1,721,056 research outputs found
Esposizione a polveri sottili ed effetti termine. dallo studio di popolazioni a quello di individui
No full textPREVALENCE AND RISK FACTORS OF LONG-COVID-19 SYNDROME IN HEALTH CARE WORKERS: A MULTI-CENTRE STUDY FROM NORTH-EASTERN ITALY, ORCHESTRA PROJECT WORKING GROUP
No full textPREVALENCE AND RISK FACTORS OF LONG-COVID-19 SYNDROME IN HEALTH CARE WORKERS: A MULTI-CENTRE STUDY FROM NORTH-EASTERN ITALY, ORCHESTRA PROJECT WORKING GROUP / Cegolon, Luca; Sansone, Donatella; Tassinari, Alice; Murgia, Nicola; Monaco, Maria Grazia Lourdes; Spiteri, Gianluca; Modenese, Alberto; Gobba, Fabrizio Maria; Pavanello, Sofia; Liviero, Filippo; Scapellato, Maria Luisa; Porru, Stefano; Filon, Francesca Larese. - In: OCCUPATIONAL MEDICINE. - ISSN 0962-7480. - 74:Supplement_1(2024), pp. 0-0. (Intervento presentato al convegno 34th International Congress on Occupational Health ICOH 2024 tenutosi a Marrakesh (Morocco) nel 28th April-3rd May 2024) [10.1093/occmed/kqae023.0452]
Esposizione a inquinanti negli ambienti confinati: valutazione critica e considerazioni operative.
No full textSignificato e ruolo dei valori guida nella valutazione del rischio chimico [Relevance and role of guideline values for chemical risk assessment.]
No full textGuideline values have been defined by the ad hoc S.I.M.L.I.I. Working Group as "the level of a risk factor, previously established for an environmental or biological context, to which the levels actually measured for/in the workers should be compared, in order to assess their degree of exposure". Guideline values include limit values, action levels and reference values, and may refer to an environmental or biological matrix. The present paper aims to discuss the methodologies currently used for the definition of the most relevant guideline and limit values at the national and international level, with a particular attention to those used in the European Union (OEL). It is concluded that a correct use of guideline values represents a fundamental tool for both the assessment and the management of chemical risk in workers exposed to toxic and/or carcinogenic substances
Il lavoro a turni: risultati preliminari di una ricerca sui disagi e le patologie riscontrate tra il personale infermieristico del presidio ospedaliero di Treviso
No full textOccupational exposure to anaesthetic gases and urinary excretion of D-glucaric acid
No full textAbstract
In order to ascertain whether the urinary excretion of D-glucaric acid (DGA) might be a suitable biomarker of effect in monitoring workers exposed to anaesthetic gases, we measured DGA before and after an operating session (and, in some workers, before and after a 2-week vacation) in 229 workers of surgical units and in 229 controls. In the former, we also measured urinary levels of nitrous oxide (N2O) and isoflurane after at least 4 h of exposure. For all subjects, information on age, smoking habits, daily intake of alcohol, coffee, and drugs, history of liver or kidney disease was collected. Study subjects were ranked according to: exposure (class 0: subjects not exposed; class 1: N2O 1 μg 1-1; class 3: N2O >27 μg l-1 and isoflurane 27 μg l-1 and isoflurane >1 μg l-1); general habits; and DGA (two groups, below and above the arbitrary cut-off value of 3.5 mmol mol-1 creatinine). The relative risk of presenting high DGA excretion was estimated through the Odds Ratio (OR) and 95% Confidence Intervals (CI). In univariate analysis, ORs increased from class 1 (lowest exposure) to class 4 (highest exposure) and with increases in coffee and cigarette consumption. The ORs adjusted for sex, age, creatinine, and alcohol and coffee intake, conventionally 1.0 in the control group, were 0.68 (CI=0.33-1.38), 2.68 (CI=1.36-5.27), 2.68 (CI=1.21-4.90) and 3.73 (CI=1.51-9.18) respectively in exposure classes 1, 2, 3 and 4. By contrast, individual levels of DGA did not correlate with urinary concentrations of anaesthetic gases. Moreover, no significant differences in DGA levels were observed between urine samples taken before and immediately after a workshift, nor between samples collected before and after at least 2 weeks vacation. In conclusion, DGA excretion cannot be used as an individual biomarker of effect in workers exposed to anaesthetic gases. Since effects on hepatic function were not found at lower concentrations (exposure class 1), the currently adopted threshold limits (isoflurane: 1 μg 1-1; and N2O: 27 μg 1-1) appear sufficiently protective
A longitudinal study for investigating the exposure level of anesthetics that impairs neurobehavioral performance.
No full textAbstract
There is conflicting evidence on the level of anesthetics that impairs neurobehavioral performance, leading to differences in exposure standards (25 or 50 ppm for N(2)O). Thirty-eight operating room nurses and 23 unexposed nurses were asked to provide information on confounding variables: age, gender, years of schooling, alcohol and coffee consumption, smoking, length of work, symptoms (Euroquest) and results of Block Design test. Afterward, all workers were repeatedly examined (on Monday and Friday of a working week, before and after workshift) for stress and arousal (Mood Scale) and complex reaction times (Color Word Vigilance, CWV), the latter being the outcome. Individual exposure was assessed through urinary end-shift concentrations of nitrous oxide (N(2)O) and isoflurane. According to the highest value of urinary excretion of N(2)O in the week, exposed workers were subdivided in three groups ( or =13 and or = 27 microg/l). The values of 13 and 27 microg/l correspond to environmental concentrations of 25 and 50 ppm, respectively. In order to take into account the pre-existing abilities of exposed and reference workers, and investigate the neurobehavioral changes over time, longitudinal data were analyzed by a two-stage regression model and analysis of variance for repeated measures (MANOVA). The former method, controlling for confounding factors and Monday morning CWV (which conveyed the pre-existing ability of the subjects), showed that, with respect to unexposed nurses, reaction times were significantly (p or = 27 microg/l. Therefore, at MANOVA, all subjects were categorized in two classes (N(2)O urinary concentrations or = 27 microg/l), and CWV results were adjusted for the confounding variables and effects of stress and arousal, taken concurrently with CWV. CWV significantly (p 27 microg/l
Le patologie del personale ospedaliero
No full textAbstract
Occupational diseases and labour accidents in health care workers (Azienda Ospedaliera di Padova) were evaluated from 1990 to 2000; the information collected is compared with the same data of Regione Veneto and INAIL. 262 occupational diseases were found; nurses are more affected than other health care workers. In both reports (Azienda Ospedaliera di Padova and Osservatorio epidemiologico della Regione Veneto) half of the occupational diseases and injuries are represented by allergic disease. Low back pain is also equally represented in Azienda Ospedaliera and in Osservatorio epidemiologico results (5.3% and 6.6% respectively). Among the labour accidents reported to INAIL from 1994 to 2000, 25% of them were represented by falls and slips, 23% by car accidents, 17% were caused by tools, 17% by movement of goods and persons, 8% by contact with splinters, liquids, dusts, 5% by assaults and 5% by contact with blood or body fluid. The latter result is widely underestimated in the INAIL report, because these events usually produce a temporary inability of less than 3 days; in fact, they represent more than half of the labour accidents treated at the Azienda Ospedaliera di Padova. Medical surveillance (in exposure to aldehydes, anaesthetic gases, chemioterapic drugs) has shown many other occupational health problems that often need specific structural intervention (restructuration and restoration of workplaces in health care environments), and work organization changes
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