3,446 research outputs found
Perkembangan Populasi Dan Sistim Pemeliharaan Kerbau Rakyat Di Lembah Napu Kabupaten Poso
Ferdiyanto Tarakolo. Perkembangan Populasi Dan Sistim Pemeliharaan Kerbau Rakyat Di Lembah Napu Kabupaten Poso (dibimbing oleh Kaharudin Kasim dan Padang Hamid). Penelitian ini bertujuan untuk : (1) mengetahui perkembangan populasi kerbau di Lembah Napu Kabupaten Poso, (2) mengetahui sistem pemeliharaan kerbau oleh peternak di Lembah Napu Kabupaten Poso. Penelitian ini dilakukan dengan menggunakan metode survey yang dilengkapi dengan daftar pertanyaan untuk melukiskan kondisi sebelumnya dan faktor yang ada sekarang berdasarkan fakta-fakta yang ada di lapangan. 1). Hasil penelitian menunjukkan bahwa rata-rata umur pejantan kawin pertama 32,31± 3,69 bulan (n=12), dan betina 42,30 ± 3,12 bulan (n=35), dengan lama bunting 11,45 ± 0,11 bulan (n=35), jarak kelahiran 16,55 ± 0,21 bulan (n=35), dan rata-rata frekuensi kawin perkebuntingan 1,75 ± 0,10 kali (n=35), 2) akibat pola pemeliharaan tradisional, maka populasi sangat rendah ditandai persentase kelahiran 28,57%/tahun (n=35) dengan tingkat kematian 13,51% atau bertambah sebanyak 32 ekor selama 3 tahun dengan rata-rata 10,67 ekor/tahun walaupun persentase penyapihan 80,00% (n=8). Peningkatan populasi kerbau hanya mampu bertambah sebanyak 0,34 ekor/tahun yang disebabkan oleh tingkat penjualan 10,33 ekor/tahun (n=24), 3) ternak kerbau di daerah penelitian masih tergolong usaha ternak tradisional dimana, teknik beternaknya masih bersifat sampingan. Cirinya penggembalaan kerbau dilepaskan dan diikat di lapangan/padang pengembalaan untuk memperoleh rumput dan hijauan lapangan. Kerbau tidak diberi makanan tambahan (konsentrat). Pemeliharaan kerbau dengan sistim ikat/pindah dilakukan oleh peternak dengan interval 1-3 kali/hari (n=24), dan 4) penyakit yang sering menyerang adalah ngorok, Cacing, Bloat dan Leher bengkak dengan pengobatan tradisional menggunakan ramuan-ramuan yang terdiri dari Acalypha indica L. (Akar kucing) untuk mengobati penyakit ngorok, Bischofia javanica Blume (Pepolo) untuk mengobati penyakit cacing, Breynia coronata Hook. F. (Teturu) untuk mengobati penyakit bloat, Euphorbia hirta L. (Katuli) untuk mengobati penyakit leher bengkak, Glochidion insigne Muell.(M.A.) J.J.S (Tambone/timbu) untuk mengobati penyakit cacing, dan Jatropha curcas L. (Tatanga) untuk mengobati penyakit leher bengkak dan bloat. Kata Kunci: Kerbau, Produktivitas, dan Manajemen
When an optimal control of hemostasis is fundamental: a case report of patient with simultaneous acquired FVIII deficiency and venous thromboembolism
Continuous infusion of rFVIII:a good choice for mild hemophiliac patient undergoing major oncologic surgery and reconstructive plastic surgery
Practical use of intermittent pneumatic compression as thromboprophylaxis in neurosurgery
Most patients undergoing neurosurgery are considered at increased risk for venous thromboembolism (VTE). Several studies have demonstrate that intracranial surgery, malignancy, leg weakness, prolonged procedures and advanced age can to increase VTE. Use of thromboprophylaxis is recommended to avoid this risk. Low molecular weight heparin (LMWH), low dose unfractionated heparin (LDUH), intermittent pneumatic compression (IPC) and graduated compression stocking (GCS) are commonly used as VTE prophylaxis. This article wants to show the practical use of IPC in neurosurgery, following the guidelines developed by American College of Chest Physicians (ACCP) and used by the most important medical societies such as American Association of Neurological Surgeons (AANS) and European Association of Neurosurgical Societies (EANS). Several studies have demonstrated that IPC use is effective as LMWH, safe and economic
PdFVIII/VWF may be an alternative treatment for old medical patient with acquired haemophilia A and systemic vascular disease?
Acquired Haemophilia is a severe, rare and potentially life-threatening bleeding that affects both males and females with an incidence of 1.5. cases/million/year. Mucocutaneous haemorrhages or haematomas are the typical expression of this disease as a consequence of a decrease in FVIII activity and the presence of a FVIII inhibitor, which differs from congenital haemophilia. We report a case of a 71. year-old-man who presented with spontaneous haematomas and severe anaemia and suffered from vascular disease. At admission, all haemostatic and laboratory data were diagnostic for idiopathic AHA. Treatment with by-passing agents such as rFVIIa was contraindicated because of the risk of thromboembolic events. Despite the fact that administration of FVIII concentrates in AHA is recommended only in patients with an inhibitor titre. <. 5.0. BU, the physicians decided to use pdFVIII/vWF with corticosteroids in this patient. One month later, the FVIII was within the normal range and the inhibitors had disappeared. In our case, pdFVIII/vWF resulted in a safe and effective alternative for the treatment of acquired haemophilia A in a patient at high thromboembolic risk. © 2012 Elsevier Ltd
Intracranial haemorrhage in children and adults with haemophilia A and B: A literature review of the last 20 years
Intracranial haemorrhage (ICH) is the most serious event in haemophiliacs, resulting in high rates of mortality and disability. Although the use of a prophylaxis regimen has improved outcomes, the mortality caused by ICH is still around 20%. ICH is more frequent at two different ages: in childhood (mostly in children aged ≤2 years) and in adulthood (with known risk factors such as hypertension and age ≥60 years). Our review shows how ICH remains one of the worst problems of patients with haemophilia. Greater attention to risk factors and early symptoms, together with an appropriate early prophylaxis, may reduce the risk of severe intracranial haemorrhagic events
Savings without changing: How to use the MyPKfit® device to improve treatment strategies in a cohort of patients with haemophilia A
Background: The real goal on haemophilia treatment is to combine efficacy, safety, improvement in quality of life and cost-savings. Sometimes the choice for reaching this result is to switch the patients to an extended half-life (EHL) drug. In case of haemophilia A this goal is not always achieved due to the less pharmacokinetic (PK) differences among EHL and standard concentrates. A better and regular use of available tools, as MyPKfit®, can then optimize the treatment without distorting therapy or changing concentrate. Methods: We now report our experience with a population of severe or moderate haemophilia A patients treated with octocog-alfa (Advate® –Shire Takeda) and in which a tailored prophylaxis with MyPKfit® has been assessed. Results: PK evaluations of 14 patients were carried out. A Bayesian curve and a tailored prophylaxis were assessed individually employing PK data. The weekly frequency of infusions was reduced in three severe patients, it was increased in four while it remained the same in the others five patients. The annual consumption of concentrate was reduced in 81.8% of patients. A subsequent economic evaluation carried out for each of the twelve severe haemophilia A patients included in this analysis, in which we have compared the standard and the PK-driven prophylaxis, showed that an optimized treatment can lead to an annual average saving of € 20,525 (−15.8%). Conclusions: The use of MyPKfit® for a tailored prophylaxis may lead to a more rational use of available resources through an easy correction of the treatment strategies without distorting the individual patient therapy
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