180,876 research outputs found
M&A e privte equity. Dinamiche, przzi e performance nei mercati internazionali. Primo Rapporto Annuale.
No full textIl volume rappresenta un contributo operativo di conoscenza dell'attività professionale dell' M&A e del private equity nel nostro paese, in Europa e nei principali mercati finanziari. L'obiettivo è di analizzae l'andamento e le principali caratteristiche dele operazioni di finanza straordinaria, allo scopo di evidenziare gli aspetti critici di successo per gli studiosi e gli operatori del settore
Scale-free percolation mixing time
No full textAssign to each vertex of the one-dimensional torus i.i.d. weights with a heavy-tail of index τ−1>0. Connect then each couple of vertices with probability roughly proportional to the product of their weights and that decays polynomially with exponent α>0 in their distance. The resulting graph is called scale-free percolation. The goal of this work is to study the mixing time of the simple random walk on this structure. We depict a rich phase diagram in α and τ. In particular we prove that the presence of hubs can speed up the mixing of the chain. We use different techniques for each phase, the most interesting of which is a bootstrap procedure to reduce the model from a phase where the degrees have bounded averages to a setting with unbounded averages.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Applied Probabilit
Corrigendum: Salvi D, Al-Kandari M, Oliver PG, Berrilli E, Garzia M (2022) Cryptic marine diversity in the northern Arabian Gulf: an integrative approach uncovers a new species of oyster (Bivalvia: Ostreidae), Ostrea oleomargarita. Journal of Zoological Systematics and Evolutionary Research 2022: 7058975. https://doi.org/10.1155/2022/7058975
No full textHere we provide a Code-compliant description of Ostrea oleomargarita Oliver, Salvi, and Al-Kandari, sp. nov as reported in Salvi et al. (2022) and complemented with the ZooBank registration numbers of the publication and of the new species name. Results of phylogenetic, species delimitation, and morphological analyses on which the systematic assessment of this new species is based can be found in Salvi et al. (2022)
RENFAST algorithm dataset
No full textThis repository contains the image dataset and the manual annotations used in the following work:
Salvi M., Mogetta A., Meiburger K. M., Gambella A., Molinaro L., Barreca A., Papotti M., and Molinari F., "Karpinski Score under digital investigation: a fully automated segmentation algorithm to identify vascular and stromal injury of donors’ kidneys", Electronics 2020
ABSTRACT
In kidney transplantations, the evaluation of the vascular structures and stromal areas is crucial for determining kidney acceptance, which is currently based on the pathologist’s visual evaluation. In this context, an accurate assessment of the vascular and stromal injury is fundamental to assessing the nephron status. In the present paper, the authors present a fully automated algorithm, called RENFAST (Rapid EvaluatioN of Fibrosis And vesselS Thickness), for the segmentation of kidney blood vessels and fibrosis in histopathological images. The proposed method employs a novel strategy based on deep learning to accurately segment blood vessels, while interstitial fibrosis is assessed using an adaptive stain separation method. The RENFAST algorithm is developed and tested on 350 periodic acid–Schiff (PAS) images for blood vessel segmentation and on 300 Massone’s trichrome (TRIC) stained images for the detection of renal fibrosis. In the TEST set, the algorithm exhibits excellent segmentation performance in both blood vessels (accuracy: 0.8936) and fibrosis (accuracy: 0.9227) and outperforms all the compared methods. To the best of our knowledge, the RENFAST algorithm is the first fully automated method capable of detecting both blood vessels and fibrosis in digital histological images. Being very fast (average computational time 2.91 s), this algorithm paves the way for automated, quantitative, and real-time kidney graft assessments
SCAN algorithm dataset
No full textThis repository contains the image dataset and the manual annotations used in the following work:- Salvi M., Michielli N., and Molinari F., "Stain Color Adaptive Normalization (SCAN): separation and standardization of histological stains in digital pathology", Computer Methods and Programs in Biomedicine 2020 (DOI: 10.1016/j.cmpb.2020.105506)ABSTRACTThe diagnosis of histopathological images is based on the visual analysis of tissue slices under a light microscope. However, the histological tissue appearance may assume different color intensities depending on the staining process, operator ability and scanner specifications. This stain variability affects the diagnosis of the pathologist and decreases the accuracy of computer-aided diagnosis systems. In this