314 research outputs found
sj-docx-1-jic-10.1177_08850666231186947 - Supplemental material for Discordance Between Invasive and NonInvasive Oxygen Saturation in Critically Ill COVID-19 Patients
No full textSupplemental material, sj-docx-1-jic-10.1177_08850666231186947 for Discordance Between Invasive and NonInvasive Oxygen Saturation
in Critically Ill COVID-19 Patients by Thomas H. Fox, MD, William R. Mazalewski, DO, Hai S. Tran, MD, Travis Lindsey, MD, Amita Krishnan, MD, Stephen P. Kantrow, MD, Kyle I. Happel, MD, FCCP, David R. Janz, MD, Bennett P. deBoisblanc, MD, FACP, FCCP, FCCM, and Matthew R. Lammi, MD, MSCR in Journal of Intensive Care Medicine</p
sj-docx-1-ine-10.1177_15910199221138139 - Supplemental material for Multicenter investigation of technical and clinical outcomes after thrombectomy for Proximal Medium Vessel Occlusion (pMeVO) by frontline technique
No full textSupplemental material, sj-docx-1-ine-10.1177_15910199221138139 for Multicenter investigation of technical and clinical outcomes after thrombectomy for Proximal Medium Vessel Occlusion (pMeVO)
by frontline technique by Jonathan A Grossberg, Reda M Chalhoub, Sami Al Kasab, Dominika Pullmann, Pascal Jabbour, Marios Psychogios, Robert M Starke, Adam S Arthur, Kyle M Fargen, Reade De Leacy, Peter Kan, Travis Dumont, Ansaar Rai, Roberto J Crosa, Kareem E Naamani, Ilko Maier, Nitin Goyal, Stacey Quintero Wolfe, C Michael Cawley, J Mocco, Muhammad Hafeez, Brian M Howard, Laurie Dimisko, Hassan Saad, Christopher S Ogilvy, R Webster Crowley, Justin Mascitelli, Isabel Fragata, Michael Levitt, Alejandro M Spiotta and Ali M Alawieh in Interventional Neuroradiology</p
Easterner, Vol. 63, No. 18, February 29, 2012
No full textThis issue of the Easterner contains articles about track athlete Kyle King, a Republican campaign event featuring Newt Gingrich, the mock trial team, Cheney entrepreneurs, Law Day events, an engineering egg drop activity, the Smile for Veterans Day event, an event featuring actors Carlos Alazraqui and Cedric Yarbrough, a modernized student production of Antony and Cleopatra, author and administrative assistant Travis Naught, alumna and Olympian Julie Page, men\u27s hockey, figure skater Anna Stokes, and the sportsman\u27s club.https://dc.ewu.edu/student_newspapers/1739/thumbnail.jp
Outcomes of Rescue Endovascular Treatment of Emergent Large Vessel Occlusion in Patients With Underlying Intracranial Atherosclerosis: Insights From STAR
No full textBackground Some emergent large vessel occlusions (ELVOs) are refractory to reperfusion because of underlying intracranial atherosclerosis (ICAS), often requiring rescue therapy (RT) with balloon angioplasty, stenting, or both. In this study, we investigate the safety, efficacy, and long‐term outcomes of RT in the setting of mechanical thrombectomy for ICAS‐related ELVO. Methods and Results We queried the databases of 10 thrombectomy‐capable centers in North America and Europe included in STAR (Stroke Thrombectomy and Aneurysm Registry). Patients with ELVO who underwent ICAS‐related RT were included. A matched sample was produced for variables of age, admission National Institute of Health Stroke Scale, Alberta Stroke Program Early CT Score, onset to groin puncture time, occlusion site, and final recanalization. Out of 3025 patients with MT, 182 (6%) patients required RT because of underlying ICAS. Balloon angioplasty was performed on 122 patients, and 117 patients had intracranial stenting. In the matched analysis, 141 patients who received RT matched to a similar number of controls. The number of thrombectomy passes was higher (3 versus 1, P <0.001), and procedural time was longer in the RT group (52 minutes versus 36 minutes, P =0.004). There was a higher rate of symptomatic hemorrhagic transformation in the RT group (7.8% versus 4.3%, P =0.211), however, the difference was not significant. There was no difference in 90‐day modified Rankin scale of 0 to 2 (44% versus 47.5%, P =0.543) between patients in the RT and control groups. Conclusions In patients with ELVO with underlying ICAS requiring RT, despite longer procedure time and a more thrombectomy passes, the 90 days favorable outcomes were comparable with patients with embolic ELVO.Background Some emergent large vessel occlusions (ELVOs) are refractory to reperfusion because of underlying intracranial atherosclerosis (ICAS), often requiring rescue