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Validation of a numerical model for the mechanical behavior of a continuous positive airway pressure mask
Full text linkFinite Element models (FEM) are developed for the analysis of the contact pressures exerted by a Continuous Positive Airway Pressure (CPAP) mask applied to a dummy head. This is seen as a preliminary step in the analysis of the mechanical effects of CPAP masks applied to human faces, such as recently employed for the care of COVID-19 patients, or other purposes. These mechanical effects can range from negligible, in the case of correct positioning, sufficiently light tension in the headgear, correct mask design, etc., to the possible development of device-related pressure ulcers and/or dentofacial deformations, especially in children. The results of Finite Element analyses are compared, for their validation, with experimental ones. The numerical analysis tool appears able to predict, at an acceptable cost, both the intensity and the area distribution of the contact pressures, as well as the force-displacement relationship occurring in the headgear. This might help the design and the production of more effective and tolerable CPAP masks
Stress-like effects of intermittent exposures to a strong magnetic field in weanling mice
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Primary headaches: reduced circulating beta-lipotropin and beta-endorphin levels with impaired reactivity to acupuncture.
No full textEleven patients affected by common migraine (CM), eleven affected by daily chronic headache (DCH), and eight healthy volunteers were studied. Plasma levels of beta-endorphin (beta EP), beta-lipotropin (beta LPH). ACTH and cortisol were measured in basal conditions and after traditional Chinese acupuncture (TCA). Basal beta LPH and beta EP plasma levels (pg/ml) in the DCH patients (57.6 +/- 9.5 and 16.8 +/- 2.5, respectively; M +/- SE) were lower than those found in the controls (83.6 +/- 13.7 and 26.0 +/- 6.1; p less than 0.001), while those found in the CM cases showed inter-mediate values (75.3 +/- 12.0 and 24.4 +/- 5.8). ACTH and cortisol concentrations in both the CM and DCH patients were in the same range as those of the control group. TCA caused an increase in beta LPH and beta EP plasma concentrations in the control group (beta LPH: 117 +/- 16.9; beta EP: 44.1 +/- 6.7). Opioid plasma levels, however, remained unmodified after TCA in both the CM and DCH groups. ACTH plasma levels remained stable after TCA in all three subject groups. Patients suffering from primary headache are characterized by low beta LPH and beta EP plasma levels and by a poor reactivity of circulating opioids to non-stressful stimuli
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