1,721,320 research outputs found

    Fisiologia cutanea di base

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    La terapia fotodinamica

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    Agronomical use of sewage sludge from Urban Waste Water Treatment : heavy metals in Zea Mais

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    The Urban Waste Water Treatment Directive (91/271/EEC) aims to encourage the use of sludge whenever appropriate ; the Sewage sludge is a product of wastewater treatment which could find a reutilisation in the agricultural field. The necessity to find a solution to the sewage and biomass disposal has lead to the development of techniques based on natural reuse of agricultural soils. In this way it represents, through a closed loop system, a source of all the nutritional elements which has been remove by the agriculture. The sewage sludge application on soils represents an alternative to the traditional stock strategies ; more convenient, from the economical point of view, than incineration or disposal in landfill, it also contributes to solve the sewage sludge recycling issue. The aim of this project is to grow up maize under experimental conditions, in order to evaluate the nutrients contribution of the sewage sludge on the final production, while observing the connection between application of sewage sludge and residual heavy metals concentration in the different plant parts

    Clinical management of cutaneous toxicity of anti-EGFR agents

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    Cutaneous toxicity is the most evident adverse effect of epidermal growth factor receptor (EGFR) inhibitors because of the specific role played by EGFR in skin biophysiology. Dermatological adverse reactions, mainly folliculocentric, have been widely reported in the literature. However, the mechanism of these reactions is not well defined and their management is still a matter of debate. In this paper keratinocyte differentiation, activation and pathways regulating gene expression are reviewed in order to improve the understanding of adverse skin reactions and obtain success in their management. The authors had the opportunity to treat skin reactions induced by cetuximab in a cohort of patients affected by metastatic colorectal carcinoma. The aims of this clinical approach were to control the signs and symptoms of skin toxicity in order to avoid delay in cancer therapy and to use nondrug agents for the treatment of drug-induced skin reactions

    Photodynamic therapy-a promising treatment option for autoimmune skin ulcers: a case report

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    We describe a 38-year-old woman with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) who developed two symmetric paramalleolar ulcers with similar diameters, depths and borders, that were successfully treated with photodynamic therapy with 5-aminolevulinic acid (ALA-PDT
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