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Aortic regurgitation in athletes. Pieces of the puzzle we have so far omitted
The prevalence of valvular heart disease (VHD) rises with age, reaching 11.7% in individuals older than 75 years.1 In young individuals, VHD is usually related to the presence of a congenital valve abnormality, as bicuspid aortic valve (BAV) or mitral valve prolapse. This is also the case for athletes, where in the presence of these abnormalities few restrictions exist in eligibility
for competitive sports participation, even if a strict follow-up would be desirable. BAV is the most common congenital valve abnormality (1%) found in the general population and in athletes. BAV is more prevalent in males and it can lead to aortic regurgitation (AR), aortic stenosis and/or aortic root dilation. At present, no definitive studies have proved that intensive
sports participation could worsen the progression of BAV and limited data are available on athletes
The B-bar method and the limitation principles
The generalized elastic material provides a reference model to cast in a unitary framework many structural models which are based on nonlinear monotone multivalued relations such as viscoelasticity, plasticity and unilateral models. The modified forms of the Hu-Washizu and Hellinger-Reissner principles and the displacement-based variational formulation are recovered for the generalized elastic material starting from a functional in the complete set of state variables. The related limitation principles are derived and their specialization to elasticity and elastoplasticity with mixed hardening are provided. It is shown that the interpolating fields for the pressure and the volumetric strain usually adopted in the B-bar method lead to a limitation principle. Accordingly the same elastic and elastoplastic solutions can be obtained by means of an approximate mixed displacement⧸pressure variational principle. A second application is concerned with the conditions ensuring the coincidence of the solutions between an approximate two-field mixed formulation and the displacement-based method. Numerical examples are provided to show the coincidence of the solutions obtained from different mixed finite element formulations, in elasticity or elastoplasticity, under the validity of the limitation principles
Elementi indicativi per la determinazione e l'applicazione di un valore di riferimento per l'1-idrossipirene urinario
Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract (LUTS) and benign prostatic hyperplasia (BPH)
Accordion effect of left anterior descending coronary artery after successful stent implantation
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