2 research outputs found
Ultrafine particles (UFPs) from domestic wood stoves: genotoxicity in human lung carcinoma A549 cells
No full textIn this paper, results on the potential toxicity of ultrafine particles (UFPs d < 100 nm) emitted by the combustion of logwood and pellet (hardwood and softwood) are reported. The data were collected during the TOBICUP (TOxicity of BIomass COmbustion generated Ultrafine Particles) project, carried out by a team composed of interdisciplinary research groups. The genotoxic evaluation was performed on A549 cells (human lung carcinomacells) using UFPs whose chemical composition was assessed by a suite of analytical techniques. Comet assay and γ-H2AX evaluation show a significant DNA damage after 24 h treatment. The interpretation of the results is based on the correlation among toxicological results, chemical-physical properties of UFPs, and the type and efficiency conditions in residential pellet or logwood stoves
Sources, characteristics, toxicity, and control of ultrafine particles: an overview
No full textAir pollution by particulate matter (PM) is one of the main threats to human health, particularly in large cities where pollution levels are continually exceeded. According to their source of emission, geography, and local meteorology, the pollutant particles vary in size and composition. These particles are conditioned to the aerodynamic diameter and thus classified as coarse (2.5–10 μm), fine (0.1–2.5 μm), and ultrafine (<0.1 μm), where the degree of toxicity becomes greater for smaller particles. These particles can get into the lungs and translocate into vital organs due to their size, causing significant human health consequences. Besides, PM pollutants have been linked to respiratory conditions, genotoxic, mutagenic, and carcinogenic activity in human beings. This
paper presents an overview of emission sources, physicochemical characteristics, collection and measurement methodologies, toxicity, and existing control mechanisms for ultrafine particles (UFPs) in the last fifteen years.Moreno-Ríos, Andrea L.Tejeda-Benitez, Lesly-will be generated-orcid-0000-0003-3240-917X-600Bustillo Lecompte, Ciro Fernando-will be generated-orcid-0000-0001-5262-7743-60
