapy and hence appropriate classification of risk of bleeding prior to the procedure is a potential limitation of such classification. Moreover, most studies have primarily addressed the risk of immediate or early bleeding by proposing interruption of antithrombotic therapy prior to endotherapy, and few have focused on the risk of delayed bleeding and the optimal time for resumption of these agents following high-risk procedures. SUMMARY: Management of patients on antithrombotics remains complex, especially in high-risk settings. Existing guidelines are valuable but should not be a substitute for a careful personalized risk assessment strategy involving patient and physician. 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Gastric bezoar creating a ball-valve effect
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