1,721,345 research outputs found
Bridging gaps in migrant health competencies for infectious and tropical diseases specialists: the experience of the University of Bari from Lampedusa to Apulian Ghettos
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Direct-Acting Antiviral-Induced Hepatitis C Virus Clearance and Herpesvirus Reactivation: A Double Face of Janus?
No full textDAA-induced HCV clearance and herpesvirus reactivatio
Patient-centred approaches for drug-resistant tuberculosis
No full textTwo crucial aspects deserve further attention: (1) the importance of integrated care models that go beyond pharmacological treatment; and (2) the need for tailored strategies targeting socially and structurally vulnerable groups, especially migrants and those with severe social disadvantages
Direct-acting antivirals for HIV/HCV co-infected individuals: as good as it gets?
No full textAlthough HIV/HCV co-infected individuals were historically considered a "difficult to treat" population in the era of Interferon (IFN)-based anti-HCV treatment, the introduction of direct-acting antivirals, characterized by excellent efficacy and good safety profile, has widely revolutionized the HCV treatment scenario. Recent real life studies reported excellent sustained virological response rates in HIV/HCV co-infected subjects, thus confirming data obtained in randomized clinical trials. However, certain issues have recently emerged in this population. In fact, high rates of acute HCV infection and reinfections were documented in several studies, particularly in HIV-positive men who have sex with men. Moreover, drug-drug interactions with ART or other co-medications may require careful considerations as well as the management of HIV/HCV co-infected subjects with chronic kidney disease and advanced liver disease in the course of a DAA-based treatment. Hence, we aim to review DAA efficacy studies performed in HIV/HCV co-infected patients in both randomized clinical trials and real-world cohorts. In addition, current challenges and future perspectives are discussed in order to optimize management strategies for HIV/HCV co-infected subjects and their access to care in clinical practice
Epidemiological multicentric Italian society of infectious and tropical diseases study on prevalence of tropical diseases in hospitalized immigrants in Italy during 2002
No full textHepatic encephalopathy in the course of anti-HCV therapy with paritaprevir/ritonavir, ombitasvir, dasabuvir and ribavirin
No full textHCV and diabetes: towards a ‘sustained’ glycaemic improvement after treatment
with DAA
Epidemiological multicentric Italian society of infectious and tropical diseases study on prevalence of tropical diseases in hospitalized immigrants in Italy during 2002
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