1,721,019 research outputs found
[Studies on cardiac metastases. II. Disturbances of atrioventricular conduction due to neoplastic cause]
No full textIn vitro stimulation of apparent intestinal alkaline phosphatase activity by thyrocalcitonin
No full textThrombocytopenic purpura during therapy with simvastatin
No full textThe authors describe a case of very serious thrombocytopenic purpura occurring in a diabetic and hyperlipidemic woman during therapy with simvastatin, an HMG-CoA reductase inhibitor drug. Interruption of the medical treatment produced a prompt reversal of the thrombocytic attack: one year later the patient's platelet count remains within the normal range. The authors have not found other reports in the medical literature of similar serious reactions during therapy with an HMG-CoA reductase inhibiting substance; nevertheless, a causal nexus is hypothesized but not argued in this case, since further studies will be needed before this connection can be established
Certain specific functional responses of human neutrophil exhibit different dose-dependence on formyl peptides
No full textAnalysis of dose-dependence curves provides biology and pharmacology with information on the mechanisms by which cells and organisms respond to specific agonists/antagonists. a series of studies were done to evaluate the sensitivity of human neutrophils to the peptide fMLP taking into consideration several distinct functional responses to these leukocytes
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