193 research outputs found
Transition from ziprasidone im to oral formulation in agitated patients with acute exacerbation of schizophrenia: an open trial
No full textIntroduction: A transition from IM to oral formulation of an antipsychotic agent is often required during the long-term management of schizophrenia. This multicenter trial evaluates the IM/oral sequential administration of ziprasidone in agitated subjects with an exacerbation of schizophrenia.
Methods: Adult patients requiring IM therapy for schizophrenic symptoms were assigned to IM ziprasidone 10 mg for 3 days, followed by oral ziprasidone (initial dose: 80 mg/day) for 8 weeks. The primary efficacy outcomes were the change in the total PANSS and in the CGI-S scores vs. baseline values.
Results: In total, 150 patients were included in the study. A decline in the PANSS and CGI-S scores was observed throughout the study (p < 0.0001 vs. baseline): these reductions became significant at the point of transition from IM to oral formulation (p < 0.0001 vs. baseline).
Discussion: Even with the limitations of any non-comparative study, these results suggest that the IM/oral sequential administration of ziprasidone is an effective and well tolerated therapeutic option in the management of acute exacerbations of schizophrenia in agitated patients
Il turismo nelle aree protette: una potenziale risorsa per lo sviluppo sostenibile. Due esperienze di studio in Campania
No full textA. Della Bella, S. Zorzetto (a cura di), Whisteblowing e prevenzione dell’illegalità, Giuffrè Francis Lefebvre, Milano, 2020
No full textA new architecture for systems supplying essential loads in the Italian High-Speed Railway (HSR)
No full text
Formulazione per la predizione delle frecce di travi e solette di calcestruzzo armato con barre di FRP
No full textPerformance of steel-concrete composite bridges in fire
No full textIn assessing the damage on bridges caused by a fire, we should not only consider the possibility of
structural collapse, which often is avoided thanks to the beneficial effect of the ventilation that cools
the hot fumes propagating during fire. Indeed checks on the maximum deflection that the structure
can undergo during fire can be more significant for the functionality after fire of electrical, gas and
water systems often included in the bridge structures connecting different urban and extra urban
areas. Therefore, fluid dynamic and thermomechanical numerical analyses were performed to
simulate the behavior of typical bridges of the national highway during a fire, to identify possible
fire risk mitigation for avoiding the collapse of the structures and the damage of the facilities
Air quality monitoring in piggeries through an IoT gas and environmental sensors device
No full textAir quality in piggeries is linked with ammonia (NH3), carbon dioxide (CO2), particulate matter (PM2.5 and PM10) and hydrogen sulfide (H2S) concentrations. These gases have negative effects on pigs health and on environment. The air quality depends on several aspects, among which frequency of slurry removal and floor type. In this study, two naturally ventilated piggeries characterized by different housing structures and slurry management systems, were monitored: fully slatted floor with vacuum system for frequent slurry removal (Barn F), solid concrete floor in the indoor and outdoor area of the pen (Barn S). The piggeries were monitored for 21 days by installing an IoT gas and environmental sensors device equipped with sensors to continuously detect NH3, CO2, H2S and PM concentration, but also temperature and humidity. The continuous monitoring of air quality can support the farmer to better control the animal welfare and health, which is in line with precision livestock farming (PLF) principles. Specifically, manure removal from the outdoor lane of Barn S enhanced the emission of H2S up to 1.9 ppm, while the valve vacuum opening in Barn F increased the NH3 concentration of 63%. Furthermore, the automated window management system of Barn F, resulted in the accumulation of gases during the night in barn (CO2 and NH3 increasing up to 52% and 34% than daily average value, respectively) showing how the Barn S with access to an outdoor lane did not exhibit a similar increase. During the feeding distribution events PM increased by in the barn with slatted floor up to 32% than daily average value
Are energy crops a real opportunity for marginal lands enhancement? Land use change scenarios building in Southern Italy
No full textAs result of a strong anthropic pressure, all European landscape is increasingly becoming a complex entity, implying the need for specific management and planning approaches based on a specific knowledge. “Marginal lands” usually present socio-economic and geographic disadvantages, but often are also important environmental and natural reserves. Energy crops cultivation in marginal lands can be considered a useful opportunity for farmers, against the progressive risk of under-utilization or abandonment. The aim of this work is to support land-use and landscape planning to guarantee development opportunities, preserving and enhancing the natural heritage. Inside the study area (an interregional context between Molise and Campania regions - Southern Italy) marginal lands were identified starting from regulatory tools and a spatial multicriteria analysis. Three different scenarios were built: 1) No changes in land use; 2) energy crops cultivation in “fringe areas”, 3) land-use abandonment. The results show about 15% of the study area is identifiable as “Fringe areas”, identified by means of S-MCDA. Results validate the LUC scenarios built by means of S-MCDA approach and highlight the close connection and the utility of integration among ecological indicators, in landscape planning and LUC scenarios building and assessment in the ex-ante evaluation stage
La disciplina generale degli Enti del Terzo Settore
No full textQuestione di costituzionalità rinvio contratti collettivi per determinazione condizioni economiche e normative dei rapporti di lavoro (art. 16 del Codice)
- …