context, the stain normalization process has proved to be a powerful tool to cope with this issue, allowing to standardize the stain color appearance of a source image respect to a reference image.In this paper, novel fully automated stain separation and normalization approaches for hematoxylin and eosin stained histological slides are presented. The proposed algorithm, named SCAN (Stain Color Adaptive Normalization), is based on segmentation and clustering strategies for cellular structures detection. The SCAN algorithm is able to improve the contrast between histological tissue and background and preserve local structures without changing the color of the lumen and the background.Both stain separation and normalization techniques were qualitatively and quantitively validated on a multi-tissue and multiscale dataset, with highly satisfactory results, outperforming the state-of-the-art approaches. SCAN was also tested on whole-slide images with high performances and low computational times.The potential contribution of the proposed standardization approach is twofold: the improvement of visual diagnosis in digital histopathology and the development of powerful pre-processing strategies to automated classification techniques for cancer detection
FAST algorithm dataset
No full textThis repository contains the FAST algorithm graphical user interface and some sample image used in the following work:- Salvi M., Cerrato V., Buffo A., and Molinari F., "Automated Segmentation of Brain Cells for Clonal Analyses in Fluorescence Microscopy Images", J Neurosci Methods 2019 (DOI: 10.1016/j.jneumeth.2019.108348)ABSTRACTThe understanding of how cell diversity within and across distinct brain regions is ontogenetically achieved is a pivotal topic in neuroscience. Clonal analyses based on multicolor cell labeling represent a powerful tool to tackle this issue and disclose lineage relationships, but produce enormous sets of fluorescence images, leading to time consuming analyses that may be biased by the operator’s subjectivity. Thus, time-efficient automated software are needed to analyze images easily, accurately and without subjective bias.In this paper, we present a fully automated method, named FAST (‘Fluorescent cell Analysis Segmentation Tool’), for the segmentation of neural cells labeled by multicolor combinations of fluorophores and for their classification into clones. The proposed method was tested on 77 high-magnification fluorescence images of adult mouse cerebellar tissues acquired using a confocal microscope. Automatic results were compared with manual annotations and two open-source software designed for cell detection in microscopic imaging. The algorithm showed very good performance in the cellular detection and in the assignment of the clonal identity.To the best of our knowledge, FAST is the first fully automated technique for the analysis of cellular clones based on combinatorial expression of fluorescent proteins. The proposed approach allows to perform clonal analyses easily, accurately and objectively, overcoming those biases and errors that may result from manual annotations. Moreover, it can be broadly applied to the quantification and colocalization within cells of fluorescent markers, therefore representing a versatile and powerful tool for automated quantitative analyses in fluorescence microscopy
Discurs del rector de la Universitat de Girona, Dr. Joaquim Salvi, en l’acte d’investidura com a doctor honoris causa de Josep Maria Casasús
No full textDiscurs del rector de la Universitat de Girona, Dr. Joquim Salvi, en l’acte d’investidura com a doctor honoris causa de Joaep M. Casasús. Josep M. Casasús va rebre el títol de Doctor honoris causa de la UdG per la seva trajectòria com a periodista i la seva prestigiosa activitat acadèmica. Per l’excel·lència i extensió de la seva recerca i el seu protagonisme en la recuperació del periodisme històric català, i pel seu incondicional suport en la construcció de l’àmbit de Comunicació de la Ud
Exploring political and banking language for institutional purposes
No full textThis contribution aims to identify the features and explore the potential strength of English in the construal of institutional discourse with reference to the topic of economic crisis. For this analysis the speeches of two outstanding figures are considered, delivered in the period between June and September 2011: Josè Manuel Barroso, the President of the European Commission, and Mario Draghi in his triple role as the Governor of the Bank of Italy, the President of the Financial Stability Board and a candidate to the presidency of the ECB. Given the specific topic and period, the documents are characterized by a homogeneous content and a similar mixed genre, as they were delivered orally based on a written draft, then divulged on websites. The documents have been processed in