therapy (RT) with balloon angioplasty, stenting, or both. In this study, we investigate the safety, efficacy, and long‐term outcomes of RT in the setting of mechanical thrombectomy for ICAS‐related ELVO. Methods and Results We queried the databases of 10 thrombectomy‐capable centers in North America and Europe included in STAR (Stroke Thrombectomy and Aneurysm Registry). Patients with ELVO who underwent ICAS‐related RT were included. A matched sample was produced for variables of age, admission National Institute of Health Stroke Scale, Alberta Stroke Program Early CT Score, onset to groin puncture time, occlusion site, and final recanalization. Out of 3025 patients with MT, 182 (6%) patients required RT because of underlying ICAS. Balloon angioplasty was performed on 122 patients, and 117 patients had intracranial stenting. In the matched analysis, 141 patients who received RT matched to a similar number of controls. The number of thrombectomy passes was higher (3 versus 1, P <0.001), and procedural time was longer in the RT group (52 minutes versus 36 minutes, P =0.004). There was a higher rate of symptomatic hemorrhagic transformation in the RT group (7.8% versus 4.3%, P =0.211), however, the difference was not significant. There was no difference in 90‐day modified Rankin scale of 0 to 2 (44% versus 47.5%, P =0.543) between patients in the RT and control groups. Conclusions In patients with ELVO with underlying ICAS requiring RT, despite longer procedure time and a more thrombectomy passes, the 90 days favorable outcomes were comparable with patients with embolic ELVO
Binding and control: a unified approach
No full textThis thesis presents a theory that explains binding and control with common mechanisms. Although a unified account of the two phenomena was frequently attempted in the 1980's and early 90's, such an approach seems to have been unpopular due to certain problems since the late 90's. In this study it is shown that these problems are merely superficial and can be overcome with careful examination. In chapter 2, I start with Reinhart & Reuland's (1993) assumption that the application of Condition A of binding theory is restricted to anaphors in argument positions of syntactic predicates. I then adopt Fox's (1993) modification to Reinhart & Reuland's (1993) theory, whereby Condition A is reduced to the Chain Condition. As the discussion proceeds, further revisions are suggested. In particular, the domain for A-chain formation is defined over syntactic predicates, which is called the A-Chain Projection Domain (ACPD). With respect to anaphors that are not in argument positions of syntactic predicates, I entertain the hypothesis by the above authors that they are what are often called logophors, which are governed by a set of discourse conditions. I identify some of these conditions and explore some possibilities as to how such discourse conditions can be organized into a formalized theory. In chapter 3, it is maintained that PRO in obligatory control (OC) contexts is licensed by the Chain Condition. Discussed also are some of the objections raised by a number of researchers to the idea that the same mechanism underlies OC PRO and anaphors (in argument positions of syntactic predicates). Furthermore, it is illustrated that PRO in non-obligatory control (NOC) environments is logophoric and is licensed by discourse conditions. Lastly, it is argued that there exist control constructions that look very much like OC but are, in fact, properly classified as NOC, which I term pseudo-obligatory control (POC). In chapCette these presente une theorie qui explique le liage et le controle a l'aide de mecanismes communs. Bien qu'une explication unifiee des deux phenomenes ait ete frequemment tentee dans les annees 80 et 90, une telle approche semble avoir ete impopulaire a cause de certains problemes depuis la fin des annees 90. Dans cette etude il est demontre que ces problemes ne sont que superficiels et qu'ils peuvent etre surmontes par un examen attentif. Dans le Chapitre 2, je commence avec la presomption de Reinhart & Reuland (1993) selon laquelle l'application de la Condition A de la theorie du liage est restreinte aux anaphores en position d'argument de predicats syntaxiques. J'adopte ensuite la modification que Fox (1993) a apportee a la theorie de Reinhart & Reuland (1993), selon laquelle la Condition A est reduite a la Condition