995 research outputs found
Optimum Currency Areas Structural Changes and the Endogeneity of the OCA Criteria: Evidence from Six New EU Member States
No full textThe present paper has two aims. The first aim is to test whether six new member states of the European Union (the six Central and Eastern European Countries) form an optimum currency area (OCA) with the eurozone, in an attempt to assess their readiness for euro adoption. The second aim is to examine whether the introduction of the euro in 1999 and the decision of the countries to seek to join the euro area created any forces fostering their convergence, evidence which would be in line with the theory on the endogeneity of the OCA criteria. Our findings indicate that the introduction of the euro did promote integration of the six new member states and that, at present, they are quite well aligned with the eurozone.EU enlargement; OCA; real exchange rates; cointegration; GPPP.
Balanced Ero1 activation and inactivation establishes ER redox homeostasis
No full textThe endoplasmic reticulum (ER) provides an environment optimized for oxidative protein folding through the action of Ero1p, which generates disulfide bonds, and Pdi1p, which receives disulfide bonds from Ero1p and transfers them to substrate proteins. Feedback regulation of Ero1p through reduction and oxidation of regulatory bonds within Ero1p is essential for maintaining the proper redox balance in the ER. In this paper, we show that Pdi1p is the key regulator of Ero1p activity. Reduced Pdi1p resulted in the activation of Ero1p by direct reduction of Ero1p regulatory bonds. Conversely, upon depletion of thiol substrates and accumulation of oxidized Pdi1p, Ero1p was inactivated by both autonomous oxidation and Pdi1p-mediated oxidation of Ero1p regulatory bonds. Pdi1p responded to the availability of free thiols and the relative levels of reduced and oxidized glutathione in the ER to control Ero1p activity and ensure that cells generate the minimum number of disulfide bonds needed for efficient oxidative protein folding.National Institutes of Health (U.S.) (GM46941
Foreign Exchange Intervention and Equilibrium Real Exchange Rates
No full textMonetary authorities intervene in the currency markets in order to pursue a monetary rule and/or to smooth exchange rate volatility caused by speculative attacks. In the present paper we investigate for possible intervention effects on the volatility of nominal exchange rates and the estimated equilibrium behaviour of real exchange rates. The main argument of the paper is that omission of intervention effects -when they are significant- would bias the ability to detect any PPP-based behaviour of the real exchange rates in the long run. Positive evidence for this argument comes from the experience of six Central and Eastern European economies, whose exchange markets are characterised by frequent interventions.Foreign Exchange Market Intervention; Real Exchange Rates; PPP.
Implementación de indicadores de gestión de proyectos de costos y tiempo en la empresa Sideris S. A. C.
No full textEl presente trabajo se realizó con objetivo de implementar indicadores de gestión de proyectos en la empresa SIDERIS SAC, aplicando mis conocimientos adquiridos en mi formación en Ingeniería Industrial y mi propia experiencia laboral en la gestión de proyectos.
Se elaboró un diagnóstico situacional de la empresa, se empleó el flujograma de procesos del área de proyectos, asimismo se realizó un levantamiento de información en base a cinco proyectos más representativos realizados entre 2020 al 2023, y por último se usó el diagrama de causa y efecto, con estas herramientas se evidencio una deficiente gestión en el área de proyectos, como resultado un promedio bajo en la productividad.
Con la ayuda de la guía del PMBOK, en su sexta edición, se propuso la implementación de indicadores gestión de costos y tiempo, aplicada en el caso de estudio, proyecto: “Implementación del sistema de Aire Acondicionado Mitsui - La Molina”, evidenciando un buen promedio de eficiencia, eficacia y productividad, asimismo mediante el uso de la técnica de valor ganado, se obtuvo un mejor índice en el rendimiento del costo (CPI) siendo 1.01 y del cronograma (SPI) con 0.98.
Al analizar el comparativo del antes y después del área de los proyectos se evidencia un aumento de productividad, pasando 81.07 % a 97.65%, esto significó un crecimiento de 16.58%, permitiendo tomar mejores decisiones en los futuros proyectos
Placing, displacing, replacing the sacred: science, religion, and spirituality
No full textIncludes bibliographical references (page 205).This is a reply to a target article in this issue by Lisa Sideris, "Science as Sacred Myth? Ecospirituality in the Anthropcene Age." Lisa Sideris is right on target, concerned about scientism. Big-history-epic-of-evolution accounts, such as Brian Swimme and Mary Evelyn Tucker in their Journey of the Universe direct us to awe, inviting us to see better what is going on at our local, personal scales by including microscales, ecosystemic, evolutionary, geological, and astronomical scales. Against local myths, a scientific account ("myth"?) can be definitive. Any contemporary culture must "incorporate" vast amounts of science. Journey of the Universe is an excellent video, though it would be better if it recognized that some native accounts are wrong
Testing for Long-Run PPP in a System Context: Evidence for the US, Germany and Japan
No full textThe present paper tests for the validity of long-run purchasing power parity (PPP) for the three key currencies of the recent floating exchange rate period, the US dollar, the German mark and the Japanese yen. The novelty of the paper is that the validity of the PPP conditions relating the economies of the US, Germany and Japan is tested in a system framework, which allows for possible interactions in the determination of the exchange rates and the prices of the three economies. Some form of causality among the variables of the system is also assessed empirically with the aid of weak exogeneity tests. The results illustrate the importance of the multilateral testing. Positive evidence for PPP is found: long-run PPP is supported for the US and Germany but also for the US and Japan, in contrast to evidence of earlier empirical studies. In addition, causality is found running from the US prices to the exchange rates and German and Japanese prices.Money demand; PPP, cointegration, causality
On human dignity and State sovereignty: The Italian Constitutional Court's 238/2014 judgment on State immunity for international crimes
No full textLame science? Blind religion?
No full textThis is an electronic version of an article published in Zygon®: Journal of Religion and Science.Includes bibliographical references.In Consecrating Science, Lisa Sideris argues that an anthropocentric and science-based cosmology encourages human arrogance and diminishes a sense of wonder in human experience immersed in the natural world, found in diverse cultural and religious traditions. I agree with her that science elevated to a commanding world view, scientism, is a common and contemporary mistake, to be deplored, a lame science. But I further argue that science has introduced us to the marvels of deep nature, and vastly increased our human appreciation of nature as a wonderland at levels great and small. Sideris is right to fear consecrating science. She—and the humanists, sages, and saviors—need also to fear blindness to what science has to teach us about cosmogenesis and wonderland Earth
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