79 research outputs found
On the morphological characterization of the Auxiliary verb RAMU and its related issues
No full text1 はじめに 2 考察の基點となる形態論上の諸槪念について 3 「助動詞ラム」の形態論的位置づけ 4 3章の議論から派生して得られる見解 5 終はりにThe author is going to discuss on morphological and phonological properties of, in traditional Japanese study KOKUGOGAKU, so-called auxiliary verb RAMU and related some linguistic issues --especially verb’s that-- of Classical Japanese in this paper. In previous studies, this form, for instance KOKUGOGAKU, is thought as one of Auxiliary verb, but the other hand, this form was thought as inflectional clitic (for example Ooki(2010)) and so on. Against these previous studies, the author argues that this RAMU is inflection suffixes based on following 6 reasons. (1)All these, are so-called RAMU’s “word forms” in KOKUGOGAKU, are able to appear alone. (2)All these appear with words belonging to specific “part of speech”. (3)”Verbs” always ending with [u]. (4)All these do not require specific “Word form”. (5)RAMU itself has only specific “Word forms”. (6)All these appear in a final positon of continuous forms. And, the author suggests it is fair that the underlying forms of this RAMU are //urramu//, //urrame// in Classical Japanese of Kyoto dialect, Hei’an era, from very rare cases which these surface form are [urura…]. And so, By seeing records of Sho-ten materials, these reflect prosody –especially word that--, the author argues that it shows that this RAMU are suffixes making a phonological independent domain. In addition, the author suggests following points as matters related to RAMU. (1)The accent of verb is in root, not in suffixes, Underlyingly. (2)Underlying form of the so-called Auxiliary verb RASI is //urrasi//, too
「助動詞ラム」をめぐつて : その形態論的位置づけと關連する問題
No full textThe author is going to discuss on morphological and phonological properties of, in traditional Japanese study KOKUGOGAKU, so-called auxiliary verb RAMU and related some linguistic issues --especially verb’s that-- of Classical Japanese in this paper. In previous studies, this form, for instance KOKUGOGAKU, is thought as one of Auxiliary verb, but the other hand, this form was thought as inflectional clitic (for example Ooki(2010)) and so on. Against these previous studies, the author argues that this RAMU is inflection suffixes based on following 6 reasons. (1)All these, are so-called RAMU’s “word forms” in KOKUGOGAKU, are able to appear alone. (2)All these appear with words belonging to specific “part of speech”. (3)”Verbs” always ending with [u]. (4)All these do not require specific “Word form”. (5)RAMU itself has only specific “Word forms”. (6)All these appear in a final positon of continuous forms. And, the author suggests it is fair that the underlying forms of this RAMU are //urramu//, //urrame// in Classical Japanese of Kyoto dialect, Hei’an era, from very rare cases which these surface form are [urura…]. And so, By seeing records of Sho-ten materials, these reflect prosody –especially word that--, the author argues that it shows that this RAMU are suffixes making a phonological independent domain. In addition, the author suggests following points as matters related to RAMU. (1)The accent of verb is in root, not in suffixes, Underlyingly. (2)Underlying form of the so-called Auxiliary verb RASI is //urrasi//, too.1 はじめに 2 考察の基點となる形態論上の諸槪念について 3 「助動詞ラム」の形態論的位置づけ 4 3章の議論から派生して得られる見解 5 終はり
Emerging Role of Biopharmaceutical Classification and Biopharmaceutical Drug Disposition System in Dosage form Development: A Systematic Review
Get PDFBiopharmaceutical classification system (BCS) is an advanced tool used for classifying medicines based on dissolution, water solubility, and intestinal permeability, which affect the absorption of active pharmaceutical ingredients (API) from immediate-release solid oral forms. It is useful to the formulation researchers to develop novel dosage forms based on modernistic rather than experimental approaches. The current review focuses on the fundamentals, objectives, guidance of BCS, characteristics of BCS drugs, their importance and applications of BCS. This review explains the challenges in drug development in terms of solubility and in vivo disposition. In the current review, new strategies for improving BCS II drug solubility as well as biopharmaceutical drug disposition properties which are utilized throughout the early stages of drug development and commercialization are mainly discussed
Several men by a fence near Government House
No full textTitle imposed. Caption on the rear of the photograph: “Kanakas at Atemble. Outside Government house.” Captions reflect the attitudes of the author at the time they were written, and do not reflect the values of the archives. These photographs were taken during Stinear's time in Papua New Guinea from 1936-1937, in the Sepik, Ramu, and Gulf regions
Two men near Atemble
No full textTitle imposed. Caption on the rear of the photograph: “Kanakas at Atemble”. Captions reflect the attitudes of the author at the time they were written, and do not reflect the values of the archives. These photographs were taken during Stinear's time in Papua New Guinea from 1936-1937, in the Sepik, Ramu, and Gulf regions
Development and Validation of Analytical Method for Estimation of Balofloxacin in Bulk and Pharmaceutical Dosage Form by RP-HPLC
Get PDFThe objective of the present study is to develop simple, accurate, sensitive and economic method for effective quantitative determination of Balofloxacin in active pharmaceutical ingredient. as well as in Pharmaceutical dosage forms by using HPLC. The newly developed method is validated in accordance with the analytical parameters for quantitative estimation of Balofloxacin in pharmaceutical dosage forms as per ICH guidelines. The method was validated for parameters like accuracy, linearity, precision, specificity, ruggedness, robustness, and system suitability. The detection was carried out using UV detector at 249 nm. The solutions were injected at a constant flow rate of 1 ml/min. the linearity range of Balofloxacin was found to be 10-60 g/ml. The values of % RSD are less than 2% indicating accuracy and precision of the method. The percentage recovery varies from 98-102% of Balofloxacin. LOD were found to be 0.210 µg/ml and LOQ found to be 0.637µg/ml for Balofloxacin. The results obtained on the validation parameters met ICH guidelines; it inferred the method found to be simple, accurate, precise and linear. The method was found to be having suitable application in routine laboratory analysis with high degree of accuracy and precision
Design and testing of a thick-film dual-modality sensor for composition measurements in heterogeneous mixtures
No full textThe current paper focuses on design and laboratory evaluation of a dual-modality sensor, developed for the needs of oil and gas extraction industry to measure the composition of heterogeneous mixtures in harsh conditions. The sensor combines ultrasonic and electrical measurement techniques, which are non-destructive, rapid and can potentially provide an on-line industrial measurement. Such a ‘dual-modality’ measurement could potentially be reliable in a wider range of process conditions. A distinct feature of the sensors presented here is their construction, which makes use of the thick-film technology, enabling the construction of multi-layered structures of both conductive and non-conductive layers, some of which may exhibit piezoelectric properties for ultrasonic measurement purposes. These are later fired on a ceramic substrate to provide rugged sensors, capable of working in aggressive industrial environments. Laboratory experiments to investigate the feasibility of the dual-modality sensors were conducted and some comparisons with the theoretical predictions are presented
A trading scene around Government house, Atemble. Our 55 boys have just been "signed up" by Assist District Officer Reid - in white - and Patrol Officer Wright
No full textCaptions on the rear of the photographs are displayed as the title. Captions reflect the attitudes of the author at the time they were written, and do not reflect the values of the archives. Stinear occasionally notes weather conditions and brightness when taking photographs. These photographs were taken during Stinear's time in Papua New Guinea from 1936-1937, in the Sepik, Ramu, and Gulf regions
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