de Chaine. Au cours de la discussion, d'autres revisions sont suggerees. En particulier, le domaine de la formation de la chaine A est definie en termes de predicats syntaxiques, que j'appelle le Domaine de Projection de la Chaine A (DPCA). En ce qui concerne les anaphores qui ne sont pas en positions de predicats syntaxiques, je considere l'hypothese des auteurs cites plus haut selon laquelle elles sont souvent appelees des logophores, lesquelles sont gouvernees par un ensemble de conditions discursives. J'identifie certaines de ces conditions et explore certaines possibilites selon lesquelles de telles conditions discursives peuvent etre organisees en une theorie formalisee. Au chapitre 3, je maintiens que PRO en contexte de controle obligatoire (CO) est licencie par la Condition de Chaine. J'examine egalement certaines des objections a l'idee que le meme mecanisme sous-tende PRO OC et les anaphores (en positions d'arguments de predicats syntaxiques) soulevees par un nombre de chercheurs. De plus, je montre que PRO en environnements de controle non obligatoire (CNO) est logoph
Venn Diagram Applet
No full textIn this applet, A and B are subsets of a universal set S. The list is given of the 16 different subsets of S that can be constructed from A and B using the basic set operations of union, intersection, and complement. The selected subset is colored red in the Venn diagram on the right
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Wind energy harvesting for bridge health monitoring
No full texttextThe work discussed in this thesis provides a review of pertinent literature, a design methodology, analytical model, concept generation and development, and conclusions about energy harvesting to provide long-term power for bridge health monitoring. The methodology gives structure for acquiring information and parameters to create effective energy harvesters. The methodology is used to create a wind energy harvester to provide long-term power to a wireless communication network. An analytical model is developed so the system can be scaled for different aspects of the network. A proof of concept is constructed to test the methodology's effectiveness, and validate the feasibility and analytical model.Mechanical Engineerin
Adapting Commercial Best Practices to U.S. Air Force Maintenance Scheduling
No full textThis paper presents how the Inspection Development Framework’s (IDF) novel maintenance scheduling technique increased aircraft utilization and availability in a sample of the United States Air Force’s (USAF) C-5M Super Galaxy fleet. The hypothesis tested was “Can we execute segmented maintenance requirements during ground time opportunities in order to optimize flying?” We applied IDF to decompose the C-5M’s five-day Home Station Check (HSC) inspection into smaller work packages that subordinate to operational requirements and maintenance resource availability. Ten HSCs at Dover and Travis Air Force Base (AFB) were modified using IDF and measured against a control group of traditional HSCs. While statistical significance was not achieved given the small sample size, anecdotal results demonstrate improvements in maintenance downtime, sortie count, and flight hours for the experimental group across the two bases. Specifically, the pathfinder’s observed results extrapolated to all HSCs at each base projected an additional 15 flying days per year at Dover AFB and 29 sorties per year at Travis AFB. These C-5M improvements serve as a proof-of-concept for the USAF adapting commercial best practices to address declining aircraft readiness. IDF’s more agile and dynamic scheduling techniques also enable easier adoption of Condition Based Maintenance through a more integrated approach to optimally schedule maintenance requirements
Repeated application of a novel creatine cream improves muscular peak and average power in male subjects
