1,721,103 research outputs found

    New association of surfactants for the production of food and cosmetic nanoemulsions: preliminary development and characterization

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    A new nanoemulsifing system has been developed. This study refers to an innovative association of polysorbate 80 and palmitic ester of l-ascorbic acid for the production of good stability and very thin nanostructured emulsions with average micellar diameter size ranging from 100 to 300 nm. This system has showed to be very performing to create nanoemulsions with moderate stirring rate and warming regimen thanks to the high efficiency of the association between ascorbyl palmitate and polysorbate-80 (PS-80). This nanoemulsified system is very easy to achieve and shows a very good capability to encapsulate several substrates of both nutritional and cosmetic usage such as melatonin, resveratrol, essential oils and steroidic terpenes such as boswellic acids and others. This system has been optimally applied to nutraceutical and cosmetic formulations and particularly to develop sprayable sublingual delivery systems for melatonin and the aforesaid molecules. This study describes developing and analytical characterization of this system containing melatonin

    Microparticles of epidermal lipids containing polyalcohol for the preparation of cosmetic or pharmaceutical compositions

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    The present invention relates to solid microparticles for preparing cosmetic or pharmaceutical compositions to restore skin integrity, promoting rehydration, maintaining hydration and attenuating and preventing roughness. The solid microparticles of the invention contain epidermal lipids, such as cholesterol, ceramides and fatty acids and a polyalcohol, preferably mannitol. The invention also relates to a process for preparing said microparticles by spray- drying. The solid microparticles of the invention are particularly advantageous because they are stable and may be incorporated in excipients and/or carriers for cosmetic or pharmaceutical use, without affecting flowability and without imparting oiliness to the finished product
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