257,918 research outputs found
Recharge areas and geochemical evolution of groundwater in an alluvial aquifer system in the Sultanate of Oman
No full textA regional hydrogeochemical model was developed to evaluate the geochemical evolution of different groundwaters in an alluvial aquifer system in the Interior of Oman. In combination with environmental isotopes the model is able to extract qualitative and quantitative information about recharge, groundwater flow paths and hydraulic connections between different aquifers. The main source of water to the alluvial aquifer along the flow paths of Wadi Abyadh and Wadi M’uaydin in the piedmont is groundwater from the high-altitude areas of the Jabal Akhdar and local infiltration along the wadi channels. In contrast, the piedmont alluvial aquifer along Wadi Halfayn is primarily replenished by lateral recharge from the ophiolite foothills to the east besides smaller contributions from the Jabal Akhdar and local infiltration. Further down gradient in the Southern Alluvial Plain aquifer a significant source of recharge is direct infiltration of rain and surface runoff, originating from a moisture source that approaches Oman from the south. The model shows that the main geochemical evolution of the alluvial groundwaters occurs along the flow path from the piedmont to the Southern Alluvial Plain, where dedolomitization is responsible for the observed changes in the chemical and carbon isotope composition in these waters
Small asymmetric Brownian objects self-align in nanofluidic channels
No full textAlthough the self-alignment of asymmetric macro-sized objects of a few tens of microns in size have been studied extensively in experiments and theory, access to much smaller length scales is still hindered by technical challenges. We combine molecular dynamics and stochastic rotation dynamics techniques to investigate the self-orientation phenomenon at different length scales, ranging from the micron to the nano scale by progressively increasing the relative strength of diffusion over convection. To this end, we model an asymmetric dumbbell particle in Hele-Shaw flow and explore a wide range of Péclet numbers (Pe) and different particle shapes, as characterized by the size ratio of the two dumbbell spheres (R). By independently varying these two parameters we analyse the process of self-orientation and characterize the alignment of the dumbbell with the direction of the fluid flow. We identify three different regimes of strong, weak and no alignment and we map out a state diagram in Pe versus R plane. Based on these results, we estimate dimensional length scales and flow rates for which these findings would be applicable in experiments. Finally, we find that the characteristic reorientation time of the dumbbell is a monotonically decreasing function of the dumbbell anisotropy.Accepted Author ManuscriptComplex Fluid Processin
Vanishing White Matter Disease Associated With Ptosis and Myoclonic Seizures
No full textA 5-year-old boy who presented with progressive ataxia, neuroregression, and worsening with febrile illnesses is described. He also had myoclonic jerks and ptosis. His elder sister had died of a similar illness. Serial magnetic resonance imaging of the brain demonstrated extensive abnormality of the cerebral white matter with rarefaction and cystic degeneration, suggestive of vanishing white matter disease. The patient was found to be compound heterozygous for 2 new mutations in the gene EIF2B5, confirming the diagnosis. © The Author(s) 2011
Edward S. Curtis
No full textThese indelible portraits of Native Americans by Edward S. Curtis, made at the dawn of the 20th Century, have become among the most avidly collected, published, and sought-after emblems of early encounters with American Indian life. Curtis is famous for photographing every major Native American tribe west of the Mississippi, taking more than 40,000 negatives of 80 tribes between 1896 and 1930. No record of these Native people from this period is more comprehensive. Now, after decades in obscurity, Curtis\u27s work is enjoying a renaissance and is being celebrated in a series of exhibitions as well as in publication that have just begun to suggest the scope of this remarkable photographic achievement. This book, the first in a series that will take an in-depth look at many of the subjects most important to Curtis, collects 100 of his most compelling images of tribal leaders and warriors. They are drawn from the collection of Christopher Cardozo and feature iconic Curtis pictures as well as several little-known gems
Semiclassical magnetotransport in strongly spin-orbit coupled Rashba two-dimensional electron systems
No full textSemiclassical magnetoelectric and magnetothermoelectric transport in strongly spin-orbit coupled Rashba two-dimensional electron systems is investigated. In the presence of a perpendicular classically weak magnetic field and short-range impurity scattering, we solve the linearized Boltzmann equation self-consistently. Using the solution, it is found that when Fermi energy EF locates below the band crossing point (BCP), the Hall coefficient is a nonmonotonic function of electron density ne and not inversely proportional to ne. While the magnetoresistance (MR) and Nernst coefficient vanish when EF locates above the BCP, non-zero MR and enhanced Nernst coefficient emerge when EF decreases below the BCP. Both of them are nonmonotonic functions of EF below the BCP. The different semiclassical magnetotransport behaviors between the two sides of the BCP can be helpful to experimental identifications of the band valley regime and topological change of Fermi surface in considered systems.National Natural Science Foundation of China [11274018]SCI(E)[email protected]
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis.
No full textObjectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death.
Design: Systematic review and meta-analysis.
Data sources: PubMed from 1966 to 23 November 2009.
Study selection: Prospective longitudinal studies that used magnetic resonance imaging and assessed the impact of white matter hyperintensities on risk of incident stroke, cognitive decline, dementia, and death, and, for the meta-analysis, studies that provided risk estimates for a categorical measure of white matter hyperintensities, assessing the impact of these lesions on risk of stroke, dementia, and death.
Data extraction: Population studied, duration of follow-up, method used to measure white matter hyperintensities, definition of the outcome, and measure of the association of white matter hyperintensities with the outcome.
Data synthesis: 46 longitudinal studies evaluated the association of white matter hyperintensities with risk of stroke (n=12), cognitive decline (n=19), dementia (n=17), and death (n=10). 22 studies could be included in a meta-analysis (nine of stroke, nine of dementia, eight of death). White matter hyperintensities were associated with an increased risk of stroke (hazard ratio 3.3, 95% confidence interval 2.6 to 4.4), dementia (1.9, 1.3 to 2.8), and death (2.0, 1.6 to 2.7). An association of white matter hyperintensities with a faster decline in global cognitive performance, executive function, and processing speed was also suggested.
Conclusion: White matter hyperintensities predict an increased risk of stroke, dementia, and death. Therefore white matter hyperintensities indicate an increased risk of cerebrovascular events when identified as part of diagnostic investigations, and support their use as an intermediate marker in a research setting. Their discovery should prompt detailed screening for risk factors of stroke and dementia
- …