No full textUsing a multicenter, randomized controlled trial, (N = 123, age 23 [+ or -] 4 years) we sought to determine whether administration of a novel, topical creatine supplement could improve muscular performance after acute and repeated (7-day) exposure. To study the acute performance enhancing effects of the supplement, subjects completed 5 sets of 15 maximal concentric single-leg knee extensions with and without the application of a low- (low dose [LD]-3.5 ml) or high-dose (high dose [HD]-7 ml) topical creatine cream. After a wash-out period, subjects had one leg randomized to receive either the creatine or placebo cream, with further randomization into an oral creatine or placebo supplement group. Subjects completed 5 sets of 15 maximal concentric single leg knee extensions before and after the supplementation protocol. After acute application, no significant differences in peak power (LD: 252 [+ or -] 93 W, HD: 261 [+ or -] 100 W, p = 0.21), average power (LD: 172 [+ or -] 65 W, HD: 177 [+ or -] 69 W, p = 0.78), or fatigue index (LD: 13.4 [+ or -] 10.6%, HD: 14 [+ or -] 11.9%, p = 0.79) were observed between experimental and placebo creams (peak power: LD: 244 [+ or -] 76 W, HD: 267 [+ or -] 109 W; average power: LD: 168 [+ or -] 57 W, HD: 177 [+ or -] 67 W; fatigue index: LD: 12.4 [+ or -] 9.6%, HD: 12.8 [+ or -] 10.6%) or when controlling for sex. After the 7-day supplementation protocol, a significant increase in average power (creatine: 203 [+ or -] 61-220 [+ or -] 65 W, placebo: 224 [+ or -] 61-214 [+ or -] 61 W) and peak power (creatine: 264 [+ or -] 73-281 [+ or -] 80 W, placebo: 286 [+ or -] 79-271 [+ or -] 73 W) in the leg receiving creatine cream was observed in male subjects. No differences were observed in female subjects. The topical creatine cream did not enhance measures of muscle performance after acute application, but was able to improve peak and average power in male subjects after 7 consecutive days of application
Field-ready biomarkers for quantifying dehydration: applications for mountain and high-altitude warfighters
No full textBackground Dehydration is a critical threat to performance and safety in tactical settings, particularly during prolonged activity in heat or altitude while wearing heavy gear. Sweat-prone regions like the chest, back, and lower legs, which are areas typically covered by packs, armor, and boots, may experience accelerated fluid loss. This study evaluated whether noninvasive salivary biomarkers and regional skin temperatures could serve as practical indicators of hydration status.Methods Ten males (25.5 ± 3.5 yrs, 179.9 ± 7.2 cm, 78.1 ± 8.5 kg) completed a 2-hour treadmill run without fluid intake. Saliva and skin temperature measurements were collected every 15 minutes (8 timepoints). Biomarkers (osmolality, chloride, and cortisol) and regional skin temperatures (chest, back, lower leg) were analyzed relative to dehydration. Total body water (TBW) loss and percent dehydration were used as outcomes. Bayesian Pearson correlations (r) and Bayes Factors (BF10) assessed associations, with magnitude and evidence strength classified using Hopkins and Jeffreys scales. Bayesian multiple regression models (R2) evaluated predictive contributions of each variable, with model outputs including Bayes factor inclusion scores (BFincl) and standardized beta coefficients (ß). Analyses were performed in JASP (v0.19.3).Results Salivary osmolality (BF10 = 58.00; r = –0.142) and chloride (BF10 = 53.25; r = –0.010) were supported by very strong evidence as predictors of total body water (TBW) loss, though both exhibited small, inverse associations with TBW loss. Cortisol (BF10 = 23.55; r = 0.311) exhibited strong evidence and a moderate positive correlation, increasing as TBW loss increased. Chest temperature demonstrated the strongest predictive contribution in the regression model (BFincl = 1874.60; ß = –0.167), followed by lower leg (BFincl = 45.82; ß = –0.153) and back (BFincl = 34.81; ß = –0.145). Negative beta coefficients reflected positive associations between rising surface temperatures and greater dehydration. Fluid-based models explained up to 70.6% of TBW loss variance (R2 = 0.706), outperforming temperature-only models (R2 = 0.451). When models were replicated using percent dehydration as the outcome, results remained consistent; chest temperature remained the most consistently included thermal predictor (BF10 = 7.34), though the strength of its association was small.Conclusions Salivary osmolality, chloride, and cortisol, along with chest, back, and lower leg temperature, show strong promise as noninvasive, field-ready indicators of dehydration. These findings support the use of portable thermal sensors and saliva-based tools to help tactical personnel monitor hydration status during sustained operations in austere environments
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