75,144 research outputs found
Modelling and results of double-diffusive convection for microgravity vapour growth in vertical ampoules
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Marangoni convection in a liquid layer overlying a porous layer with evaporation at the free surface
No full text3D numerical simulations of thermodiffusion experiment for a ternary mixture on-board Foton
No full textMarangoni convection in a liquid layer overlying a porous layer with evaporation at the free surface
No full textThree-dimensional modelling of GeSi growth in presence of axial and rotating magnetic fields
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Experiments and Modeling of Te Segregation in Te-Doped GaSb in Terrestrial and Microgravity Conditions Using the Bridgman Technique
No full textOutcome of breast cancer patients treated outside of clinical trials
No full textBackground: Information on outcome of breast cancer patients treated in the community is scarce. Data on outcome of patients treated in real-life clinical practice may provide useful information for performance improvement. Methods: Study population is from a single institution practice at the American University of Beirut Medical Center. Demographics, clinical characteristics and survival data on patients diagnosed 1997-2010 in two IRB-approved studies were entered and analyzed on SPSS program. Survival was estimated using Kaplan Meier Method. Findings: Total was 519 patients. 23.9percent had stage I, 39.7percent stage II, 30.4percent Stage III and 6percent stage IV. ER positive in 74.4percent of patients. 30.6percent of patients 35 had TNBC compared to 12.3percent for the whole group. 45.9percent of non-metastatic patients had breast-conserving therapy (BCT). BCT rates increased to 64percent during the second half of the study, coinciding with increasing awareness and changing cultural mores. 5-year and 10-year overall survivals for stage I were 98.9percent and 80.5percent, 89.2percent and 70.7percent for stage II, 67.6percent and 35.5percent for stage III, and 39.1percent and 26.1percent for stage IV respectively. Interpretation: Patients treated outside clinical trials in a multidisciplinary fashion according to guidelines have comparable, and at times better, survival compared to data from trials or population statistics. Locally generated outcome data could be valuable for evaluating results of treatment at individual practices for the purpose of quality assessment and improvement. Our data also provides report of increased rate of breast conserving surgery from Middle East. © Ivyspring International Publisher.Adib Salim M, 2009, J Med Liban, V57, P72; Adib S M, 2009, East Mediterr Health J, V15, P6; Alameddine R, 2013, J CAN RES UPDATES, V2; Anderson BO, 2011, LANCET ONCOL, V12, P387, DOI 10.1016-S1470-2045(11)70031-6; Assi HA, 2013, J THORAC DIS, V5, pS2, DOI 10.3978-j.issn.2072-1439.2013.05.24; Chopra R, 2001, J CLIN ONCOL, V19, p106S; El Saghir NS, 2011, BREAST S2, V20, P3, DOI DOI 10.1016-J.BREAST.2011.02.006; El Saghir NS, 2008, CANCER-AM CANCER SOC, V113, P2315, DOI 10.1002-cncr.23836; El Saghir Nagi S, 2007, Int J Surg, V5, P225, DOI 10.1016-j.ijsu.2006.06.015; El Saghir NS, 2006, BMC CANCER, V6, DOI 10.1186-1471-2407-6-194; El Saghir NS, 2012, LANCET ONCOL, V13, P1076, DOI 10.1016-S1470-2045(12)70479-5; El Saghir NS, 2005, ETHNIC DIS, V15, P11; El Saghir NS, 2012, BREAST, V21, P423, DOI 10.1016-j.breast.2012.06.007; Ferlay J, 2010, INT J CANCER, V127, P2893, DOI 10.1002-ijc.25516; Gianni L, 2011, LANCET ONCOL, V12, P236, DOI 10.1016-S1470-2045(11)70033-X; Hammond MEH, 2010, J CLIN ONCOL, V28, P2784, DOI 10.1200-JCO.2009.25.6529; Harford JB, 2011, BREAST, V20, pS20, DOI 10.1016-j.breast.2011.02.007; Hernandez-Aya LF, 2011, J CLIN ONCOL, V29, P2628, DOI 10.1200-JCO.2010.32.1877; Holm T, 1997, BRIT J SURG, V84, P657, DOI 10.1002-bjs.1800840520; Krag DN, 2010, LANCET ONCOL, V11, P927, DOI 10.1016-S1470-2045(10)70207-2; Lee LJ, 2011, CANCER-AM CANCER SOC, V117, P3093, DOI 10.1002-cncr.25911; Mackey JR, 2012, LANCET ONCOL, V14, P72; Najjar H, 2010, INT J SURG, V8, P448, DOI 10.1016-j.ijsu.2010.05.012; National Cancer Institute, SEER CANC STAT REV 1; National Cancer Registry, 2003, CANC LEB 2003; Albain K, 2012, LANCET, V379, P432, DOI 10.1016-S0140-6736(11)61625-5; Piccart-Gebhart MJ, 2005, NEW ENGL J MED, V353, P1659, DOI 10.1056-NEJMoa052306; El Saghir Nagi S, 2002, J Med Liban, V50, P3; Romond EH, 2005, NEW ENGL J MED, V353, P1673, DOI 10.1056-NEJMoa052122; Wolff AC, 2007, ARCH PATHOL LAB MED, V131, P18, DOI 10.1043-1543-2165(2007)131[18:ASOCCO]2.0.CO;21
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