two sub-corpora which are comparable according to topic, size and supra-national audience. This contribution has three objectives. First of all, to confirm the importance of small and sample corpora (Sinclair 1991, Stubbs 1996) for the analysis of specialized language, particularly in the case of documents where language expresses contents strongly influenced by economic principles, as well as by social and political instances. Second, to detect similarities and differences within the wide territory of institutional language: the sender’s identity and his institutional position affect the macro-structure and the speech organization in relation to the relevant aims and the connected arguments (Benwell and Stokoe 2010). Finally, to integrate the quantitative analysis of the corpora, which allows us to closely observe aspects of keyness and aboutness (Bondi and Scott eds. 2010), with a qualitative discourse analysis so that the construction of messages can be investigated at multiple levels of textual organization (Salvi 2001a). In the present research quantitative analysis aims to prove the assumption that a prevalence of political and economic/banking language characterizes Barroso’s and Draghi’s speeches respectively; furthermore, discourse analysis helps to show the high level of valutative language in the two sub-corpora and the speakers’ position in the specific context of the crisis in both a local and a global perspective (Hunston and Thomson 2000). As already discussed in an analysis of academic lectures in the field of economics (Salvi 2011b), the comparison between corpora (Biber et al. 1998), although of a small size, shows particular pragmatic aspects which reflect identities, ideology and social relationships developed in context
Fusioni e acquisizioni
No full textAnalisi dei benefici delle operazioni di acquisizione; modalita' di passaggio dal valore al prezzo e fattori principali che influiscono sul prezzo di acquisizione; negoziazioni comparabili e metodologie di calcolo dei moltiplicatori; il mercato dell'acquisizione in Italia
Diversità genetica, filogenesi e biogeografia di Micrabris (Coleoptera, Meloidae) in penisole mediterranee
No full textIn accordo con ipotesi biogeografiche condivise, le penisole mediterranee hanno rappresentato centri di rifugio dei Biota europei nel Pleistocene. Taxa isolati in zone montane sudeuropee possono essersi differenziati durante periodi interglaciali pleistocenici, ma anche in periodi precedenti. In questo studio vogliamo verificare queste ipotesi su un gruppo di specie di Mylabris del sottogenere Micrabris (Meloidae), perlopiù legate ad aree montane o steppiche continentali, spesso con popolazioni isolate, ma alcune anche di quote inferiori. La maggiore diversità di Micrabris in Europa si riscontra nella penisola iberica, con 9 specie (M. beauregardi, M. deferreri, M. dejeani, M .flexuosa, M. maculosopunctata, M. nevadensis, M. platai, M. sobrina, M. varians). Nell’Italia peninsulare vi sono 3 specie (M. flexuosa, M. obsoleta, M. pusilla), con un’elevata diversità intraspecifica evidenziata da indagini su allozimi e mtDNA. Nel nostro studio sono analizzati dati del gene mitocondriale COI in popolazioni di tutte le specie iberiche e italiane con i seguenti obiettivi: 1) determinare il grado di differenziamento genetico tra le specie e testare l’ipotesi di monofilia reciproca tra il popolamento delle due penisole mediante un’analisi filogenetica preliminare; 2) analizzare la storia biogeografica delle specie e delle popolazioni per comprendere se è applicabile a questo gruppo un’ipotesi di speciazione pleistocenica; 3) comparare i livelli di differenziamento mitocondriale nelle specie delle due penisole. Le analisi filogenetiche non supportano l’esistenza di monofilia reciproca tra le due penisole, suggerendo un’antica origine comune pre-pleistocenica dei popolamenti, forse da antenati turano-anatolici. La differenziazione varia molto tra i gruppi: le specie montane (M. flexuosa, M. pusilla, M. nevadensis, M. sobrina) sono ben distinte geneticamente e morfologicamente, mentre le differenze genetiche all’interno di quelle iberiche di bassa quota non sono nette. In particolare M. maculosopunctata e M. beauregardi, sebbene distinte morfologicamente, mostrano parafilia e introgressione in zone est iberiche. Al contrario, nella penisola italiana il differenziamento genetico corrisponde bene a quello morfologico. La distribuzione longitudinale dei sistemi montani italiani può aver favorito la dispersione verso sud delle specie montane e l’interscambio genetico tra popolazioni, ostacolando la formazione di specie, mentre nella penisola iberica la disposizione trasversale predominante delle catene montuose ha favorito un differenziamento tassonomico veloce per isolamento durante i periodi glaciali
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